茶成分对肠道菌群的调控作用及其健康效应的研究进展  

Research progress on the regulatory mechanism of tea components on gut microbiota and its health benifits

作　　者：储思远 钱利生 陈海敏[1,2] CHU Si-yuan;QIAN Li-sheng;CHEN Hai-min(Zhejiang Province Key Laboratory of Plant Secondary Metabolism and Regulation,College of Life Sciences and Medicine,Zhejiang Sci-Tech University,Hangzhou 310018,China;Shaoxing Academy of Biomedicine,Zhejiang Sci-Tech University,Shaoxing 312369,China;College of Agriculture and Biotechnology,Zhejiang University,Hangzhou 310058,China)

机构地区：[1]浙江理工大学生命科学与医药学院浙江省植物次生代谢调控重点实验室,杭州310018 [2]浙江理工大学绍兴生物医药研究院,绍兴312369 [3]浙江大学农业与生物技术学院,杭州310058

出　　处：《天然产物研究与开发》2024年第2期357-367,共11页Natural Product Research and Development

基　　金：浙江省自然科学基金(LY22H280011);浙江理工大学绍兴生物医药研究院开放基金(SXAB202203);浙江理工大学科研启动基金(21042252-Y)。

摘　　要：茶是世界上最受欢迎的健康饮料之一,富含茶多酚、茶多糖、茶色素和茶皂素等多种生物活性成分,对人体健康具有重要影响。肠道是一个复杂而稳定的生态系统,肠道微生态与人体健康密切相关。肠道菌群是茶成分发挥生理调节作用和健康效应的主要作用靶点,本文对近年来几种重要茶成分对肠道菌群的调节作用及其对机体健康的影响相关研究进展进行了综述。茶成分主要通过靶向肠道菌群调节糖代谢和脂代谢,减轻炎症和肠道损伤,缓解情绪和记忆障碍以及调节昼夜节律,发挥其健康效应。阐明茶成分调控肠道菌群的内在作用机制将为更好地利用茶产品来改善肠道微生态,促进人体健康提供科学依据。Tea is one of the most popular health drinks in the world,with a variety of effective bioactive ingredients,including tea polyphenols,tea polysaccharides,tea pigments,tea saponins and other bioactive components,which contributes to human health.Intestinal tract is a complex and stable ecosystem,while intestinal microecology is closely associated to human health.Gut microbiota performs an important target for tea components to exert physiological regulation and health effects.Here,the progress on intervention and regulation mechanism of these tea components on gut microbiota and their effects on body health in recent years were reviewed.Tea ingredients exert their health benefits mainly by targeting on gut microbiota to regulate glucose metabolism and lipid metabolism,or relieve inflammation and intestinal damage,or alleviate mood and memory disorders,and regulate circadian rhythms.To clarify the internal mechanism of tea components regulating gut microbiota will provide a scientific basis for better utilization of tea products to improve intestinal microecology and promote human health.

关 键 词：茶多酚 茶色素 茶多糖 茶籽皂素 肠道菌群 健康效应 

分 类 号：TS201.4[轻工技术与工程—食品科学]