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作 者:Mahmoud Saad Mohamed El-Khodary
机构地区:[1]Department of Veterinary Medicine, Zagazig University, Zagazig, Egypt [2]Department of Fish Diseases Suez Canal University, Ismailia, Egypt [3]General Organization for Export and Import Control, Suez, Egypt
出 处:《CellBio》2018年第2期13-22,共10页细胞生物学(英文)
摘 要:Cancer is cell fleeing from death by blocking the intrinsic and extrinsic programs of cell death. The six elements that shut down those programs are: muc-1, muc-4, muc-16, Bcl-2, MMPs and decoy R3. The nuclear factor-kappa B (NF-Kb) stimulates the expression of genes responsible for the production of those elements, which are used by cells to block those two programs. In other words, the nuclear factor kappa B (NF-KB) is responsible for blocking both programs. Therefore, the nuclear factor kappa B (NF-Kb) is the true cause of cancer.Cancer is cell fleeing from death by blocking the intrinsic and extrinsic programs of cell death. The six elements that shut down those programs are: muc-1, muc-4, muc-16, Bcl-2, MMPs and decoy R3. The nuclear factor-kappa B (NF-Kb) stimulates the expression of genes responsible for the production of those elements, which are used by cells to block those two programs. In other words, the nuclear factor kappa B (NF-KB) is responsible for blocking both programs. Therefore, the nuclear factor kappa B (NF-Kb) is the true cause of cancer.
关 键 词:CANCER CAUSE MUC-1 Muc-4 Muc-16 Metalloprotenase Enzymes (MMPs) Bcl-2 Decoy-R3 NF-KB ANTI-APOPTOTIC Genes
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