国家自然科学基金(30670077)

作品数:4被引量:5H指数:2
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相关作者:宋建华南方曾宪东梁昌镛王倩更多>>
相关机构:中国科学院中国科学院研究生院更多>>
相关期刊:《Science China(Life Sciences)》《Virologica Sinica》更多>>
相关主题:HEARNPVACMNPVFUNCTIONAL_ANALYSISBACULOVIRUSARMIGERA更多>>
相关领域:生物学农业科学医药卫生更多>>
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Functional analysis of the Autographa californica nucleopolyhedrovirus IAP1 and IAP2被引量:3
《Science China(Life Sciences)》2009年第8期761-770,共10页Just M.Vlak 
Supported by the National Basic Research and Development Program of China (Grant No. 2003CB1140);the National Nature Science Foundation of China (Grant Nos. 30325002 and 30670077);in part by a grant from the Royal Netherlands Academy of Arts and Sciences (KNAW) (Program Strategic Scientific Alliances Project,Grant No. 04-PSA-BD-02)
The Autographa californica nucleopolyhedrovirus(AcMNPV) contains three apoptosis suppressor genes:p35,iap1 and iap2.AcMNPV P35 functions as a pancaspase inhibitor,but the function of IAP1 and IAP2 has not been entirel...
关键词:iap1 iap2 ACMNPV HEARNPV 
苜蓿银纹夜蛾核多角体病毒iap1和iap2基因功能分析被引量:1
《中国科学(C辑)》2009年第2期193-201,共9页曾宪东 南方 梁昌镛 宋建华 王倩 JustM.Vlak 陈新文 
国家重点基础研究发展计划(批准号:2003CB1140);国家自然科学基金(批准号:30325002和30670077);和荷兰皇家艺术和科学院(批准号:KNAW,Program Strategic Scientific Alliances project 04-PSA-BD-0)资助项目
苜蓿银纹夜蛾核多角体病毒(Autographa californica nucleopolyhedrovirus,AcMNPV)基因组含有3个细胞凋亡抑制基因,即p35,iap1和iap2.其中,p35作为一个有效的依赖于天冬氨酸的半胱氨酸蛋白酶(caspase)抑制因子,能够抑制多种因素诱发细...
关键词:凋亡抑制基因(iap) ACMNPV HEARNPV 
The ORF 113 of Heliocoverpa armigera Single Nucleopolyhedrovirus Encodes a Functional Fibroblast Growth Factor被引量:2
《Virologica Sinica》2008年第5期321-329,共9页Xiang LI Chang-yong LIANG Jian-hua SONG Xin-wen CHEN 
National Nature Science Foundations of China (30325002,30670077);National Basic Research Priorities Program of China (2003CB1140).
Fibroblast growth factor (FGF) is a key regulator of developmental processes. A FGF homolog (vFGF) is found in all lepidopteran baculoviruses. Autographa californica nucleopolyhedrovirus (AcMNPV) and Bombyx mori NPV (...
关键词:Helicoverpa armigera nucleopolyhedrovirus (HearNPV) Fibroblast growth factor (FGF) BACULOVIRUS Open reading frame 113 (ORF 113) 
Baculovirus-mediated Expression of p35 Confers Resistance to Apoptosis in Human Embryo Kidney 293 cells
《中国病毒学》2007年第5期389-396,共8页Jian-hua SONG Chang-yong LIANG Xin-wen CHEN 
Foundation items:National Nature Science Foundations of China (30325002,30670077);Innovative Foundations Wuhan Institute of Virology,CAS (020208)
Baculovirus has many advantages as vectors for gene transfer.We demonstrated that recombinant baculovirus vectors expressing p35(Ac-CMV-p35) and eGFP(Ac-CMV-GFP) could be transduced into human kidney 293 cells efficie...
关键词:细胞凋亡 基因治疗 P35基因 基因表达 胚胎肾细胞 杆状病毒 
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