目的研究细胞外信号调节激酶(extracellular signal-regulated protein kinase,ERK)对肿瘤坏死因子-α(TNF-α)诱导内皮细胞β-1,4-半乳糖基转移酶-I(β-1,4-GalT-I)表达的调节作用。方法用不同浓度的TNF-α刺激人脐静脉内皮细胞(human ...
This work was supported by grants from the National Natural Science Foundation of China (No. 30300099 and No. 30770488), Natural Science Foundation of Jiangsu Province (No. BK2003035 and No. BK2006547), College and University Natural Scientific Research Program of Jiangsu Province (No. 03KJB180109), "Ke-Jiao-Xing-Wei-Zhong-Dian-Yi-Xue-Ren-Cai" Financial Assistance of Jiangsu Province (No. RC2007087).
Background There are few reports of a biological role for glycosyltransferases in the infiltration of osteoarthritic synovitis. The aim of this research was to investigate the expression and cellular location of β-1,...
目的:研究细胞外信号调节激酶(extracellular signal-regulated protein kinase,ERK)对脂多糖(LPS)诱导内皮细胞β-1,4-半乳糖基转移酶-Ⅰ(β-1,4-galactosyltransferase-Ⅰ,β-1,4-GalT-Ⅰ)表达的调节作用。方法:应用ERK通路抑制剂U012...