Financial support of the National Natural Science Foundation (Nos.81102461,81021062,and 90813034);National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"(Nos.2012ZX09301001-001 and 2012ZX09103101-024);the Shanghai Science and Technology Commission(Nos.11431921100 and 12DZ1930802)
The natural product,1,7-dimethoxy-2-hydroxyxanthone(1),isolated from Securidaca inappendiculate Hassk,has a potential in the treatment of erectile dysfunction due to its significant relaxation activity on rabbit Cor...
supported in part by the Ministry of Science and Technology of China(Grant Nos. 2006CB910104,2006AAZ105 and 2009CB918404);the National Natural Science Foundation of China(Grant Nos. 30630034,90813034 and 81071668);the Shanghai Science and Technology Commission(Grant Nos. 08JC1413700 and 07QA14041);the Shanghai Municipal Education Commission(Grant No. E09013)
Apoptosis,or programmed cell death,is a complex,genetically-determined process involved in the development and maintenance of homeostasis in multicellular organisms.Dysregulation of apoptosis has been implicated in a ...
Supported in part by the National High Technology Research and Development Program of China (Grant No. 2008AA02Z301);National Key Basic Research and Development Program of China (Grant Nos. 2009CB918400 and 2002CB512800);National Natural Science Foundation of China (Grant Nos. 90813034, 30500215, 30600216, and 30800452);Knowledge Innovation Project of the Chinese Academy of Sciences (Grant No. KSCX2-YW-R-097);the Shanghai Committee of Science and Technology, China (Grant Nos. 08JC1413700 and 08JC1413500)
Acute myeloid leukemia (AML) is a heterogeneous group of hematopoietic malignancies which are characterized by the blockage of hematopoietic cell differentiation with uncontrolled proliferation and/or impaired apoptos...