This work was supported by the following funds: National Natural Science Foundation of China (No.30670951); Guangdong Provincial; Natural Science Foundation (No.06021322); Fund of Guangzhou Municipal; Scientific Problem-Solving Program (No. 2003 Z 3-E0381); Fund of Guangdong; Provincial Scientific Problem-Solving Program (No.2005 B31211002); Guangdong Provincial Government and Ministry of Education Project com- bining project initiation, study and research (No.2009B090300277).
OBJECTIVE To investigate the effect of polyethylene imine glycol (PEI-PEG)/siRNA nanocomposites in the in vitro transfection of human gastric cancer SGC7901 cell lines and the down-regulation of gene expression of t...