《Chinese Journal of Cancer Research》

作品数：2515被引量：10150H指数：35
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《Chinese Journal of Cancer Research》
主办单位：China Anti-Cancer Association
最新期次：2025年1期更多>>
发文主题：GASTRIC_CANCERBREAST_CANCERPROGNOSISEXPRESSIONPATIENTS更多>>
发文领域：医药卫生生物学农业科学文化科学更多>>
发文作者：ChineseSocietyofClinicalOncologyCSCOdiagnosisandtreatmentguidelinesforpersistentrecurrentandmetastaticdifferentiatedthyroidcancerworkinggroup更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>
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Improving neuroblastoma risk prediction through a polygenic risk score derived from genome-wide association study-identified loci
《Chinese Journal of Cancer Research》2025年第1期1-11,共11页Wenli Zhang Jinhong Zhu Mengzhen Zhang Jiaming Chang Jiabin Liu Liping Chen Xinxin Zhang Haiyan Wu Chunlei Zhou Jing He 
supported by grants from the National Natural Science Foundation of China(No.82173593,32300473);Guangzhou Science and Technology Project(No.2025A04J4537,2025A04J4696);Guangdong Basic and Applied Basic Research Foundation(No.2023A1515220053);Postdoctoral Science Foundation of Jiangsu Province(No.2021K524C).
Objective:Neuroblastoma is the most common extracranial solid tumor in children and has complex genetic underpinnings.Previous genome-wide association studies(GWASs)have identified many loci associated with neuroblast...
关键词：GWAS POLYMORPHISM NEUROBLASTOMA SUSCEPTIBILITY polygenic risk score 
CT-based radiomics-deep learning model predicts occult lymph node metastasis in early-stage lung adenocarcinoma patients:A multicenter study
《Chinese Journal of Cancer Research》2025年第1期12-27,共16页Xiaoyan Yin Yao Lu Yongbin Cui Zichun Zhou Junxu Wen Zhaoqin Huang Yuanyuan Yan Jinming Yu Xiangjiao Meng 
supported by the National Natural Science Foundation of China(No.82272845);the Natural Science Foundation of Shandong(No.ZR2023ZD26).
Objective:The neglect of occult lymph nodes metastasis(OLNM)is one of the pivotal causes of early non-small cell lung cancer(NSCLC)recurrence after local treatments such as stereotactic body radiotherapy(SBRT)or surge...
关键词：Radiomics lung adenocarcinoma occult lymph node metastasis deep learning 
Deep learning-based multi-task prediction of response to neoadjuvant chemotherapy using multiscale whole slide images in breast cancer:A multicenter study
《Chinese Journal of Cancer Research》2025年第1期28-47,共20页Qin Wang Feng Zhao Haicheng Zhang Tongpeng Chu Qi Wang Xipeng Pan Yuqian Chen Heng Zhou Tiantian Zheng Ziyin Li Fan Lin Haizhu Xie Heng Ma Lan Liu Lina Zhang Qin Li Weiwei Wang Yi Dai Ruijun Tang Jigang Wang Ping Yang Ning Mao 
supported by the National Natural Science Foundation of China(No.82371933);the National Natural Science Foundation of Shandong Province of China(No.ZR2021MH120);the Taishan Scholars Project(No.tsqn202211378);the Shandong Provincial Natural Science Foundation for Excellent Young Scholars(No.ZR2024YQ075).
Objective:Early predicting response before neoadjuvant chemotherapy(NAC)is crucial for personalized treatment plans for locally advanced breast cancer patients.We aim to develop a multi-task model using multiscale who...
关键词：Artificial intelligence breast cancer digital pathology whole slide images 
Clinicopathological and molecular features of HR^(+)/HER2^(−)breast cancer patients with distinct endocrine resistance patterns
《Chinese Journal of Cancer Research》2025年第1期48-65,共18页Siwei Zhang Han Wang Hang Zhang Qingyuan Zhuang Xiaohui Zhu Yi Xiao Yizhou Jiang 
supported by the National Key Research and Development Program of China(No.2020YFA0112304);the National Natural Science Foundation of China(No.82373167,82341003 and 92159301);the Natural Science Foundation of Shanghai(No.22ZR1479200);the Shanghai Key Laboratory of Breast Cancer(No.12DZ2260100);the SHDC Municipal Project for Developing Emerging and Frontier Technology in Shanghai Hospitals(No.SHDC12021103);Shanghai Medical Innovation Research Project(No.22Y11912700),and Shanghai Anticancer Association EYAS PROJECT(No.SACA-CY22A05).
Objective:Recurrence continues to be a pivotal challenge among hormone receptor-positive(HR^(+))/human epidermal growth factor receptor 2^(−)negative(HER2^(−))breast cancers.In the international consensus guidelines,H...
关键词：HR^(+)/HER2^(−)breast cancer endocrine resistance cancer recurrence multiomics analysis precise treatment 
Prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer after curative surgery:Final results of a phase Ⅱ trial
《Chinese Journal of Cancer Research》2025年第1期66-72,共7页Biao Fan Hao Su Lingqian Wang Xin Ji Yinan Zhang Ziyu Jia Ji Zhang Zhaode Bu Xiaojiang Wu 
supported by the National Nature Science Foundation of China(No.81402308);Science Foundation of Peking University Cancer Hospital(No.2021-24);Natural Science Foundation of Beijing Municipal(No.7242020);Science Foundation of Peking University Cancer Hospital(No.BJCH2025GG04);the National Nature Science Foundation of China(No.82173151).
