supported by the National Basic Research Program of China(2009CB918602);the National Natural Science Foundation of China(30970575 and 31011120381);Shanghai Leading Academic Discipline Project(B111);Qi Qiwas supported by the National Talent Training Fund in Basic Research of China(J1210012)
The membrane fusion protein CmeA and the outer membrane channel CmeC,two important components of CmeABC system in Campylobacter jejuni,were expressed in Escherichia coli.After Ni-NTA and ion exchange columns purificat...
supported by the National Basic Research Program of China (973 Project, Grant No. 2007CB814800 and2013CB834100);the Shanghai Leading Academic Discipline Project (Grant No. B111);the National Key Laboratory of Applied Surface Physics and the Department of Physics, Fu-dan University
Shigella species and Escherichia coli are closely related organisms. Early phenotyping experiments and several recent molecular studies put Shigella within the species E. coli. However, the whole-genome-based, alignme...
supported by the National Natural Science Foundation of China (Grant Nos.10825520 and 11175230);the Shanghai Leading Academic Discipline Project (B111);the Knowledge Innovation Program of the Chinese Academy of Sciences;the Shanghai Supercomputer Center of China
Based on a simple model, we theoretically show that asymmetric transportation is possible in nanoscale systems experiencing thermal noise without the presence of extemal fluctuations. The key to this theoretical advan...
This study was supported in part by grants from the National Natural Sci-ence Foundation of China(Grant No.30570406);the HI-tech Re-search and Development Program of China(Grant No.2008AA02Z311);the Shanghai Leading Academic Discipline Project(B111).
Protein folding,stability,and function are usually in-fluenced by pH.And free energy plays a fundamental role in analysis of such pH-dependent properties.Elec-trostatics-based theoretical framework using dielectric so...
by the Shanghai Leading Academic Discipline Project(B111);NSFC(Grant No.30800322);Shanghai Pujiang Program(08PJ1401300);Ministry of Education Start Fund to Returned Overseas Scholars;Ministry of Education Research Fund for New Teachers in Doctoral Program of Higher Educational Institutes;National Basic Research Program of China(973 Program)(Grant No.2011CB503703);and Institute of Brain Sciences at Fudan University.The funders had no role in study design,data collection and analysis,decision to publish,or preparation of the manuscript.
The sigma-1 receptor is a molecular chaperone protein highly enriched in the brain.Recent studies linked it to many diseases,such as drug addition,Alzheimer’s disease,stroke,depression,and even cancer.Sigma-1 recepto...