supported by the National Natural Science Foundation of China (21203166, 21073164);Natural Science Foundation of Zhejiang Province, China (Y4100620, LY12B04003);Student Innovation Foundation of Zhejiang Province, China (2012R408007)~~
supported by the National Natural Science Foundation of China (21073164,20673098);the Natural Science Foundation of Zhejiang Province (Y4100620);the Research Foundation of the Education Bureau of Zhejiang Province (Y200906517)
The mechanism of the action of copper-dependent quercetin 2,3-dioxygenase (2,3QD) has been investigated by means of hy- brid density functional theory. The 2,3QD enzyme cleaves the O-heterocycle of a quercetin by in...