supported by grants from the Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (grant No.QYZDJ-SSW-SMC021);the National Natural Science Foundation of China (grants No.31621061 and 31130058);the Virology Key Frontier Science Program of State Key Laboratory of Virology (grant No.klv-2016-03);the National Key R&D Program of China (2017YFD0200400);sponsored by CAS-TWAS President’s Fellowship for International PhD Students
Effective oral infection is set off by interaction of a group of conserved per os infectivity factors(PIFs) with larval midgut columnar epithelial cells. We constructed pseudotyped viruses by substituting pif1, pif2 o...
A recombinant Helicoverpa armigera nucleopolyhedrovirus (HearNPV) ex- pressing the insect-selective neurotoxin (RjAalTjO from Cuban scorpion Rhopalurus junceus was constructed by replacing the UDP-glucosyltransfera...
supported by the grants from the National Science Foundation of China (No. 31370191 and 31621061);the Strategic Priority Research Program of the Chinese Academy of Sciences (grant XDB11030400);Open Research Fund Program of the Key Laboratory of Agricultural and Environmental Microbiology, Chinese Academy of Sciences
The envelope fusion protein F of baculoviruses is a class I viral fusion protein which play a significant role during virus entry into insect cells. F is initially synthesized as a precursor(F_0) and then cleaved in...
supported by grants from the National Science Foundation of China (No.31200124 and 31321001);the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No.XDB11030400)
Fibroblast growth factor(FGF) is found throughout multicellular organisms; however, fgf homologs(vfgf) have only been identified among viruses in lepidopteran baculoviruses. The function of v FGFs from Group I alphaba...
supported by the National Science Foundation of China(31130058 to Z.H.).Monoclonal Antibodies against HearNPV P74
P74 is a per os infectivity factor of baculovirus.Here,we report the production of three monoclonal antibodies (mAbs),denoted as 20D9,20F9 and 21E1,raised against P74 of Helicoverpa armigera nucleopolyhedrovirus (Hear...
National Nature Science Foundations of China (31030027,30770085 and 30800044)
Protein phosphorylation is one of the most common post-translational modification processes that play an essential role in regulating protein functionality.The Helicoverpa armigera single nucleopolyhedrovirus (HearNPV...
Supported by the National Basic Research and Development Program of China (Grant No. 2003CB1140);the National Nature Science Foundation of China (Grant Nos. 30325002 and 30670077);in part by a grant from the Royal Netherlands Academy of Arts and Sciences (KNAW) (Program Strategic Scientific Alliances Project,Grant No. 04-PSA-BD-02)
The Autographa californica nucleopolyhedrovirus(AcMNPV) contains three apoptosis suppressor genes:p35,iap1 and iap2.AcMNPV P35 functions as a pancaspase inhibitor,but the function of IAP1 and IAP2 has not been entirel...