纳米生物传感器在食源性致病菌检测中的应用研究进展  

Recent Progress on the Application of Nano-Biosensors for the Detection of Foodborne Pathogenic Bacteria

作　　者：张红梅 高雪 刘璐 贾穆 励建荣 ZHANG Hongmei;GAO Xue;LIU Lu;JIA Mu;LI Jianrong(Liaoning Provincial Key Laboratory of Food Safety,National Joint Engineering Research Center for Storage,Processing and Safety Control Technology of Fresh Agricultural Products,College of Food Science and Engineering,Bohai University,Jinzhou 121013,China)

机构地区：[1]渤海大学食品科学与工程学院,辽宁省食品安全重点实验室,生鲜农产品贮藏加工及安全控制技术国家地方联合工程研究中心,辽宁锦州121013

出　　处：《食品科学》2024年第3期348-357,共10页Food Science

摘　　要：食源性致病菌污染对人们的健康造成了极大的威胁,传统检测方法操作繁琐且不能实时检测,因此,构建一种灵敏、安全、简便且消耗少的食源性致病菌检测方法很有探索意义。与传统方法相比,基于纳米生物传感器的检测技术具有特异灵敏、简易快速、检测实时、材料消耗少和检测限低等优势,本文主要阐述了基于纳米生物传感器的方法,并展开讨论了其中单模式、双模式及多模式检测的原理及应用优势,同时对纳米生物传感器在食源性致病菌检测中的应用前景提出展望,以期为优化食源性致病菌的检测方法提供一定参考。The contamination of foodborne pathogenic bacteria poses great threats to human health.Conventional foodborne pathogen detection methods suffer from the shortcomings of time-consuming,cumbersome,and non-real time.Hence,it is of great significance to explore a sensitive,safe,simple and economical method for foodborne pathogen detection.Compared with the traditional methods,nano-biosensor-based detection assays possess merits such as exceptional sensitivity,high selectivity,real-time detection,low consumption and low limit of detection.In this article,these nano-biosensor-based methods are summarized,and the principles and advantages of single-,dual-and multi-mode detection are comprehensively discussed.Meanwhile,an outlook on the application of nano-biosensors for the detection of foodborne pathogens is given with the goal of providing a reference for the optimization of the existing detection methods for foodborne pathogenic bacteria.

关 键 词：食源性致病菌 纳米生物传感器 单模式 双模式 多模式 

分 类 号：TS207.4[轻工技术与工程—食品科学]