XENOPUS

作品数:58被引量:80H指数:5
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相关领域:生物学更多>>
相关作者:刘青坡杨宝峰李宝馨李玉荣徐长庆更多>>
相关机构:华东师范大学中国科学院清华大学哈尔滨医科大学更多>>
相关期刊:《Science China(Life Sciences)》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金上海市自然科学基金更多>>
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Effects of triclosan adsorption on intestinal toxicity and resistance gene expression in Xenopus tropicalis with different particle sizes of polystyrene
《Journal of Environmental Sciences》2024年第12期176-185,共10页Zhuo Dai Zikai Wang Xinying Pan Li Zheng Yanbin Xu Qingxia Qiao 
supported by the National Natural Science Foundation of China(Nos.31802025,41977340,and 42277260).
Microplastics(MPs)are commonly found with hydrophobic contaminants in the water column and pose a serious threat to aquatic organisms.The effects of polystyrene microplastics of different particle sizes on the accumul...
关键词:POLYSTYRENE TRICLOSAN Xenopus-tropicalis Resistance genes Gut community 
Xenopus cell-free extracts and their applications in cell biology study
《Biophysics Reports》2023年第4期195-205,共11页Junjun Liu Chuanmao Zhang 
supported by a grant from NIH to J.L(1 SC3 GM132056);by grants from National Natural Science Foundation of China to CMZ(32130026 and 92254305)
Xenopus has proven to be a remarkably versatile model organism in the realm of biological research for numerous years,owing to its straightforward maintenance in laboratory settings and its abundant provision of ample...
关键词:XENOPUS Cell-free extract OOCYTE Egg EMBRYO MEIOSIS MITOSIS Spindle 
Genome-wide identification and spatiotemporal expression profiling of zinc finger SWIM domain-containing protein family genes
《Zoological Research》2023年第3期663-674,共12页Imtiaz Ul Hassan Hafiz Mamoon Rehman Ziran Liu Liangji Zhou Muhammad Kaleem Samma Chengdong Wang Zixin Rong Xufeng Qi Dongqing Cai Hui Zhao 
supported by the National Key R&D Program of China,Synthetic Biology Research(2019YFA0904500);Research Grants Council of Hong Kong(14119120,14112618,and CRF C5033-19E to H.Z.);Additional support was provided by the Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics,Chinese University of Hong Kong。
The biological function of the novel zinc-finger SWIM domain-containing protein family(ZSWIM)during embryonic development remains elusive.Here,we conducted a genome-wide analysis to explore the evolutionary processes ...
关键词:ZSWIM gene family XENOPUS Gene expression Phylogenetic analysis BIOINFORMATICS 
Xenopus GLP-1-based glycopeptides as dual glucagon-like peptide 1 receptor/glucagon receptor agonists with improved in vivo stability for treating diabetes and obesity被引量:1
《Chinese Journal of Natural Medicines》2022年第11期863-872,共10页LI Qiang YANG Qimeng HAN Jing LIU Xiaohan FU Junjie YIN Jian 
supported by the Fundamental Research Funds for the Central Universities(No.JUSRP51712B);the Natural Science Foundation of Xuzhou(No.KC19154);the Open Project Program of Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor,Ministry of Education,Guangxi Medical University(No.GKE-KF202006)。
Peptide dual agonists toward both glucagon-like peptide 1 receptor(GLP-1R)and glucagon receptor(GCGR)are emerging as novel therapeutics for the treatment of type 2 diabetes mellitus(T2DM)patients with obesity.Our prev...
关键词:Glucagon-like peptide-1 GLUCAGON DIABETES OBESITY O-GLCNACYLATION 
Diversification of amphioxus and vertebrate Cerberus protein function in modulating Nodal,BMP and Wnt signals被引量:1
《Marine Life Science & Technology》2020年第1期16-23,共8页Yan-Jun Zhang De-Li Shi 
This work was supported by the Centre National de la Recherche Scientifique(CNRS)and the Sorbonne University.
