Isolated Autoimmune Orchitis Due to IgG4 Hypersecretion Presenting as Tumor-Like Mass: Case Report and Review of Literature  

作　　者：Francisco Marcos da Silva Barroso Flavio Antunes de Sousa Paloma Menezes de Souza Gustavo Lopes de Castro Katia Ramos Moreira Leite Monique Freire Santana Roger Arthur da Cunha Alves Gabriela Ayumi Owada Borges Juan Eduardo Rios Rodriguez Francisco Marcos da Silva Barroso;Flavio Antunes de Sousa;Paloma Menezes de Souza;Gustavo Lopes de Castro;Katia Ramos Moreira Leite;Monique Freire Santana;Roger Arthur da Cunha Alves;Gabriela Ayumi Owada Borges;Juan Eduardo Rios Rodriguez(Urology Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil;General Surgery Service, Santa Casa de Ribeirão Preto, Ribeirão Preto, Brazil;São Paulo University (USP), Ribeirão Preto, Brazil;Faculty of Medicine, Federal University of Amazonas (UFAM), Manaus, Amazonas, Brazil;Pathology Department, Sírio-Libanes Hospital, São Paulo, Brazil;Faculty of Medicine, São Paulo University (USP), São Paulo, Brazil;Patholgy Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil;Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus, Amazonas, Brazil;Teaching and Research Department, Oncology Center Control Foundation (FCECON), Manaus, Amazonas, Brazil;Urology Service, Hospital Pronto-Socorro 28 de Agosto, Manaus, Amazonas, Brazil;General Surgery Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil)

机构地区：[1]Urology Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil [2]General Surgery Service, Santa Casa de Ribeirã o Preto, Ribeirã o Preto, Brazil [3]Sã o Paulo University (USP), Ribeirã o Preto, Brazil [4]Faculty of Medicine, Federal University of Amazonas (UFAM), Manaus, Amazonas, Brazil [5]Pathology Department, Sírio-Libanes Hospital, Sã o Paulo, Brazil [6]Faculty of Medicine, Sã o Paulo University (USP), Sã o Paulo, Brazil [7]Patholgy Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil [8]Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus, Amazonas, Brazil [9]Teaching and Research Department, Oncology Center Control Foundation (FCECON), Manaus, Amazonas, Brazil [10]Urology Service, Hospital Pronto-Socorro 28 de Agosto, Manaus, Amazonas, Brazil [11]General Surgery Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil

出　　处：《Open Journal of Urology》2022年第1期51-56,共6页泌尿学期刊（英文）

摘　　要：<strong>Background:</strong> IgG4-related disease is a rare autoimmune condition that presents with lymphoplasmacytic infiltrate and fibrosis in the organ affected. Isolated testicle involvement is uncommon and there are only a few cases reported in the literature. <strong>Case</strong> <strong>Presentation:</strong> We report a case of isolated chronic orchitis due to IgG4 hypersecretion in a 61-year-old patient that evolved with asymptomatic tumor-like mass growth and was treated with left orchiectomy. Histopathological study revealed orchitis related to IgG4 hypersecretion disease. <strong>Conclusion:</strong> IgG4-related disease can be manifested as a multi or single-organ disorder. Most diagnoses are made after surgery with histopathological analysis. Most of the cases in literature stand out the difficulty in diagnosis and necessity of high suspicion due to this condition’s similarity with neoplasm presentation.<strong>Background:</strong> IgG4-related disease is a rare autoimmune condition that presents with lymphoplasmacytic infiltrate and fibrosis in the organ affected. Isolated testicle involvement is uncommon and there are only a few cases reported in the literature. <strong>Case</strong> <strong>Presentation:</strong> We report a case of isolated chronic orchitis due to IgG4 hypersecretion in a 61-year-old patient that evolved with asymptomatic tumor-like mass growth and was treated with left orchiectomy. Histopathological study revealed orchitis related to IgG4 hypersecretion disease. <strong>Conclusion:</strong> IgG4-related disease can be manifested as a multi or single-organ disorder. Most diagnoses are made after surgery with histopathological analysis. Most of the cases in literature stand out the difficulty in diagnosis and necessity of high suspicion due to this condition’s similarity with neoplasm presentation.

关 键 词：ORCHITIS IgG4-Related Disease AUTOIMMUNE TESTICLE INFLAMMATORY 

分 类 号：R57[医药卫生—消化系统]