国家自然科学基金(30572176)

作品数:13被引量:8H指数:2
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相关作者:方琦陈忠诸葛正兵金春雷更多>>
相关机构:浙江大学医学院附属邵逸夫医院浙江大学更多>>
相关期刊:《中国药理通讯》《浙江大学学报(医学版)》《Acta Pharmacologica Sinica》更多>>
相关主题:CARNOSINEINHIBITS肌肽STIMULATIONRATS更多>>
相关领域:医药卫生更多>>
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杏仁核电点燃癫痫对大鼠穿梭箱被动回避反应的记忆保持能力的作用被引量:5
《浙江大学学报(医学版)》2008年第5期463-467,共5页诸葛正兵 方琦 金春雷 陈忠 
国家自然科学基金(No.30572176);浙江省自然科学基金重点项目(No.Z207289)
目的:探讨杏仁核电点燃癫痫对大鼠穿梭箱被动回避反应的记忆保持能力的影响。方法:大鼠每24h进行一次电刺激直至完全点燃,然后利用穿梭箱系统检测慢性电点燃癫痫对大鼠被动回避反应的记忆保持能力的作用;另一组动物于训练前5min给予杏...
关键词:癫痫 杏仁核 疾病模型 动物 点燃效应(神经病学) 电刺激 慢性病 记忆障碍/病因学 
Endogenous histamine inhibits the development of morphine-induced conditioned place preference被引量:2
《Acta Pharmacologica Sinica》2007年第1期10-18,共9页Ying-xia GONG Min LV Yong-ping ZHU Yuan-yuan ZHU Er-qing WEI Hong SHI Qun-li ZENG Zhong CHEN 
a National Rasic Research of China grant (No_ 2003CB515400);National Natural Science Foundation of China grants(No_ 30371638, 30472013 and 30572176);the Zhejiang Provincial Natural Science Foundation of China (No 8303779)
Aim: The conditioned place preference (CPP) paradigm was used to investigate the effects of endogenous histamine on the processes leading to morphineinduced reward-seeking behavior in Sprague-Dawley rats. Methods:...
关键词:conditioned place preference HISTAMINE MORPHINE RAT tuberomammillary nucleus 
Histamine H3 receptor antagonist clobenpropit enhaces GABA release to protect against NMDA -induced excitotoxicity in cultured cortical neurons through the cAMP/PKA pathway
《中国药理通讯》2006年第4期22-22,共1页Dai Hai-Bin Fu Qiu-Li Shen Yao Chen Zhong 
This project was supported by grants from the National Natural Science Foundation of China (30572176 and 30600757) and the Zhejiang Provincial Natural Science Foundation of China (R303779)
关键词:组胺H3受体拮抗剂 CLOBENPROPIT GABA释放 NMDA诱发兴奋毒性 皮质神经元 cAMP/PKA通道 
Protective effect of carnosine against NMDA -induced neurotoxicity in differentiated rat PC12 cells被引量:1
《中国药理通讯》2006年第4期23-23,共1页Shen Yao Fan Yan -Yin Fan Xiao -Ning Dai Hai- Bin Fu Qiu-Li Hu Wei-Wei Hu ChenZhong 
This project was supported by grants from the National Natural Science Foundation of China ( 30572176 and 30600757 ) and the Zhejiang Provincial Natural Science Foundation of China (R303779)
关键词:肌肽 NMDA诱发神经毒性 神经保护作用 大鼠模型 分化PC12细胞 
Protective effect of carnosine on amyloid - β42 - induced neurotoxicity in differentiated rat PC12 cells is independent of histamine pathway
《中国药理通讯》2006年第4期33-33,共1页Fu Qiu-Li Dai Hai-Bin Shen Yao Hu Wei-wei Chen Zhong 
This project was supported by grants from the National Natural Science Foundation of China (30572176 and 30600757 ) and the Zhejiang Provincial Natural Science Foundation of China (R303779)
关键词:肌肽 β淀粉样多肽- β42 诱发神经毒性 大鼠PC12分化细胞 保护作用 组胺通路 
Unilateral low -frequency stimulation of central piriform cortex has inhibitory effect on amygdaloid- kindled seizures in rats
《中国药理通讯》2006年第4期54-55,共2页Zhu - Ge Zheng - Bing Zhu Yuan - Yuan Wu Deng - Chang Wang Shuang Chen Zhong 
This Project was supported by grants from the National Natural Science Foundation of China (30371638, 30572176, 30600194), and the Zhejiang Provincial Natural Science Foundation of China (R303779)
关键词:大鼠 梨状皮质 单侧低频刺激 杏仁核点燃癫痫 四肢抽搐 抑制作用 
Low frequency stimulation of fastigial nucleus delays amygdaloid kindling seizures in rats
《中国药理通讯》2006年第4期55-55,共1页Wang Shuang Wu Deng - Chang Zhu - Ge Zheng - Bing Zhu Yuan- Yuan Chen Zhong 
This Project was supported by grants from the National Natural Science Foundation of China (30600194, 30371638, 30572176)
关键词:大鼠 顶核 低频刺激 杏仁核点燃癫痫 耐药性癫痫 
ω- Conotoxin MVIIA inhibits amygdaloid kindled seizures in rats
《中国药理通讯》2006年第4期55-56,共2页Wu Deng-Chang Wang Shuang Zhu Yuan-Yuan Chen Zhong 
This Project was supported by grants from the National Natural Science Foundation of China (30371638, 30572176, 30600194)
关键词:大鼠 杏仁核点燃癫痫 ω -芋螺毒素MVIIA 抑制作用 
Lesion of the TM E2 -region attenuates postictal seizure protection in rats
《中国药理通讯》2006年第4期56-56,共1页Wu Deng - Chang Zhu - Ge Zheng - Bing Wang Shuang Zhu Yuan - Yuan Jin Chun -Lei Chen Zhong 
This Project was supported by grants from the National Natural Science Foundation of China (30371638, 30572176, 30600194) , and the Zhejiang Provincial Natural Science Foundation of China (R303779)
关键词:大鼠 癫痫发作后保护 下丘脑 结节乳头核E2区 电解损毁 
Low - frequency stimulation of histaminergic tuberomammillary nucleus facilitates basolateral amygdaloid kindling in rats
《中国药理通讯》2006年第4期56-57,共2页Zhu- Ge Zheng-Bing Wu Deng- Chang Wang Shuang Jin Chun- Lei Chen Zhong 
  This Project was supported by grants from the National Natural Science Foundation of China (30371638, 30572176, 30600194), and the Zhejiang Provincial Natural Science Foundation of China ( R303779 )  
关键词:大鼠 基底外侧杏仁核点燃 癫痫 低频刺激 下丘脑结节乳头核 组胺能神经元 
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