国家自然科学基金(81271821)

作品数：3被引量：36H指数：3
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Inducible Rubicon facilitates viral replication by antagonizing interferon production被引量：5
《Cellular & Molecular Immunology》2017年第7期607-620,共14页Yushun Wan Wei Cao Tao Han Sheng Ren Jian Feng TieLong Chen Jun Wang Ruth Broering Mengji Lu Ying Zhu 
the supporting of special funding for the PhD students of Wuhan University short-term study abroad;supported by research grants from the Major State Basic Research Development Program of China(2013CB911102);the National Natural Science Foundation of China(81461130019,81271821 and 31570870).
The RUN domain Beclin-1-interacting cysteine-rich-containing(Rubicon)protein is involved in the maturation step of autophagy and the endocytic pathway as a Beclin-1-binding partner,but little is known regarding the ro...
关键词：host response immune evasion INTERFERON RUBICON viral infection 
An Overview of the Highly Pathogenic H5N1 Influenza Virus被引量：9
《Virologica Sinica》2013年第1期3-15,共13页Jingchuan Yin Shi Liu Ying Zhu 
National Natural Science Foundation of China (30979144 and 81271821)
Since the first human case of H5N1 avian influenza virus infection was reported in 1997, this highly pathogenic virus has infected hundreds of people around the world and resulted in many deaths. The ability of H5N1 t...
关键词：Avian influenza H5N1 TRANSMISSION VIRULENCE PATHOGENESIS 
MicroRNA-548 down-regulates host antiviral response via direct targeting of IFN-λ1被引量：22
《Protein & Cell》2013年第2期130-141,共12页Yongkui Li Jiajia Xie Xiupeng Xu Jun Wang Fang Ao Yushun Wan Ying Zhu 
supported by research grants from the National Basic Research Program(973 Program)(Nos.2013CB911102,and 2009CB522506);National Mega Project on Major Infectious Diseases Prevention(2012ZX10004503);Na-tional Natural Science Foundation of China(Grant No.81271821).
Interferon(IFN)-mediated pathways are a crucial part of the cellular response against viral infection.Type III IFNs,which include IFN-λ1,2 and 3,mediate antiviral responses similar to Type I IFNs via a distinct recep...
关键词：microRNA-548 interferon-λ1 viral infec-tion antiviral response 
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