supported by the National Natural Science Foundation of China (No. 91129706);NSFC-Shandong Joint Fund (Nos. U1406402 and U1606403);National Key Technology R & D Program of the Ministry of Science and Technology (No. 2013BAB01B02);Taishan Scholar Special Fund of Shandong Province in China (G. Y. and L. Z.);the Major Science and Technology Projects of Shandong Province (No. 2015 ZDJS04002)
Fibroblast growth factor 19(FGF19) functions as a hormone by affecting glucose metabolism. FGF19 improves glucose tolerance when overexpressed in mice with impaired glucose tolerance or diabetes. A functional cellular...
supported by the National Natural Science Foundation of China(No.91129706);NSFCShandong Joint Fund(No.U1406402);Taishan Scholar Special Fund of Shandong Province in China(L.Z.)
Cardiovascular disease is the leading causes of death.However,the complications can be treated with heparin and heparinoids,such as heparin pentasaccharide Fondaparinux,dermatan sulfate,and PSS made from alginate extr...
supported by the National Natural Science Foundation of China (21171154 and 91129706);Special Fund for Marine Scientific Research in the Public Interest (01005024)
The pyrrole-derived alkaloids with marine origin, especially their permethyl derivatives, have unique structures and promising biological activities. Marine natural product neolamellarins are a collection of lamellari...
supported by the National Natural Science Foundation of China (Grant No. 91129706)
Land animals as well as all organisms in ocean synthesize sulfated polysaccharides. Fungi split from animals about 1.5 billion years ago. As fungi make the evolutionary journey from ocean to land, the biggest changes ...