国家自然科学基金(20030708)

作品数：2被引量：5H指数：1
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相关期刊：《Chemical Research in Chinese Universities》更多>>
相关主题：AROMATICADEPTPRODRUGGLYCOSYLATIONDERIVATIVE更多>>
相关领域：医药卫生生物学轻工技术与工程更多>>
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Increased Sensitivity of Porcine ΔF508-CFTR Chloride Channel to Specific Small Molecule CFTR Inhibitors
《Chemical Research in Chinese Universities》2009年第4期497-499,共3页ZHAO Hai-feng YU Ting LIU Xin LIU Rui ZHENG Lan SONG Li-na JIA Li YANG Hong HE Cheng-yan 
Supported by the General Administration of Quality Supervision,Inspection and Quarantine of China(No.2006IK145);the Natural Science Foundation of Jilin Province,China(Nos.200705269 and 20030708);the Natural Science Foundation of Changchun City,China(No.2007sf19);the Science and Technology Fund from the Education Department of Liaoning Province,China(No.20060492)
Deletion of the codon encoding the phenylalanine residue at position 508（ΔF508） in the cystic fibrosis transmembrane conductance regulator（CFTR） is the most common mutation causing cystic fibrosis（CF）.The human...
关键词：ΔF508-CFTR Pig CFTR INHIBITOR Cystic fibrosis 
Design and Synthesis of Glycosylated Aromatic Nitrogen Mustard Derivatives被引量：5
《Chemical Research in Chinese Universities》2007年第3期300-302,共3页LIU Tie-mei WANG Shu-sheng ZHU Guang-ze LI Ming-yang ZHANG Li-ping 
Supported by the National Natural Science Foundation of China(No20030708);the Natural Science Foundation of JinlinProrince, P R China(No20050702-4)
Antibody-directed enzyme prodrug therapy（ADEPT） is a new strategy for the treatment of cancer that has arisen in recent twenty years, the main merits of which are that it can improve the selectivity of anticancer dr...
关键词：GLYCOSYLATION Nitrogen mustard derivative PRODRUG ADEPT 
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