SENEGENIN

作品数：6被引量：34H指数：4
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相关领域：医药卫生生物学更多>>
相关作者：张兴旺高玲玲刘文哲高玲玲更多>>
相关机构：榆林职业技术学院榆林市第一医院西北大学更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《Neural Regeneration Research》《分子植物育种》《Journal of Integrative Plant Biology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金北京市自然科学基金更多>>
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Senegenin suppresses hepatocellular carcinoma by regulating O-GlcNAcylation
《World Journal of Gastrointestinal Oncology》2024年第9期3994-4005,共12页Xiang Zhang Li-Qiong Wang Zhi-Yong Liu 
BACKGROUND Based on current knowledge,hepatocellular carcinoma(HCC)is a condition with numerous etiologies and risk factors.However,the pathogenesis of HCC remains unclear.AIM To investigate the roles of senegenin and...
关键词：SENEGENIN O-GLCNACYLATION Liver cancer PATHOGENESIS METASTASIS 
皂苷元在远志不同部位的含量分布及其动态变化研究被引量：4
《分子植物育种》2019年第15期5131-5135,共5页高玲玲 刘文哲 张兴旺 
榆林市科技计划项目(2016CXY-15-5)资助
本研究应用HPLC法对远志不同器官和不同发育时期皂苷元含量分布及其随季节的动态变化进行了分析、比较。研究结果表明:(1)远志皮部(次生韧皮部)、根木质部、茎、叶、花以及种子中都含有皂苷元,其在皮部含量最高,其它部位含量依次为叶>种...
关键词：皂苷元(Senegenin) 远志(Polygala tenuifolia) HPLC法 含量分布 动态变化 
Effects of Senegenin against Hypoxia/Reoxygenation-Induced Injury in PC12 Cells被引量：7
《Chinese Journal of Integrative Medicine》2016年第5期353-361,共9页朱小青 李学敏 赵严冬 纪惜銮 王彦平 付咏梅 王华东 陆大祥 戚仁斌 
Supported by the Natural Science Foundation of Guangdong Province,China(No.2014A030313394);the Project of Science and Technology of Guangzhou,China(No.2014J4100098);the National Program on Key Basic Research Project(973 Program,No.2011CB707501);the Fundamental Research Funds for the Central Universities in China(No.21613401)
Objective： To investigate the effect and the potential mechanism of Senegenin （Sen） against injury induced by hypoxia/reoxygenation （H/R） in highly differentiated PC12 cells. Methods： The cultured PC12 cells wer...
关键词：SENEGENIN hypoxiaJreoxygenation PC12 cells reactive oxygen species NAPDH oxidase 
Senegenin inhibits neuronal apoptosis after spinal cord contusion injury被引量：7
《Neural Regeneration Research》2016年第4期657-663,共7页Shu-quan Zhang Min-fei Wu Rui Gu Jia-bei Liu Ye Li Qing-san Zhu Jin-lan Jiang 
supported by a grant from the Science and Technology Development Plan of Jilin Province of China,No.2011084
Senegenin has been shown to inhibit neuronal apoptosis,thereby exerting a neuroprotective effect.In the present study,we established a rat model of spinal cord contusion injury using the modified Allen＇s method.Three...
关键词：nerve regeneration spinal cord contusion senegenin thinleaf milkwort root motor function apoptosis electrophysiology neural regeneration 
Senegenin promotes in vitro proliferation of human neural progenitor cells被引量：5
《Neural Regeneration Research》2011年第3期171-176,共6页Shi, Fang Liang, Zhigang Guo, Zixuan Li, Ran Yu, Fen Zhang, Zhanjun Wang, Xuan Wang, Xiaomin 
the National Basic Research Program of China-973 Project,No. 2006CB500700;the National Natural Science Foundation of China,No. 30500255;the Natural Science Foundation of Beijing,No. 5102010
Senegenin, an effective component of Polygala tenuifolia root extract, promotes proliferation and differentiation of neural progenitor cells in the hippocampus. However, the effects of senegenin on mesencephalon-deriv...
关键词：SENEGENIN neural progenitor cells cell proliferation mitogen-activated protein kinases 
Localization and Dynamic Change of Saponin in Vegetative Organs of Polygala tenuifolia被引量：11
《Journal of Integrative Plant Biology》2009年第6期529-536,共8页Hong-Mei Teng Min-Feng Fang Xia Cai Zheng-Hai Hu 
Funded Projects of Independent Innovation of NorthwestUniversity Postgraduates (07YZZ25);the Shaanxi Provincial NaturalScience Foundation (SJ08-ZT02)
Anatomical, histochemical and phytochemical methods were used to investigate the structure, localization and dynamic changes of total saponin and senegenin of vegetative organs in Polygala tenuifolia Willd. Histochemi...
关键词：dynamic change LOCALIZATION Polygala tenuifolia SAPONIN SENEGENIN STRUCTURE vegetative organs. 
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