云南高校图书馆联盟文献共享服务平台- O-GLCNACYLATION

O-GLCNACYLATION: 作品数：34被引量：66H指数：5; 导出分析报告; 相关领域：生物学更多>>; 相关作者：靳倩李家大罗浑金张树菊宓文义更多>>; 相关机构：南通大学广东医科大学空军军医大学（第四军医大学）中南大学更多>>; 相关期刊：《National Science Review》《Acta Biochimica et Biophysica Sinica》《Burns & Trauma》《实验动物科学》更多>>; 相关基金：国家自然科学基金高等学校学科创新引智计划国家教育部博士点基金中国博士后科学基金更多>>

O-GlcNAcylation通过调节Rack1蛋白稳定性参与SHH型髓母细胞瘤的形成: 《中国肿瘤临床》2025年第2期55-63,共9页罗静雅高堂清杨檬檬杨海红; 四川省自然科学基金项目(编号:2022NSFSC0672);中国人民解放军西部战区总医院院管课题项目(编号:2021-XZYG-B15)资助。; 目的:研究O-GlcNAcylation调节蛋白激酶C受体1(receptor for activated C kinase 1,Rack1)的稳定性在SHH型髓母细胞瘤(SHH type medulloblastoma,SHH-MB)形成中的功能作用。方法:选取中国人民解放军西部战区总医院临床肿瘤标本库中分子...; 关键词：RACK1 O-GLCNACYLATION 细胞增殖 SHH-MB

Glut3 promotes cellular O-GlcNAcylation as a distinctive tumorsupportive feature in Treg cells: 《Cellular & Molecular Immunology》2024年第12期1474-1490,共17页Amit Sharma Garima Sharma Zhen Gao Ke Li Mutong Li Menglin Wu Chan Johng Kim Yingjia Chen Anupam Gautam Hong Bae Choi Jin Kim Jung-Myun Kwak Sin Man Lam Guanghou Shui Sandip Paul Yongqiang Feng Keunsoo Kang Sin-Hyeog Im Dipayan Rudra; YC was financially supported by the Dissertation Completion Award of the University of Georgia and American Lebanese Syrian Associated Charities(ALSAC)at St.Jude Children’s Research Hospital;AG acknowledges support by the High Performance and Cloud Computing Group at the Zentrum für Datenverarbeitung of the University of Tübingen,the state of Baden-Württemberg through bwHPC and the German Research Foundation(DFG)through grant no INST 37/935-1 FUGG,and the de.NBI Cloud within the German Network for Bioinformatics Infrastructure(de.NBI)and ELIXIR-DE(Forschungszentrum Jülich and W-de.NBI-001,W-de.NBI-004,W-de.NBI-008,W-de.NBI-010,W-de.NBI-013,W-de.NBI-014,W-de.NBI-016,W-de.NBI-022)for supporting the computational analysis carried out in this work.AS was supported by BrainKorea21 Plus scholarship from the National Research Foundation of Korea(NRF);This research,in part,was supported by the Basic Science Research Program(grant#4.24643.01)funded by the Ministry of Education,Korea,and NRF grants#RS-2023-00260454(AS)and RS-2024-00345575(SHI)funded by the Korea Ministry of Science and ICT(MSIT);DR is recipient of National Natural Science Foundation of China grant#32470980.; Regulatory T cells(Tregs)establish dominant immune tolerance but obstruct tumor immune surveillance,warranting context-specific mechanistic insights into the functions of tumor-infiltrating Tregs(TIL-Tregs).We show th...; 关键词：Regulatory T cells TREG GLUT3 O-GLCNACYLATION Treg metabolism

运动通过提高OGT依赖的O-GlcNAcylation促进骨生成: 《生命的化学》2024年第11期2152-2159,共8页赵青夏燕谢幸尔; 南通市基础科学研究项目(MSZ2022003)。; 运动/机械应力可以有效促进骨生成,进而预防骨质疏松疾病的发生,但其作用机制尚不完全明确。O-连接β-N-乙酰氨基葡萄糖(O-linkedβ-N-acetylglucosamine,O-GlcNAc)糖基化修饰(O-GlcNAc glycosylation modification,O-GlcNAcylation)是...; 关键词：运动机械应力 OGT 糖基化修饰骨生成

Rapid and large-scale glycopeptide enrichment strategy based on chemical ligation: 《National Science Review》2024年第11期142-153,共12页Yingying Xiong Zhuoer Lu Yuyin Shao Peiyi Meng Guoli Wang Xinwen Zhou Jun Yao Huimin Bao Haojie Lu; supported by the National Key Research and Development Program of China(2023YFF1205900);the National Natural Science Foundation of China(22434001 and 82121004);the Shanghai Science and Technology Program(2023SHZDZX02,22DZ2291700 and 22142202400).; Protein glycosylation,the most universal post-translational modification,is thought to play a crucial role in regulating multiple essential cellular processes.However,the low abundance of glycoproteins and the heterog...; 关键词：GLYCOPROTEOMICS large-scale enrichment O-GLCNACYLATION N-GLYCOSYLATION oxidative stress