Cerberus is a multifunctional antagonist implicated in embryonic patterning through modulation of Nodal,BMP and Wnt signals.Although its function is largely conserved in chordates,certain activities have diverged,even...
关键词:AMPHIOXUS BMP CERBERUS CHORDATE NODAL Wnt XENOPUS 
Developmental expression of three prmt genes in Xenopus被引量:1
《Zoological Research》2019年第2期102-107,共6页Cheng-Dong Wang Xiao-Fang Guo Thomas Chi Bun Wong Hui Wang Xu-Feng Qi Dong-Qing Cai Yi Deng Hui Zhao 
supported by grants from the Research Grants Council of Hong Kong CUHK14167017,CUHK24100414 to H.Z.;the Shenzhen Innovation Committee of Science and Technology grants(JCYJ20150331101823691);Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research(2017B030301018)to Y.D
DEAR EDITOR Protein arginine methyltransferases (PRMTs)are involved in many cellular processes via the arginine methylation of histone or non-histone proteins.We examined the expression patterns of prmt4,prmt7,and prm...
关键词:DEVELOPMENTAL EXPRESSION PRMT GENES XENOPUS 
An ex vivo assay for screening glucocorticoid signaling disruption based on glucocorticoid-response gene transcription in Xenopus tails被引量:1
《Journal of Environmental Sciences》2018年第4期104-112,共9页Xiaoying Chen Yuanyuan Li Min Zhu Zhanfen Qin 
supported by the National Natural Science Foundation of China (No. 21377153);the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDB14040102)
There is a pressing need for developing in vivo or ex vivo assays to screen the glucocorticoid(GC) signaling disruption of chemicals. Thus, we aimed to establish an ex vivo assay for screening GC signaling disruptio...
关键词:Glucocorticoid signaling Glucocorticoid-response gene Xenopus laevis tail Dexamethasone Bisphenol A(BPA) 
Xenopus transgenic to screen candidate molecules favoring myelin repair
《Journal of Translational Neuroscience》2017年第1期36-40,共5页Abdelkrim Mannioui David Du Pasquier Bernard Zalc 
To facilitate live imaging of demyelination and remyelination, we have generated a Xenopus laevis transgenic line, MBP-GFP-NTR, allowing conditional ablation of myelinating oligodendrocytes. In this line, the proximal...
关键词:multiple sclerosis XENOPUS LAEVIS TRANSGENIC DEMYELINATION REMYELINATION Crispr/Cas9 oligodendrocyte gene editing 
Inhibition of the Na<sup>+</sup>/Ca<sup>2+</sup>Exchanger NCX<sub>1</sub>Expressed in <i>Xenopus</i>Oocyte by Glycyrrhizic Acid and Cyclophylin A
《Journal of Biosciences and Medicines》2017年第3期128-141,共14页Jan Laudenbach Yu Wang Beibei Xing Silvia Schwarz Yinfang Xu Quanbao Gu Wolfgang Schwarz 
The Na+/Ca2+ exchanger plays an important role in regulation of airway smooth muscle contraction by regulating intracellular calcium, and is a potential target for treatment of asthma. To test modulation of exchanger ...
关键词:Sodium-Calcium EXCHANGER Asthma Voltage Clamp Glycyrrhizic Acid Cyclophylin A 
Optimization of the T3-induced Xenopus metamorphosis assay for detecting thyroid hormone signaling disruption of chemicals被引量:3
《Journal of Environmental Sciences》2017年第2期314-324,共11页Xiaofang Yao Xiaoying Chen Yinfeng Zhang Yuanyuan Li Yao Wang Zongming Zheng Zhanfen Qin Qingdong Zhang 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB14040102);the National Natural Science Foundation of China(No.21377153)
T3-induced Xenopus metamorphosis is an ideal model for detecting thyroid hormone(TH)signaling disruption of chemicals. To optimize the T3-induced Xenopus assay and improve its sensitivity and reproducibility, we int...
关键词:Thyroid hormone signaling DISRUPTION Xenopus laevis T3 induction Morphological endpoints TH-response gene expression 
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