云南高校图书馆联盟文献共享服务平台- RACK1

RACK1: 作品数：106被引量：212H指数：7; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：万莉红王庆阳吴非翁长江汪宇辉更多>>; 相关机构：四川大学扬州大学安徽医科大学复旦大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划广东省医学科学技术研究基金陕西省自然科学基金更多>>

冠状病毒核衣壳蛋白促进核孔蛋白解聚和拮抗先天免疫反应的机制研究: 《中国兽医科学》2025年第2期283-284,共2页《中国兽医科学》编辑部廖瑛(审核); 冠状病毒能够有效逃避宿主天然免疫应答,这是其感染过程中的显著特征。天然免疫信号通路的激活依赖多个启动抗病毒基因表达的转录因子进入细胞核,而这一过程需要宿主核质运输系统的协助,因此,该系统成为冠状病毒拮抗宿主免疫反应的关键...; 关键词：冠状病毒(coronavirus) 核衣壳蛋白(nucleocapsid protein N蛋白) RACK1-PKC复合物核孔蛋白磷酸化核孔复合体解聚核质运输转录因子

O-GlcNAcylation通过调节Rack1蛋白稳定性参与SHH型髓母细胞瘤的形成: 《中国肿瘤临床》2025年第2期55-63,共9页罗静雅高堂清杨檬檬杨海红; 四川省自然科学基金项目(编号:2022NSFSC0672);中国人民解放军西部战区总医院院管课题项目(编号:2021-XZYG-B15)资助。; 目的:研究O-GlcNAcylation调节蛋白激酶C受体1(receptor for activated C kinase 1,Rack1)的稳定性在SHH型髓母细胞瘤(SHH type medulloblastoma,SHH-MB)形成中的功能作用。方法:选取中国人民解放军西部战区总医院临床肿瘤标本库中分子...; 关键词：RACK1 O-GLCNACYLATION 细胞增殖 SHH-MB

Rack1 regulates B-cell development and function by binding to and stabilizing the transcription factor Pax5: 《Cellular & Molecular Immunology》2024年第11期1282-1295,共14页Xueting Zhang Chenke Ma Yuchen Lu Jing Wang Hongfang Yun Hui Jiang Mengyao Wu Xiaoyao Feng Wenbin Gai Guanglei Xu Hongbin Deng Jiannan Feng Wanli Liu Taoxing Shi Qianqian Cheng Jiyan Zhang; supported by grants from the National Natural Science Foundation of China(81930027,92169207,and 82172298).; The transcription factor Pax5 activates genes essential for B-cell development and function.However,the regulation of Pax5 expression remains elusive.The adaptor Rack1 can interact with multiple transcription factors ...; 关键词：RACK1 PAX5 UBIQUITINATION B-cell development BCR signaling

Identification of RACK1 as a novel regulator of non-structural protein 4 of chikungunya virus: 《Acta Biochimica et Biophysica Sinica》2024年第10期1425-1436,共12页Yao Yan Fengyuan Zhang Meng Zou Hongyu Chen Jingwen Xu Shuaiyao Lu Hongqi Liu; supported by the grants from the Yunnan Key R&D Project(No.202103AQ100001);the Foundation of the CAMS Initiative for Innovative Medicine(Nos.2021-I2M-1-036 and 2021-I2M-1-043);the Fundamental Research Funds for the Central Universities(No.3332022072).; Chikungunya virus(CHIKV)is a neglected arthropod-borne and anthropogenic alphavirus.Over the past two decades,the CHIKV distribution has undergone significant changes worldwide,from the original tropics and subtropics...; 关键词：Chikungunya virus non-structural protein 4 RACK1 ubiquitin-proteasome pathway

呼吸道合胞病毒基质蛋白通过关联RACK1抑制干扰素信号传导: 《微生物学免疫学进展》2024年第4期95-95,共1页张晓昕(摘) 张英(校); 呼吸道合胞病毒(RSV)是儿童和老年人呼吸道疾病的常见病因,这种病毒的毒力与机体的免疫应答(尤其是I型IFN的产生)一定程度上共同决定了呼吸道疾病的严重程度。本研究使用蛋白质组学技术,在RSV感染的细胞中瞬时表达基质蛋白M,鉴定发现了...; 关键词：呼吸道疾病固有免疫应答常见病因 M蛋白基质蛋白信号传导伴侣蛋白干扰素

