国家自然科学基金(U1202228)

作品数：7被引量：44H指数：4
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相关期刊：《Zoological Research》《Science China(Life Sciences)》《Infectious Diseases of Poverty》《免疫学杂志》更多>>
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High seroprevalence of toxoplasma gondii and HIV-1 co-infection among drug users in Yunnan province, southwest China被引量：2
《Science China(Life Sciences)》2016年第8期857-859,共3页Xin Chen Mei Ye Yan-Heng Zhou Feng-Liang Liu Lin Duo Hong Li Wei Pang Yong-Tang Zheng 
supported by the National Natural Science Foundation of China(81271892,U1302224,U1202228);Key Scientific and Technological Program of China(2012ZX10001-006,2012ZX10001-007)
Dear Editor, Toxoplasma gondii was discovered more than 100 years ago and has a broad-spectrum of intermediate hosts in addi- tion to its definitive host, felids. Although it does not cause symptomatic illness in mos...
关键词：users TOXOPLASMA RETARDATION illness southwest infected likely PRONE children CONCLUSION 
Factors associated with needle sharing among people who inject drugs in Yunnan, China: a combined network and regression analysis被引量：3
《Infectious Diseases of Poverty》2016年第1期660-669,共10页Xin Chen Lin Zhu Yan-Heng Zhou Feng-Liang Liu Hong Li Zhi-Hong Yao Lin Duo Wei Pang Mei Ye Yong-Tang Zheng 
supported in part by grants from the National Natural Science Foundation of China(81271892,U1302224,U1202228);the Key Scientific and Technological Program of China(2012ZX10001-006,2012ZX10001-007)。
Background:Network analyses have been widely utilized to evaluate large datasets,but have not yet been used to explore factors associated with risk behaviours.In combination with traditional regression analysis,networ...
关键词：People who inject drugs Needle sharing Risk behaviours Network analysis Regression analysis China 
艾滋病猕猴模型的肠道病理学研究进展被引量：8
《免疫学杂志》2015年第3期265-269,276,共6页张琳萄 夏雪山 郑永唐 
国家自然科学基金(81172876,81273251,81471620,U1202228);国家重大科学研究计划课题(2012CBA01305);国家科技重大专项课题(2012ZX10001-007,2013ZX10001-002)
HIV是导致AIDS的病原体,HIV感染后会引起机体免疫缺陷并导致多个器官的损伤,其中肠道损伤是HIV感染后最常见的病变之一。肠道损伤既是HIV致病的直接诱因,也能间接地影响机体多项免疫功能进而加速疾病进展。非人灵长类动物在组织结构、...
关键词：AIDS SIV 灵长类动物 胃肠道 病理学变化 
Experimental primates and non-human primate(NHP) models of human diseases in China: current status and progress被引量：19
《Zoological Research》2014年第6期447-464,共18页Xiao-Liang ZHANG Wei PANG Xin-Tian HU Jia-Li LI Yong-Gang YAO Yong-Tang ZHENG 
supported by the National Natural Science Foundation of China(81172876,81273251,U1202228,81471620);the National Special Science Research Program of China(2012CBA01305);the National Science and Technology Major Project(2013ZX10001-002,2012ZX10001-007);the Knowledge Innovation Program of CAS(KSCX2-EW-R-13,KJZD-EW-L10-02)
Non-human primates （NHPs） are phylogenetically close to humans, with many similarities in terms of physiology, anatomy, immunology, as well as neurology, all of which make them excellent experimental models for biom...
关键词：Non-human primates Experimental primates Animal models Current status 
Flow cytometric characterizations of leukocyte subpopulations in the peripheral blood of northern pig-tailed macaques （Macaca leonina）被引量：4
《Zoological Research》2014年第6期465-473,共9页Hong-Yi ZHENG Ming-Xu ZHANG Lin-Tao ZHANG Xiao-Liang ZHANG Wei PANG Long-Bao LYU Yong-Tang ZHENG 
This work was supported by the National Special Science Research Program of China （2012CBA01305）; the National Natural Science Foundation of China （81172876, U0832601, 81273251, U1202228）; the Knowledge Innovation Program of CAS （KSCX2-EW-R-13） and the National Science and Technology Major Project （2013ZX10001-002, 2012ZX10001-007）We thank Mr. Zhen-Fei Hu,Gui Li and Dong-Ti Huang of Kunming Primate Research Center for their assistance with the experiments.
Pig-tailed macaques(Macaca nemistrina group) have been extensively used as non-human primate animal models for various human diseases in recent years, notably for AIDS research due to their sensitivity to HIV-1. North...
关键词：Northern pig-tailed macaque Flow cytometry Leukocyte subpopulation Age Sex 
Replication potentials of HIV-1/HSIV in PBMCs from northern pigtailed macaque （Macaca leonina）被引量：5
《Zoological Research》2014年第3期186-195,共10页Ai-Hua LEI Gao-Hong ZHANG Ren-Rong TIAN Jia-Wu ZHU Hong-Yi ZHENG Wei PANG Yong-Tang ZHENG 
Foundation items： This work was supported by the National Basic Research Program （2012CBA01305）; the National Natural Science Foundation of China （81172876, U0832601, 81273251 and U 1202228） the Knowledge Innovation Program of CAS （KSCX2-EW-R-13, Y206A- 71181）, and the Key Scientific and Technological Program of China （2012ZX10001-007, 2013ZX10001-002）. Acknowledgements： We thank Prof. Guang-Xia GAO （Institute of Biophysics, Chinese Academy of Sciences） for kindly providing HSIV proviral plasmids.We also thank Long-Bao LV, Gui LI and Dong- Ti HUANG of Kunming Primate Research Center for their assistance in obtaining blood samples from northem pig-tailed macaques （M. leonina） and Chinese rhesus macaques.
The northern pig-tailed macaque （Macaca leonina） has been identified as an independent species of Old World monkey, and we previously found that PBMCs from M. leonina were susceptible to human immunodeficiency virus...
关键词：HIV-1 HSIV REPLICATION PBMC Northern pig-tailed macaque （Macaca leonina） 
Analysis of immunoglobulin, complements and CRP levels in serum of captive northern pig-tailed macaques （Macaca leonina）被引量：8
《Zoological Research》2014年第3期196-203,共8页Xiao-Liang ZHANG Wei PANG De-Yao DENG Long-Bao LV Yue FENG Yong-Tang ZHENG 
Foundation items： This work was supported by the National Natural Science Foundation of China （81172876, U0832601, 81273251, U1202228）; the National Special Science Research Program of China （2012CBA01305）; the National Science and Technology Major Project （2013ZX10001-002, 2012ZX10001-007） and the Knowledge Innovation Program of CAS （KSCX2-EW-R-13）.
The northem pig-tailed macaque （NPM, Macaca leonina） has become a widely used animal model in biomedical research. In this study, we measured serum immunoglobulin IgG, IgM, IgA, complement C3, C4 and CRP levels in 3...
关键词：Northern pig-tailed macaque （Macaca leonina） IMMUNOGLOBULIN Complement C-reactive protein 
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