Objective:The trial was designed to evaluate the efficacy of prophylactic hyperthermic intraperitoneal chemotherapy(HIPEC)with cisplatin for patients with locally advanced gastric cancer(LAGC).Methods:Between March 20...
关键词：Gastric cancer intraperitoneal chemotherapy CISPLATIN PROGNOSIS 
Composite score of PD-1^(+)CD8^(+)tumor-infiltrating lymphocytes and CD57^(+)CD8^(+)tumor ascites lymphocytes is associated with prognosis and tumor immune microenvironment of patients with advanced high-grade serous ovarian cancer
《Chinese Journal of Cancer Research》2025年第1期73-89,共17页Tianhui He Jie Zhang Lin Zeng Zhongnan Yin Bo Yu Xi Zhang Xiaoxue Yang Chunliang Shang Lixiang Xue Hongyan Guo 
supported by National Natural Science Foundation of China(No.82372888);National Key Research and Development Program of China(No.2022YFC2704000);National Natural Science Foundation of China(No.82273383);the Capital’s Funds for Health Improvement and Research(No.2020-2-4098);Youth program of Beijing Municipal Natural Science Foundation(No.7204328);Clinical Medicine Plus X-Young Scholars Project,Peking University(No.PKU2022LCXQ020);Key Clinical Project of Peking University Third Hospital(No.BYSY2022050);Key Clinical Projects of Peking University Third Hospital(No.BYSYZD2021006);Key Clinical Projects of Peking University Third Hospital(No.BYSYZD2019034).
Objective:The expression of programmed death 1(PD-1)on CD8^(+)T cells is associated with their activation and exhaustion,while CD57 serves as a senescence marker.The impact of PD-1^(+)and CD57^(+)CD8^(+)T cells on the...
关键词：High-grade serous ovarian cancer PD-1^(+)CD8^(+)T cells CD57^(+)CD8^(+)T cells PROGNOSIS biomarker 
Integrated analysis of single-cell and bulk transcriptomes uncovers clinically relevant molecular subtypes in human prostate cancer
《Chinese Journal of Cancer Research》2025年第1期90-114,共25页Tao Ding Lina He Guowen Lin Lei Xu Yanjun Zhu Xinan Wang Xuefei Liu Jianming Guo Fanghong Lei Zhixiang Zuo Jianghua Zheng 
supported by Shanghai Science and Technology Commission,China(No.21S11902100);Shanghai Municipal Health Commission Scientific Research Project(No.202140308);Clinical Research Project of Tongji Hospital of Tongji University[No.ITJ(ZD)2209];Shanghai Tongji Hospital National Natural Science Foundation Cultivation Project(No.GJPY2216);Shanghai Medical Innovation Research Special Foundation(No.23Y11908800);CSCO-Haosen Oncology Research Fund(No.Y-HS202301-0096).
Objective:Prostate cancer(PCa)is a complex disease characterized by diverse cellular ecosystems within the tumor microenvironment(TME)and high tumor heterogeneity,which challenges clinically stratified management and ...
关键词：Single-cell RNA sequencing prostate cancer lineage plasticity tumor heterogeneity molecular classification 
Adaptive neoadjuvant endocrine therapy screens out prime population of ribociclib intensive adjuvant therapy
《Chinese Journal of Cancer Research》2025年第1期115-117,共3页Zhao Bi Tongyue Ren Yongsheng Wang 
supported by China Postdoctoral Science Foundation(No.2022M721987);Natural Science Foundation of Shandong Province(No.ZR2024QH058).
The latest data from the NATALEE trial showed the absolute 3-year invasive disease-free survival benefit was 4.9%between the experimental and control groups.That is to say,in the intermediate-risk hormone receptor pos...
关键词：Breast cancer Ribociclib hormone receptor positive/human epidermal growth factor receptor-2 negative subgroup neoadjuvant endocrine therapy 
Corrigendum to National validation of laparoscopic approach for locally advanced gastric cancer:Comparison of a randomized controlled trial and real-world practice results
《Chinese Journal of Cancer Research》2025年第1期118-118,共1页
In this article,the department of the author Joo-Ho Lee“Department of Surgery,Ewha Womans University Mokdong Hospital,Seoul 07985,Republic of Korea”was incorrectly listed.It has been updated as follows:Joo-Ho Lee.De...
关键词：real world practice locally advanced gastric cancer laparoscopic approach randomized controlled trial 
《整合肿瘤学》征订通知
《Chinese Journal of Cancer Research》2025年第1期F0003-F0003,共1页
各专委会、省市自治区抗癌协会、医疗机构、科研院所、团体会员单位、各位专家:为了推动肿瘤整合医学的发展,中国抗癌协会理事长樊代明院士领衔,郝希山院士、詹启敏院士、于金明院士、王红阳院士、赫捷院士,张岂凡、季加孚、李强、郭小...
关键词：中国抗癌协会 张岂凡 季加孚 詹启敏 赫捷 
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