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A multi-omics analysis of viral nucleic acid poly(I:C)responses to mammalian testicular stimulation: 《Stress Biology》2024年第1期680-691,共12页Donghui Yang Wenping Wu Qizhong Lu Yaling Mou Wenbo Chen Shicheng Wan Mengfei Zhang Congliang Wang Xiaomin Du Na Li Jinlian Hua; supported by the National Natural Science Foundation of China(32072806,20230978);the National Key Research and Development Program of China(2022YFD1302201,2023YFF1000904,2023ZD0404303);Xinjiang Ugur Autonouous Region Scientific Research and Innovation Platform Construction Project“State Key Laboratory of Genetic Improvement and Germplasm Innovation of Grass-fed Livestock Coconstruction by the Province and Ministry”,Key Technologies Demonstration of Animal Husbandry in Shaanxi Province(20221086,20230978);Inner Mongolia Autonomous Region posted leaders(2022JBGS0025).; The male reproductive system has a standard immune response regulatory mechanism,However,a variety of external stimuli,including viruses,bacteria,heat,and medications can damage the testicles and cause orchitis and ep...; 关键词：ORCHITIS Poly(I:C) Proteomic METABOLOMIC Homeostasis

Seminal plasma S100A8/A9 as a potential biomarker of genital tract inflammation被引量：1: 《Asian Journal of Andrology》2024年第5期464-471,共8页Qiu-Zi Shen Yong-Feng Wang Yi-Wei Fang Yuan-Yao Chen Li-Ting He Yuan Zhang Guo-Tao Liu Kai Zhao Chun-Yan Liu Zun-Pan Fan Hui-Ping Zhang; supported by the National Natural Foundation of China(81871148);the Open Fund of NHC Key Laboratory of Birth Defects Prevention,Henan Key Laboratory of Population Defects Prevention(Henan Institute of Reproduction Health Science and Technology,ZD202201);the Fundamental Research Funds for the Central Universities,HUST(2023JYCXJJ062 and YCJJ202201050).; Infections and inflammatory reactions in the male genital tract are the leading causes of male infertility with a prevalence of 6%-10%,primarily affecting testicular and epididymal function and ultimately compromising...; 关键词：experimental autoimmune orchitis genital inflammation male infertility PROTEOMICS S100A8/A9

Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis被引量：2: 《Asian Journal of Andrology》2023年第3期389-397,共9页Jia Xu Chao He Yi-Wei Fang Zhi-Yong Hu Mei-Lin Peng Yuan-Yao Chen Yu-Fang Su Chun-Yan Liu Hui-Ping Zhang Kai Zhao; This work was funded by National Key R&D Program of China(2018YFC1004300 and 2018YFC1004304);National Natural Foundation of China(No.81871148 and No.818701539).; Male reproductive infections are known to shape the immunological homeostasis of the testes,leading to male infertility.However,the specific pathogenesis of these changes remains poorly understood.Exosomes released in...; 关键词：male infertility miR-155-5p ORCHITIS testicular exosome testicular macrophage polarization

Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility被引量：2: 《Zoological Research》2023年第3期505-521,共17页Meng-Fei Zhang Shi-Cheng Wan Wen-Bo Chen Dong-Hui Yang Wen-Qing Liu Ba-Lun Li Aili Aierken Xiao-Min Du Yun-Xiang Li Wen-Ping Wu Xin-Chun Yang Yu-Dong Wei Na Li Sha Peng Xue-Ling Li Guang-Peng Li Jin-Lian Hua; supported by the National Natural Science Foundation of China(32072806,31572399);National Key Research and Development Program of China(2022YFD1302201);Program of Shaanxi Province Science and Technology Innovation Team(2019TD-036);Major Projects of Natural Science Foundation of Inner Mongolia Autonomous Region(2020ZD10);Key Research and Development Program of Shaanxi Province(2022NY-044);Key Technologies Demonstration of Animal Husbandry in Shaanxi Province(20221086)。; Bacterial or viral infections,such as Brucella,mumps virus,herpes simplex virus,and Zika virus,destroy immune homeostasis of the testes,leading to spermatogenesis disorder and infertility.Of note,recent research shows...; 关键词：DMRT1 SPERMATOGENESIS ORCHITIS Spry1 NF-κB

