国家重点基础研究发展计划(2011CB943802)

作品数：4被引量：1H指数：1
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The Sterile 20-Like Kinase Tao Controls Tissue Homeostasis by Regulating the Hippo Pathway in Drosophila Adult Midgut
《Journal of Genetics and Genomics》2014年第8期429-438,共10页Xudong Huang Lai Shi Jun Cao Fangfei He Renling Li Yan Zhang Shuang Miao Longjin Jin Jia Qu Zhouhua Li Xinhua Lin 
supported by the grants from the National Natural Science Foundation of China (Nos. 31271582 and 31030049);Wenzhou Medical University (No. XNK07005);Research Foundation for Advanced Talents of Wenzhou Medical College (No. QTJ08012);the National Basic Research Program of China (Nos. 2011CB943901, 2011 CB943902 and 2011CB943802);Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDA01010101)
The proliferation and differentiation of adult stem cells must be tightly controlled in order to maintain resident tissue homeostasis. Dysfunction of stem cells is implicated in many human diseases, including cancer. ...
关键词：Stem cell MIDGUT DROSOPHILA Tissue homeostasis TAO HIPPO 
Drosophila heparan sulfate 3-0 sulfotransferase B Null Mutant Is Viable and Exhibits No Defects in Notch Signaling
《Journal of Genetics and Genomics》2014年第7期369-378,共10页Yueqin Guo Ying Feng Zhouhua Li Xinhua Lin 
supported by the grants from the National Basic Research Program of China(Nos.2011CB943901,2011CB943902 and 2011CB943802);the National Natural Science Foundation of China(Nos.31030049,31271582 and 31071284);Strategic Priority Research Program of the Chinese Academy of Sciences Grant(No.XDA01010101)
Heparan sulfate proteoglycans （HSPGs） are critically involved in a variety of biological events. The functions of HSPGs are determined by the nature of the core proteins and modifications of heparan sulfate （HS） g...
关键词：DROSOPHILA heparan sulfate proteoglycans Hs3st-A Hs3st-B NOTCH 
dBrms1 Acts as a Positive Regulator of Notch Signaling in Drosophila Wing
《Journal of Genetics and Genomics》2014年第6期317-325,共9页Qinghai Zhang Yan Zhang Longfei Wu Yongfei Yang Xue Li Lei Gao Xiaomeng Hou Yihui Wu Guoli Hou Zhouhua Li Xinhua Lin 
supported by the grants from National Basic Research Program of China (Nos.2011CB943901, 2011CB943902 and 2011CB943802);the National Natural Science Foundation of China (Nos.31030049, 31271582 and 31071284);the Strategic Priority Research Program of the Chinese Academy of Sciences(No. XDA01010101)
The highly conserved Notch signaling is precisely regulated at different steps in a series of developmental events. However, little is known about the regulation of Notch receptor at transcriptional level. Here, we de...
关键词：Notch signaling DROSOPHILA Wing disc Notch transcription dBrmsl 
Maternal Mga is required for Wnt signaling and organizer formation in the early Xenopus embryo被引量：1
《Acta Biochimica et Biophysica Sinica》2012年第11期939-947,共9页Fei Gu Huijuan Shi Li Gao Haiyan Zhang Qinghua Tao 
Maternal Wntll is both necessary and sufficient for the formation of Spemann organizer in Xenopus embryo. Xnr3 and Siamois have been identified as the direct target genes of maternal Wntll/β-catenin during organizer ...
关键词：XENOPUS maternal genes Mga Wntpathway Spemann organizer TCF4 
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