Senegenin suppresses hepatocellular carcinoma by regulating O-GlcNAcylation被引量：1: 《World Journal of Gastrointestinal Oncology》2024年第9期3994-4005,共12页Xiang Zhang Li-Qiong Wang Zhi-Yong Liu; BACKGROUND Based on current knowledge,hepatocellular carcinoma(HCC)is a condition with numerous etiologies and risk factors.However,the pathogenesis of HCC remains unclear.AIM To investigate the roles of senegenin and...; 关键词：SENEGENIN O-GLCNACYLATION Liver cancer PATHOGENESIS METASTASIS

O-GlcNAcylation determines the function of the key O-GalNAc glycosyltransferase C1GalT1 in bladder cancer被引量：1: 《Acta Biochimica et Biophysica Sinica》2024年第8期1108-1117,共10页Yazhuo Jiang Jinpeng Wu Feng Guan Liang Liang Yili Wang; supported by the grant from the Science and Technology Development of Shaanxi Province,China(No.2023-YBSF-004).; Protein glycosylation is a type of protein post-translational modification.One specific example is the modification of proteins with O-linkedβ-N-acetylglucosamine(O-GlcNAc)and O-linkedα-N-acetylgalactosamine(O-GalNA...; 关键词：C1GalT1 O-GlcNAc modification bladder cancer T antigen

O-GlcNAcylation对抗癌治疗效果的影响及其机制: 《生命科学》2024年第6期818-830,共13页马斌媛高宏伟尤崇革潘云燕; 国家自然科学基金面上项目(81972498);甘肃省自然科学基金项目(23JRRA1634)。; O-连接-N-乙酰氨基葡萄糖化(O-linkedβ-N-acetylglucosamine,O-GlcNAcylation)是蛋白质翻译后修饰(protein translation modifications,PTMs)的一种,调节各种基本的细胞生物学过程,包括基因转录、信号转导、应激反应和细胞代谢等。目前...; 关键词：O-GLCNACYLATION O-GlcNAc转移酶抗癌治疗耐药化疗耐药翻译后修饰

O-GlcNAcylation mediates H_(2)O_(2)-induced apoptosis through regulation of STAT3 and FOXO1被引量：1: 《Acta Pharmacologica Sinica》2024年第4期714-727,共14页Chen-chun Zhang Yuan Li Chang-you Jiangv Qiu-min Lev Xing Liu Lan Ma Fei-fei Wang; supported by grants from the National Natural Science Foundation of China(32222033 to FFW,32330041 and 31930046 to LM,32271064 to CYJ,32270660 to QML,32171041 to XL);the Science Technology Innovation 2030 Project of China(2021ZD0203500 to FFW and LM,2021ZD0202104 to XL,2022ZD0214500 to CYJ);the CAMS Innovation Fund for Medical Sciences(2021-I2M-5-009 to LM and XL).; The O-linked-β-N-acetylglucosamine (O-GlcNAc) glycosylation (O-GlcNAcylation) is a critical post-translational modification that couples the external stimuli to intracellular signal transduction networks. However, th...; 关键词：O-GLCNACYLATION oxidative stress APOPTOSIS STAT3 FOXO1

O-linkedβ-N-acetylglucosaminylation may be a key regulatory factor in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells: 《World Journal of Stem Cells》2024年第3期228-231,共4页Xu-Chang Zhou Guo-Xin Ni; Cumulative evidence suggests that O-linkedβ-N-acetylglucosaminylation(OGlcNAcylation)plays an important regulatory role in pathophysiological processes.Although the regulatory mechanisms of O-GlcNAcylation in tumors ...; 关键词：O-GLCNACYLATION Osteogenic differentiation Bone marrow mesenchymal stromal cells OSTEOPOROSIS

Protein O-GlcNAcylation homeostasis regulates facultative heterochromatin to fine-tune sog-Dpp signaling during Drosophila early embryogenesis被引量：1: 《Journal of Genetics and Genomics》2023年第12期948-959,共12页Yaowen Zhang Haibin Yu Dandan Wang Xiaoyun Lei Yang Meng Na Zhang Fang Chen Lu Lv Qian Pan Hongtao Qin Zhuohua Zhang Daan M.F.van Aalten Kai Yuan; This project has been supported by the National Natural Science Foundation of China(grants 91853108,92153301,31771589,and 32170821 to K.Y,32101034 to F.C);Department of Science and Technology of Hunan Province(grants 2017RS3013,2017XK2011,2018DK2015,2019SK1012,and 2021JJ10054 to K.Y,and the innovative team program 2019RS1010);Central South University(2018CX032 to K.Y,2019zzts046 to Y.Z,2019zzts339 to X.L,2021zzts497 to H.Y,and the innovation-driven team project 2020CX016);D.M.F.v.A.is supported by Wellcome Trust Investigator Award(110061);a Novo Nordisk Foundation Laureate award(NNF21OC0065969).; Protein O-GlcNAcylation is a monosaccharide post-translational modification maintained by two evolutionarily conserved enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Mutations in human OGT have recently be...; 关键词：Protein O-GlcNAcylation DROSOPHILA Early embryogenesis Polycomb repressive complex Facultative heterochromatin Neurodevelopment sog

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