国家自然科学基金(81330031)

作品数:10被引量:24H指数:3
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相关作者:黄楠游天雪王昭朱晓华陈华东更多>>
相关机构:西南交通大学更多>>
相关期刊:《材料导报》《Chinese Journal of Chemical Physics》《材料科学与工程学报》《Regenerative Biomaterials》更多>>
相关主题:MAGNESIUMSTENTMAGNESIUM-BASED力学性能STENTS更多>>
相关领域:金属学及工艺一般工业技术医药卫生电子电信更多>>
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A“built-up”composite film with synergistic functionalities on Mg-2Zn-1Mn bioresorbable stents improves corrosion control effects and biocompatibility
《Bioactive Materials》2023年第7期223-238,共16页Zhenglong Dou Shuiling Chen Jiacheng Wang Li Xia Manfred F.Maitz Qiufen Tu Wentai Zhang Zhilu Yang Nan Huang 
This work was supported by the National Natural Science Foundation of China(Project 32171326,82072072,81330031);the INTERNATIONAL COOPERATION Project by Science and Technology Department of Sichuan Province(2021YslnFH0056);the High-level Talents Research and Development Program of Affiliated Dongguan Hospital(K202102).
Control of premature corrosion of magnesium(Mg)alloy bioresorbable stents(BRS)is frequently achieved by the addition of rare earth elements.However,limited long-term experience with these elements causes concerns for ...
关键词:Magnesium alloys Bioresorbable stents Composite coating Corrosion control BIOCOMPATIBILITY 
基于共价固定高密度透明质酸构建具有抗菌抗凝血双功能的表面被引量:4
《材料导报》2020年第8期165-171,共7页马文梅 黄楠 熊开琴 
国家自然科学基金重点项目(81330031)。
表面血栓生成和细菌感染是导致体外血液循环装置及留置器械等血液接触类器材失效的重要原因,表面接枝生物活性分子是赋予材料表面抗血栓及抗菌性能的重要手段。然而,现有的抗菌抗凝血双功能改性方法通常基于复杂的改性策略并难以良好地...
关键词:透明质酸 表面改性 抗凝血 抗菌 
医用可降解Zn-Cu合金的力学性能和腐蚀性能被引量:3
《材料科学与工程学报》2019年第1期51-55,共5页唐馨 李浩 游天雪 罗竹 黄楠 
国家自然科学基金资助项目(81330031)
通过在纯锌中加入Cu元素以提高医用可降解Zn-Cu合金的力学性能,研究Cu元素含量的变化对Zn-Cu合金力学性能和耐腐蚀性能的影响。通过熔炼制备了铸态Zn-x wt.%Cu(x=0,1,1.5,2,2.5)合金,采用金相分析、拉伸试验和硬度测试分析其组织结构和...
关键词:可降解金属 锌铜合金 力学性能 耐腐蚀性能 
In vitro and in vivo cytocompatibility evaluation of biodegradable magnesium-based stents: a review被引量:1
《Science China Materials》2018年第4期501-515,共15页Ping Li Ningling Zhou Hua Qiu Manfred F Maitz Juan Wang Nan Huang 
supported by the National Natural Science Foundation of China (31600766, 21473138 and 81330031);the Fundamental Research Funds for the Central Universities (No. 2682016CX076)
Biodegradable magnesium(Mg)-based vascular stents have been designed as temporary scaffolds to treat angiostenotic lesions for the maintenance of normal blood flow.Numerous studies have presented in vitro and in viv...
关键词:MAGNESIUM STENT CYTOCOMPATIBILITY in vitro in vivo 
Multifunctional mussel-inspired copolymerized epigallocatechin gallate(EGCG)/arginine coating:the potential as an ad-layer for vascular materials被引量:1
《Regenerative Biomaterials》2016年第4期247-255,共9页Rifang Luo Linlin Tang Lingxia Xie Jin Wang Nan Huang Yunbing Wang 
The author would like to thank Dr Manfred.F.Maitz for his selfless assistance of this job and appreciate Mr Chongxi Jiang and Mrs Ru Shen for their help and contributions on sample characterization and analysis.Specially thank Miss Si Zhong and Mr Xin Wang for their help of cell compatibility evaluation.This work was supported by Natural Science Foundation of China(Grant 51173149,81330031 and 31270020);Sichuan Province Science and Technology Support Program(No.2014SZ0128);the 111 Project.The Program of Introducing Talents of Discipline to Universities(B16033).