A scoping review of SARS-CoV-2 and male infertility: Concerns and future prospects: 《Asian pacific Journal of Reproduction》2022年第2期53-61,共9页Falah Hasan Obayes AL-Khikani Aalae Salman Ayit; Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has been detected in the blood,urine,facial/anal swabs,semen,and vaginal discharge;all have been shown to contain SARSCoV-2 RNA.Recent findings have highlight...; 关键词：INFERTILITY COVID-19 SARS-CoV-2 Male reproductive system CORONAVIRUS Genital tract abnormalities ORCHITIS

Isolated Autoimmune Orchitis Due to IgG4 Hypersecretion Presenting as Tumor-Like Mass: Case Report and Review of Literature: 《Open Journal of Urology》2022年第1期51-56,共6页Francisco Marcos da Silva Barroso Flavio Antunes de Sousa Paloma Menezes de Souza Gustavo Lopes de Castro Katia Ramos Moreira Leite Monique Freire Santana Roger Arthur da Cunha Alves Gabriela Ayumi Owada Borges Juan Eduardo Rios Rodriguez; Background: IgG4-related disease is a rare autoimmune condition that presents with lymphoplasmacytic infiltrate and fibrosis in the organ affected. Isolated testicle involvement is uncommon and there ...; 关键词：ORCHITIS IgG4-Related Disease AUTOIMMUNE TESTICLE INFLAMMATORY

Effect of ketotifen fumarate on experimental autoimmune orchitis and torsion of the spermatic cord被引量：4: 《Asian Journal of Andrology》2020年第1期112-117,共6页Diego Moreno Cristian M Sobarzo Livia Lustig Marcelo G Rodriguez Pena Vanesa Anabella Guazzone; This work was supported by grants from Found ation“Florencio Fiorini”;the University of Buenos Aires(UBACYT 2014-201722320160100058BA).; The aim of this work was to study effects of ketotifen fumarate(KF)on prevention of tissue damage in testes of rats with experimental autoimmune orchitis(EAO)and on the contralateral testis in a model of prolonged tes...; 关键词：KETOTIFEN FUMARATE male infertility MAST cells ORCHITIS TESTICULAR cord torsion TESTIS

Infectious Pathology of the Scrotum in Abidjan: Ultrasound Features of 80 Cases: 《Open Journal of Radiology》2017年第2期103-111,共9页N’goran Kouame Fotso Sorel Manewa Amlan Marie-France Kouame Anne-Marie N’goan-Domoua Roger-Daniel N’gbesso; Objectives: The aim of this study was to determine the epidemiological-clinical profile of patients with scrotal infectious pathology in Abidjan and describe the ultrasound features of this scrotal infectious patholog...; 关键词：ORCHITIS EPIDIDYMITIS Large BURSA Male GENITAL Infection

Mycotic Aneurysm of Infrarenal Aorta: A Case Report and Review of Literature: 《Journal of Biosciences and Medicines》2015年第3期88-93,共6页Irene S. Beltran-Ordonez Tay Seow Yian Ang Hou Eric Wong Ming Hai; Mycotic or infected aneurysms are focal vascular dilatations from inflammation or infection that results in weakening of the blood vessel wall. It poses a high risk of complications such as aneurysm rupture, uncontrol...; 关键词：MYCOTIC Aneurysm AORTA Peri-Aortic Epidymo-Orchitis PYELONEPHRITIS Percutaneous ENDOVASCULAR Repair (EVAR) with Covered ENDOVASCULAR Revascularization of Aortic Bifurcation (CERAB)

Coccidioidomycosis of the Testis and Epididymis: 《Open Journal of Urology》2013年第2期87-89,共3页Dane E. Klett Y. Mark Hong; This report describes an unusual presentation of a man with a testicular mass who presented in diabetic ketoacidosis to the emergency department. Initial diagnosis was a suspected testicular malignancy based on histor...; 关键词：COCCIDIOIDOMYCOSIS TESTICULAR Mass EPIDIDYMITIS ORCHITIS Valley FEVER

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