supported by the National Natural Science Foundation of China(81371213,81070987,and30971531);the grants from the Ministry of Science and Technology of China(2010CB945600 and 2010CB945601)
Neuroplastin 65 (Np65) is an immunoglobulin superfamily cell adhesion molecule involved in synaptic formation and plasticity. Our recent study showed that Np65-knockout (KO) mice exhibit abnormal cognition and emo...
This study was supported by grants from State Key Laboratory of Medical Neurobiology, Fudan University, and the programs from the Ministry of Science and Technology of China (No. 2010CB945600 and No. 2011CB965100), the National Natural Science Foundation of China (No. 81070987, No. 30971531), Shanghai Science Foundation (No. 11PJ1407800), and National Education Ministry (IRT1168), International Science & Technology Collaboration Program (No. 2011DF30010).
Background Our previous studies have indicated that the beneficial effects of grafting neural stem cells (NSCs) overexpressing glial cell line-derived neurotrophic factor (GDNF) in rats after stroke. However, the ...
This study was supported by grants from the National Basic Research Program of China (2011 CB965300, 2009CB941100, 2010CB945600), the National Natural Science Foundation of China (31030050), Strategic Priority Research Program of CAS (XDA01000000), Science and Technology Committee of Shanghai Municipality (08DJ1400501), National Science and Technology Project of China (2012ZX09501-001-001), and Sanofi-Aventis Re- cherche & D6veloppement-SIBS funding. We thank Dr Duanqing Pei (Guangzhou Institutes of Biomedicine and Health, China) for kindly providing the miPSC lines iPS-C5 and iPS-C12.
Generation of induced pluripotent stem cells (iPSCs) has opened new avenues for the investigation of heart diseases, drug screening and potential autologous cardiac regeneration. However, their application is hamper...
supported by the National High Technology Research and Development Program of China(Grant No. 2006AA02Z474);the National Natural Science Foundation of China(Grant No. 30801115);the China Postdoctoral Science Foundation(Grant No. 20070410743);the National Basic Research Program of China(Grant No. 2010CB945600)
Functional human hepatocytes xenografted into the liver of mice can be used as a model system to study pharmacokinetics,infection of hepatitis viruses,and the efficacy of hepatitis vaccines.Significant levels of liver...
Mesenchymal stem cells (MSCs) have great potential for treating various diseases, especially those related to tissue damage involving immune reactions. Various studies have demonstrated that MSCs are strongly immuno...