国家自然科学基金(81274159)

作品数:5被引量:69H指数:4
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相关作者:徐晓军吴蒙谢治深更多>>
相关机构:中国药科大学更多>>
相关期刊:《药学进展》《Chinese Journal of Natural Medicines》《生物质化学工程》更多>>
相关主题:INSULIN_RESISTANCE药理作用化学成分迷迭香RESTORE更多>>
相关领域:医药卫生更多>>
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天然小分子化合物改善糖尿病肾病的研究进展被引量:5
《药学进展》2017年第10期742-748,共7页钟羚君 谢治深 徐晓军 
国家自然科学基金资助项目(No.81274159)
糖尿病肾病是糖尿病严重并发症之一。从天然有机产物结构出发,根据已报道的相关作用机制,结合其化学结构,综述黄酮类、酚酸类、生物碱类和苷类等天然小分子化合物改善糖尿病肾病的研究进展,以期为寻找高效、低毒的治疗糖尿病肾病的先导...
关键词:糖尿病肾病 天然产物 黄酮类化合物 酚酸类化合物 生物碱类化合物 
Moutan Cortex and Paeoniae Radix Rubra reverse high-fat-diet-induced metabolic disorder and restore gut microbiota homeostasis被引量:15
《Chinese Journal of Natural Medicines》2017年第3期210-219,共10页ZHONG Ling-Jun XIE Zhi-Sheng YANG Hua LI Ping XU Xiao-Jun 
supported by the Fund for Creative Research Groups of China,National Natural Science Foundation of China(No.81421005);the Specialized Research Fund of the Doctoral Program of Higher Education(SRFDP);Research Council Earmarked Research Grants(RCERG)(No.201300 96140001);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);partially supported by the National Natural Science Foundation of China(No.81274159);supported by New Century Excellent Talents in University(NCET-12-0976)
The present study was designed to investigate the therapeutic effcts of Moutan Cortex(CM,root bark of Paeonia suffruticosa Andr) and Paeoniae Radix Rubra(PR,root of Paeonia veitchii Lynch) on metabolic disorders,focus...
关键词:Moutan Cortex Paeoniae Radix Rubra Insulin resistance Gut microbiota 
Petroleum ether sub-fraction of rosemary extract improves hyperlipidemia and insulin resistance by inhibiting SREBPs被引量:3
《Chinese Journal of Natural Medicines》2016年第10期746-756,共11页XIE Zhi-Shen ZHONG Ling-Jun WAN Xiao-Meng LI Meng-Ning YANG Hua LI Ping XU Xiao-Jun 
supported by the Funds for Creative Research Groups of China;National Natural Science Foundation of China(No.81421005);National Natural Science Foundation of China(No.81274159)
As a culinary and medicinal herb, rosemary is widely used. The present work aimed to investigate the effects of rosemary extracts on metabolic diseases and the underlying mechanisms of action. Liver cells stably expre...
关键词:ROSEMARY SREBPs HYPERLIPIDEMIA Insulin resistance 
迷迭香化学成分及药理作用最新研究进展被引量:36
《生物质化学工程》2016年第3期51-57,共7页吴蒙 徐晓军 
国家自然科学基金资助项目(81274159)
综述了迷迭香的化学成分和药理作用的最新研究进展(2011~2015年),简述了其性状及加工方法。迷迭香作为使用价值丰富的唇形科植物,主要化学成分有迷迭香精油、鼠尾草酸、鼠尾草酚、迷迭香酸等,药理作用包括抗菌、抗氧化、抗抑郁、代谢...
关键词:迷迭香 化学成分 药理作用 
Chemical profiling of Jinqi Jiangtang tablets by HPLC-ESI-Q-TOF/MS被引量:10
《Chinese Journal of Natural Medicines》2014年第3期229-240,共12页SUN Shi XIE Zhi-Shen LIU E-Hu YAN Yu-Ting XU Xiao-Jun LI Ping 
supported by the National Natural Science Foundation of China(No.81274159);"Eleventh-Five Years"Supporting Programs from the Ministry of Science and Technology of China(No.2008BAI51B01)
AIM: To profile the chemical constituents in Jinqi Jiangtang tablets. METHOD: Based on the chromatographic retention behavior, fragmentation patterns of chemical components, and published lit- eratures, a high-perfo...
关键词:HPLC-ESI-Q-TOF/MS Coptidis Rhizoma Astragali Radix Lonicerae Japonicae Flos Jinqi Jiangtang tablets MASSSPECTROMETRY 
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