RACK1A promotes hypocotyl elongation by scaffolding light signaling components in Arabidopsis被引量：2: 《Journal of Integrative Plant Biology》2024年第5期956-972,共17页Yajuan Fu Wei Zhu Yeling Zhou Yujing Su Zhiyong Li Dayan Zhang Dong Zhang Jinyu Shen Jiansheng Liang; supported by grants from National Natural Science Foundation of China(32070292 to J.L.);Shenzhen Science and Technology Program(KQTD20190929173906742 to J.L.);The Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes(2019KSYS006 to J.L.);Scientific Research Funding for postdoctoral researchers staying at Shenzhen(K19227561,K21227504 to W.Z.).; Plants deploy versatile scaffold proteins to intricately modulate complex cell signaling.Among these,RACK1A(Receptors for Activated C Kinase 1A)stands out as a multifaceted scaffold protein functioning as a central in...; 关键词：ARABIDOPSIS hypocotyl development light signaling components RACK1 scaffoldprotein

The roles of RACK1 in the pathogenesis of Alzheimer's disease被引量：1: 《Journal of Biomedical Research》2024年第2期137-148,共12页Wenting He Xiuyu Shi Zhifang Dong; supported by grants from the National Natural Science Foundation of China(Grant No.82071395);the Natural Science Foundation of Chongqing(Grant Nos.cstc2021ycjh-bgzxm0186,cstc2020jcyj-zdxmX0004,and cstc2021jcyj-bsh0023);the CQMU Program for Youth Innovation in Future Medicine(Grant No.W0044).; The receptor for activated C kinase 1(RACK1)is a protein that plays a crucial role in various signaling pathways and is involved in the pathogenesis of Alzheimer's disease(AD),a prevalent neurodegenerative disease.RAC...; 关键词：RACK1 Alzheimer's disease PKC amyloid-β synaptic plasticity NEUROINFLAMMATION

Loss of DJ-1 function contributes to Parkinson’s disease pathogenesis in mice via RACK1-mediated PKC activation and MAO-B upregulation被引量：2: 《Acta Pharmacologica Sinica》2023年第10期1948-1961,共14页Le-le Liu Yu Han Zi-jia Zhang Yi-qi Wang Yu-wei Hu Elena Kaznacheyeva Jian-qing Ding Dong-kai Guo Guang-hui Wang Bin Li Hai-gang Ren; supported by the National Natural Science Foundation of China(Nos.32170987,31970966 and 32261133525);the Russian Science Foundation(No.23-44-00054);the Natural Science Foundation of Jiangsu Province(BK20200213);a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.; Parkinson’s disease (PD) is a common neurodegenerative motor disorder characterized by a dramatic reduction in pars compacta of substantia nigra dopaminergic neurons and striatal dopamine (DA) levels. Mutations or de...; 关键词：Parkinson’s disease DJ-1 MAO-B EGR1 RACK1 PKC

活化蛋白激酶C受体1在宫颈鳞状细胞癌中的表达及其与PI3K/Akt/mTOR信号转导通路关系的研究: 《医学信息》2023年第17期107-110,共4页王瑞才朱建友; 目的探讨PI3K/Akt/mTOR信号转导通路蛋白及RACK1在宫颈鳞状细胞癌中的表达及意义,以及与临床病理参数间的关系。方法选取2014年1月-2020年12月淄博市市立医院59例宫颈鳞癌组织及45例非肿瘤宫颈组织,用链霉亲和素-过氧化物酶免疫组化染...; 关键词：RACK1 PI3K Akt MTOR 宫颈鳞癌

口腔鳞癌组织中RACK1与EGP40的表达及其与临床病理特征及预后的相关性: 《上海口腔医学》2023年第4期385-390,共6页段咏华吴开柳梅健周谊渊刘梦石; 江西省自然科学基金(2019864)。; 目的探讨口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)癌组织中活性蛋白激酶C受体1(activated protein kinase C receptor 1,RACK1)与上皮糖蛋白40(epithelin glycoprotein 40,EGP40)的表达及其与临床病理特征及预后的关系。方...; 关键词：口腔鳞癌活性蛋白激酶C受体1 上皮糖蛋白40 病理特征预后

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