国家自然科学基金(31071284)

作品数:3被引量:2H指数:1
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相关作者:宋砚泽苏立波林鑫华李雪吴一卉更多>>
相关机构:中国科学院大学温州医科大学中国科学院更多>>
相关期刊:《中国科学:生命科学》《Journal of Genetics and Genomics》更多>>
相关主题:NOTCHDROSOPHILA蛋白家族复合物发育更多>>
相关领域:生物学医药卫生更多>>
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囊泡转运复合物Retromer和SNX蛋白家族在发育和疾病中的作用被引量:2
《中国科学:生命科学》2016年第1期36-51,共16页宋砚泽 沈成豪 李雪 苏立波 林鑫华 吴一卉 
国家重点基础研究发展计划(批准号:2011CB943901;2011CB943902);国家自然科学基金(批准号:31071284;31371464)资助
逆向囊泡转运复合物Retromer主要负责介导货物蛋白从内体向反式高尔基体或细胞表面逆向转运,是细胞内囊泡转运分选系统的重要成员.Retromer复合物主要含有两个亚复合体:货物选择复合体VPS26-VPS29-VPS35和膜结合复合体SNX-BAR.本文着重...
关键词:RETROMER 囊泡转运复合物 SNX蛋白家族 发育 退行性疾病 
Drosophila heparan sulfate 3-0 sulfotransferase B Null Mutant Is Viable and Exhibits No Defects in Notch Signaling
《Journal of Genetics and Genomics》2014年第7期369-378,共10页Yueqin Guo Ying Feng Zhouhua Li Xinhua Lin 
supported by the grants from the National Basic Research Program of China(Nos.2011CB943901,2011CB943902 and 2011CB943802);the National Natural Science Foundation of China(Nos.31030049,31271582 and 31071284);Strategic Priority Research Program of the Chinese Academy of Sciences Grant(No.XDA01010101)
Heparan sulfate proteoglycans (HSPGs) are critically involved in a variety of biological events. The functions of HSPGs are determined by the nature of the core proteins and modifications of heparan sulfate (HS) g...
关键词:DROSOPHILA heparan sulfate proteoglycans Hs3st-A Hs3st-B NOTCH 
dBrms1 Acts as a Positive Regulator of Notch Signaling in Drosophila Wing
《Journal of Genetics and Genomics》2014年第6期317-325,共9页Qinghai Zhang Yan Zhang Longfei Wu Yongfei Yang Xue Li Lei Gao Xiaomeng Hou Yihui Wu Guoli Hou Zhouhua Li Xinhua Lin 
supported by the grants from National Basic Research Program of China (Nos.2011CB943901, 2011CB943902 and 2011CB943802);the National Natural Science Foundation of China (Nos.31030049, 31271582 and 31071284);the Strategic Priority Research Program of the Chinese Academy of Sciences(No. XDA01010101)
The highly conserved Notch signaling is precisely regulated at different steps in a series of developmental events. However, little is known about the regulation of Notch receptor at transcriptional level. Here, we de...
关键词:Notch signaling DROSOPHILA Wing disc Notch transcription dBrmsl 
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