彩麦麸皮戊聚糖泡腾片的制备及其降血糖活性评价  

Preparation and hypoglycemic activity of effervescent tablets containing pentosan from color wheat bran

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作  者:位思清 王岩 薛永杰 高鹏 唐晓珍[2] WEI Si-qing;WANG Yan;XUE Yong-jie;GAO Peng;TANG Xiao-zhen(Shandong Foreign Trade Vocational College,Taian 271000,Shandong,China;College of Food Science and Engineering,Shandong Agricultural University,Taian 271018,Shandong,China)

机构地区:[1]山东外贸职业学院,山东泰安271000 [2]山东农业大学食品科学与工程学院,山东泰安271018

出  处:《粮食与油脂》2024年第7期98-102,共5页Cereals & Oils

基  金:泰安市科技创新发展项目(2022NS139);2020年度山东省科技特派员行动计划(2020KJTPY079)。

摘  要:研究彩麦麸皮戊聚糖降糖效果、泡腾片制备配方及其降低人体餐后血糖的效果。结果表明:当彩麦麸皮戊聚糖质量浓度为10 mg/mL时,对α-葡萄糖苷酶的抑制率为54.57%,对α-淀粉酶的抑制率为56.57%,IC_(50)分别为9.16、8.05 mg/mL;以泡腾片质量为基准,当彩麦麸皮戊聚糖添加量为20%、泡腾片崩解剂添加量为55%、碱酸质量比为1∶1.1时,泡腾片综合评分最高,为0.88;制备的泡腾片平均片重约为501 mg,每片戊聚糖含量约为56 mg,服用后餐后血糖高峰值降低率人均高达50.4%,最高达到69.6%,降低餐后血糖效果明显。The preparation and hypoglycemic activity of effervescent tablets containing pentosan from color wheat bran were investigated.The results showed that the inhibition rates ofα-glucosidase andα-amylase were 56.57%and 54.57%(the corresponding IC_(50) of 9.16 and 8.05 mg/mL),respectively,when the concentration of pentosan was 10 mg/mL.The formula with the highest comprehensive quality score of 0.88 for effervescent tablets was 20%for pentosan from color wheat bran,55%for disintegrating agent,and the alkali-acid ratio of 1∶1.1(mass ratio).The average weight and pentosan content of prepared effervescent tablets were 501 mg and 56 mg,respectively.The per capita reduction rate of postprandial high peak blood sugar was 50.4%with maximum value of 69.6%after direct consumption.Therefore,prepared effervescent tablets containing pentosan from color wheat bran significantly reduced postprandial blood sugar concentrations.

关 键 词:彩麦麸皮 戊聚糖 泡腾片 降血糖活性 

分 类 号:TS201.1[轻工技术与工程—食品科学]

 

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