supported by the National Natural Science Foundation of China(82130112);Capital’s Funds for Health Improvement and Research(CFH2024-2-1193);the Youth Beijing Scholar(2022-051).
Background:Type 2 diabetes(T2D)has already become a global pandemic.As its simple,rapid,economical,and relatively non-invasive,metabolic markers have become a method for T2D diagnosis.However,region,race,and diet all ...
supported by grants from the Tianjin Health Technology Project(Grant no.2022QN106).
Background:The Fascin(FSCN)family,comprising actin-bundling proteins,plays vital roles in cytoskeletal reorganization and cell migration.FSCN1,FSCN2,and FSCN3 are implicated in cancer progression through cell motility...
Background:Colon adenocarcinoma(COAD)is a gastrointestinal malignancy with a high mortality rate.Studies have confirmed the role of immunogenic cell death(ICD)in different cancer types.However,there is a lack of resea...
Background:Meta-analysis is a quantitative approach that systematically integrates results from previous research to draw conclusions.Structural equation modelling is a statistical method that integrates factor analys...
the Education Department of Hebei Province(Project No.QN2016145)and the University Student Research Project of Chengde Medical University(2024038)for the funding support.
Background:The specific role of statins in the field of ophthalmology is not clear.Statins have the advantages of pleiotropic,relatively safety and low cost,and are a promising choice for the prevention and management...
supported by grants from the Tianjin Health Technology Project(Grant no.2022QN106).
Background:The ORAI family of proteins,comprising ORAI1,ORAI2,and ORAI3,plays a crucial role in the regulation of intracellular calcium signaling,which is essential for various cellular functions including proliferati...
supported by Chongqing Natural Science Foundation General Project(cstc2021jcyi msxmX0069);Chongqing Social Science Planning Project(2022NDYB196).
Background:The prevalence of multimorbidity is increasing,with a notable shift towards younger age groups.Methods:Convenience sampling was employed to select 15,988 young and middle-aged adults in Chongqing as the stu...
The gastrointestinal system of the human body is home for a large number and rich variety of microbes,including bacteria,viruses,fungi and protozoa,which are collectively known as the gut microbiota(the largest and mo...
supported by the Joint Special Fund for Applied Basic Research of Yunnan Provincial Science and Technology Department and Kunming Medical University(202101AY070001-217).
Background:Kawasaki disease is an acute immune vasculitis,which is more common in children under 5 years old.Kawasaki disease mainly affects the cardiovascular system,especially the coronary arteries.Once coronary art...
Background:Stroke is one of the most dangerous and life-threatening disease as it can cause lasting brain damage,long-term disability,or even death.The early detection of warning signs of a stroke can help save the li...