Supported by the National Natural Science Foundation of China (No. 30200369)
Objective: To improve DC-based tumor vaccination, we studied whether dendritic ceils (DCs) which cocultured with H22 liver cancer cells-derived heat shock protein (HSP) glycoprotein 96 (gp96) affect the T cell-...
National Natural Science Foundation of China (No.30200369)
Objective: Heat shock protein (HSP) has the promiscuous abilities to chaperone and present a broad repertoire of tumor antigens to antigen presenting cells including DCs. In this report, we analyzed the modulation ...
Supported by National Natural Science Foundation of Chi-na (NO.30200369)
Objective: To investigate the antitumor effect of dendritic cell (DC) modified by gp96-peptide complexes both in vitro and in vivo. Methods:Gp96-peptide complexes were acquired from H22 liver cancer cells in mice....