Surface properties are considered to be important factors in addressing proper functionalities.In this paper,a multifunctional mussel-inspired coating was prepared via the direct copolymerization of epigallocatechin g...
关键词:Mussel chemistry epigallocatechin gallate(EGCG) vascular devices surface modification MULTIFUNCTION 
多方向锻造Mg-Zn-Mn合金的组织与性能的研究被引量:1
《热加工工艺》2015年第9期41-43,50,共4页龚旭 胡钰昊 周世杰 黄楠 
国家自然科学基金项目(81330031)
对Mg-Zn-Mn三元镁合金进行了多方向锻造,工艺参数分别为250℃-6P(P为道次),250℃-9P,300℃-6P,300℃-9P。通过力学和电化学实验和分析得出:对于合金性能的影响,温度的改变比打击道次的改变要明显得多,低温下多方向锻造晶粒细化更显著,...
关键词:Mg-Zn-Mn合金 打击道次 力学性能 腐蚀性能 
Absorbable magnesium-based stent: physiological factors to consider for in vitro degradation assessments被引量:11
《Regenerative Biomaterials》2015年第1期59-69,共11页JuanWang Christopher E.Smith Jagannathan Sankar Yeoheung Yun Nan Huang 
This study was supported by the National Natural Science Foundation of China(Grant No.81330031);Engineering Research Center for Revolutionizing Metallic Biomaterials(NSF-0812348)from the US National Science Foundation;China Scholarship Council 201207000016;2013 Cultivation Program for the Excellent Doctoral Dissertation of Southwest Jiaotong University.
Absorbable metals have been widely tested in various in vitro settings using cells to evaluate their possible suitability as an implant material.However,there exists a gap between in vivo and in vitro test results for...
关键词:MAGNESIUM absorbable stent in vitro in vivo BIODEGRADATION 
岩藻聚糖改性氧化钛与纤维蛋白原的界面反应研究被引量:1
《功能材料》2014年第14期14021-14025,14030,共6页赵安莎 王昭 陈华东 朱晓华 黄楠 
国家重点基础研究发展计划(973计划)资助项目(2011CB606200);国家自然科学基金重点资助项目(81330031)
针对抗凝血生物材料与血浆关键凝血蛋白质界面作用机制欠缺问题,利用岩藻聚糖改性处理Ti-O薄膜材料,结合先进的原位界面表征技术QCM-D(石英微天平技术)和红外光谱原位研究纤维蛋白原在其表面的吸附行为,确定其分子吸附及二级构象变化机...
关键词:氧化钛 岩藻聚糖 纤维蛋白原构象 界面吸附 血液相容性 
Real-Time Characterization of Fibrinogen Interaction with Modified Titanium Dioxide Film by Quartz Crystal Microbalance with Dissipation
《Chinese Journal of Chemical Physics》2014年第3期355-360,共6页An-sha Zhao Zhao Wang Xiao-hua Zhu Manfred F. Maitz Nan Huang 
ACKNOWLEDGMENTS This work was supported by the National Natural Science Foundation of China (No.9732011CB606200 and No.81330031) and Fundamentat Research Funds for the Central Universities (No.SWJTU11CX054). The authors gratefully acknowledge assistance of Mr. Hai-bei Liu at Qsense company for consulting.
The adsorption of fibrinogen can be used as a quick indicator of surface haemocompatibility because of its prominent role in coagulation and platelet adhesion. In this work the molecular interaction between fibrinogen...
关键词:Quartz crystal microbalance with dissipation Fibrinogen adsorption Confor- mation change Blood platelet 
Current status of research and application in vascular stents被引量:3
《Chinese Science Bulletin》2013年第35期4362-4370,共9页QI PengKai YANG Ying MAITZ F Manfred HUANG Nan 
supported by the National Basic Research Program of China(2011CB606204);the National Natural Science Foundation of China(81330031,81271701)
Cardiovascular diseases have been the leading cause of death in modern society.Using vascular stents to treat these coronary and peripheral artery diseases has been one of the most effective and rapidly adopted medica...
关键词:血管支架 心血管疾病 应用 冠状动脉 内皮祖细胞 干预措施 生物分子 时间序列 
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