This work was supported by the grants from the National Natural Science Foundation of China (Nos. 91129000, 11374207, 31370750, 21273148, 11405250 and 11074168), MOST (No. 2014YQ090709), the Science and Technology Commission of Shanghai Municipality (No. 15142201200), SJTU (No. YG2012MS58), and the K.C. Wong Education Foundation (H.K.).
There is presently a significant demand for instruments capable of determining the structures of large biological complexes. While room temperature atomic force microscopy (RT-AFM) has provided direct sub-nanometer ...
the National Basic Research Program(973) of China(No.2013CB932801);the National Natural Science Foundation of China(Nos.991129000,11374207,11375253,31370750,21273148 and 11074168);the Fund of Chinese Academy of Sciences(No.KJCX2-EW-N03)
High resolution structural studies of DNA and DNA binding proteins by atomic force microscopy(AFM) require well-bound samples on suitably flat substrates. Adsorbing the DNA onto a positively charged supported lipid bi...
the National Natural Science Foundation of China(Nos.991129000,11374207,31370750,21273148 and 11074168)
Bacterial pore-forming toxins(PFTs) are essential virulence factors of many human pathogens. Knowledge of their structure within the membrane is critical for an understanding of their function in pathogenesis and for ...
the National Natural Science Foundation of China(Nos.991129000,11374207,31370750,21273148 and 11074168)
Frequency-modulation atomic force microscopy(FM-AFM) is a highly versatile tool for surface science.Besides imaging surfaces, FM-AFM is capable of measuring interactions between the AFM probe and the surface with high...