Acknowledgement Project was supported by the National Natural Science Foundation of China (No 30570592, 30800334). The authors thank Dr BarryJ SESSLE. Professor of Oral Physiology, Faculty of Dentistry, University of Toronto, for his expert help in reviewing the manuscript.
Pain is a complex experience encompassing sensory-discriminative, affective-motivational and cognitiv e-emotional components mediated by different mechanisms. Contrary to the traditional view that the cerebral cortex ...
Recent studies have indicated that trigeminal neurons exhibit central sensitization, an increase in the excitability of neurons within the central nervous system to the extent that a normally innocuous stimulus begins...