Paracrine function amplifies pro-tumor electrochemical signal within neuron-glioma synapses  

作　　者：Yan Hu Peishan Hu Xiaozhong Peng 

机构地区：[1]Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE,State Key Laboratory of Biotherapy,West China Second University Hospital,Sichuan University,Chengdu 610041,China [2]Guangdong Institute of Gastroenterology,Department of General Surgery,Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases,The Sixth Affiliated Hospital,Sun Yat-sen University,Guangzhou 510655,China [3]Department of Molecular Biology and Biochemistry,Institute of Basic Medical Sciences,Medical Primate Research Center,Neuroscience Center,Chinese Academy of Medical Sciences,School of Basic Medicine Peking Union Medical College,Beijing 100730,China [4]State Key Laboratory of Respiratory Health and Multimorbidity,Institute of Basic Medical Sciences Chinese Academy of Medical Sciences,School of Basic Medicine Peking Union Medical College,Beijing 100730,China [5]Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China

出　　处：《Science China(Life Sciences)》2024年第6期1318-1320,共3页中国科学（生命科学英文版）

基　　金：supported by the National Natural Science Foundation of China(82003102)。

摘　　要：Neuronal activity plays a pivotal role in various physiological processes,including tissue development,homeostasis,and adaptability.Advances in recent years have improved our understanding of neuronal activity in brain cancers,such as glioblastoma(GBM)and diffuse midline gliomas(DMG),which are among the most prevalent and lethal cancers affecting children and adults.Generally,the neurons regulate brain cancers via two routes.

关 键 词：GLIOMA HOMEOSTASIS FUNCTION 

分 类 号：R739.4[医药卫生—肿瘤]