ASTRAGALUS

作品数:190被引量:672H指数:13
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相关领域:医药卫生农业科学更多>>
相关作者:曹卫东王学红梁剑平杨贤鹏郝宝成更多>>
相关机构:中国农业大学东北师范大学中国科学院华中农业大学更多>>
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相关基金:国家自然科学基金公益性行业(农业)科研专项国家高技术研究发展计划国家教育部博士点基金更多>>
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Deciphering the mechanism of action of Chaihu-Astragalus compound in the management of alcoholic liver fibrosis:A network pharmacology and molecular docking approach
《Journal of Chinese Pharmaceutical Sciences》2025年第2期163-174,共12页Xiaodong Zhu Xueshi Di Jinhui Sun 
National Natural Science Foundation of China(Grant No.81573969).
The present study aimed to analyze the potential mechanism of action of Chaihu-Astragalus in treating alcoholic liver fibrosis using network pharmacology and molecular docking techniques.We initially screened the acti...
关键词:Alcoholic liver fibrosis Chaihu-Astragalus Network pharmacology Molecular docking 
Phylogenetic diversity and regionalization in the temperate arid zone
《Journal of Systematics and Evolution》2024年第6期1201-1217,共17页Ryan A.Folk Aliasghar A.Maassoumi Carolina M.Siniscalchi Heather R.Kates Douglas E.Soltis Pamela S.Soltis Michael B.Belitz Robert P.Guralnick 
supported by the National Science Foundation(USA),grant number DEB-1916632;the Department ofEnergy(DOE),grant number DE-SC0018247.
Astragalus (Fabaceae) is astoundingly diverse in temperate, cold arid regions of Earth, positioning this group as a model clade for investigating the distribution of plant diversity in the face of environmental challe...
关键词:ASTRAGALUS BIOGEOGRAPHY CANAPE Iran phyloregion spatial phylogenetics 
Network pharmacology and molecular dynamics study of the effect of the Astragalus-Coptis drug pair on diabetic kidney disease
《World Journal of Diabetes》2024年第7期1562-1588,共27页Mo-Yan Zhang Shu-Qin Zheng 
BACKGROUND Diabetic kidney disease(DKD)is the primary cause of end-stage renal disease.The Astragalus-Coptis drug pair is frequently employed in the management of DKD.However,the precise molecular mechanism underlying...
关键词:Astragalus membranaceus Coptis chinensis Franch Diabetic kidney disease Network pharmacology Molecular docking Molecular dynamics simulation 
Exploring the mechanism of Astragalus and Salvia miltiorrhiza in the treatment of chronic glomerulonephritis:A network pharmacology approach被引量:1
《Journal of Chinese Pharmaceutical Sciences》2024年第7期620-630,共11页Nianjing Qi Mingxun Yang Shan Mao 
Specialized Research on Traditional Chinese Medicine in Henan Province(Grant No.KJGG108).
To elucidate the mechanism underlying the therapeutic impact of Astragalus-Danshen in chronic glomerulonephritis(CGN),a comprehensive exploration was conducted utilizing network pharmacology.The TCMSP database was emp...
关键词:ASTRAGALUS SALVIA Chronic nephritis Drug pairs Signaling pathway 
Mechanism prediction of Astragalus mongholicus Bunge and Angelica sinensis Diels in treating interstitial lung disease based on network pharmacology and molecular docking
《TMR Pharmacology Research》2023年第4期1-9,共9页Jun Du Jian Hao Wei Wei 
Funded by National Natural Science Foundation of China(81903934);Tianjin Health Science and Technology Project(ZC20205).
Objective:To investigate the mechanism by which Astragalus mongholicus Bunge(AM),and Angelica sinensis Diels(AS)act in interstitial lung disease(ILD)based on computational prediction.Methods:We screened the ingredient...
关键词:Astragalus mongholicus Bunge Angelica sinensis Diels computational prediction interstitial lung disease PI3K-Akt signaling pathways 
Effect of Astragalus-hawthorn on ovarian reproductive function and inflammatory mechanism of action in rats with polycystic ovary syndrome
《Journal of Hainan Medical University》2023年第17期28-33,共6页TIAN Xiu-xiu LI Mei-lin GONG Yu-hang MA Xi-ya ZHANG Xue-juan 
Key R&D Plan Project for Social Development of Shanxi Provincial Department of Science and Technology(No.201903D321224)。
Objective:To investigate the effects of prophylactic administration of Astragalus-Hawthorn on ovarian reproductive function and inflammatory mechanism in rats with polycystic ovary syndrome(PCOS).Methods:Fifty 21-day-...
关键词:Polycystic ovary syndrome Astragalus-Hawthorn Reproductive function Pro-inflammatory factor Anti-inflammatory factor 
Astragalus adscendens extract shows antidiabetic effects through controlling oxidative stress,inflammation and apoptosis in streptozotocin-induced diabetic rats被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2023年第6期242-249,共8页Yosra Raziani Kimia Karami Hamid Reza Mohammadi Hossein Mahmoudvand Mohammad Nabi Moradi Javad Ghasemian Yadegari 
Objective:To assess the effect of oral treatment of methanolic extract of the aerial parts of Astragalus adscendens in streptozotocin-induced diabetic rats.Methods:In order to induce diabetes,rats intraperitoneally re...
关键词:Herbal medicines Astragalus adscendens Diabetes ANTIOXIDANT Antidiabetes STREPTOZOTOCIN ANTIINFLAMMATION 
Characterization of Turkish Astragalus honeys according to their phenolic profiles and biological activities with a chemometric approach
《Food Bioscience》2023年第3期604-614,共11页Selçuk Küçükaydın Gülsen Tel-Çayan Fatih Çayan Meltem Tas-Küçükaydın Büsra Eroglu Mehmet Emin Duru Mehmet Öztürk 
supported by grants from Ministry of Agriculture and Forestry,Turkey and General Directorate of Agricultural Research and Policies(TAGEM 17/AR-GE/13).
The genus of Astragalus provides a significant source of pollen and nectar for honeybees.In this study,37 Astragalus honey samples in 8 different regions from Turkey were investigated for the phenolic compositions and...
关键词:Astragalus honey Phenolic composition Antioxidant activity Antimicrobial activity Enzyme inhibitory activity Chemometric approaches 
A reference-grade genome assembly for Astragalus mongholicus and insights into the biosynthesis and high accumulation of triterpenoids and flavonoids in its roots
《Plant Communications》2023年第2期193-213,共21页Yi Chen Ting Fang He Su Sifei Duan Ruirui Ma Ping Wang Lin Wu Wenbin Sun Qichen Hu Meixia Zhao Lianjun Sun Xuehui Dong 
supported by grants from the City-University Cooperation Project of China(201904710111639).
Astragalus membranaceus var.mongholicus(AMM),a member of the Leguminosae,is one of the most important medicinal plants worldwide.The dried roots of AMM have a wide range of pharmacological effects and are a traditiona...
关键词:Astragalus membranaceus var.mongholicus genome sequences LTR-RTs TRITERPENOID flavonoid 
The research group of Prof.Min Ye and Prof.Xue Qiao made a series of progress in the biosynthesis of astragalus saponins被引量:1
《Journal of Chinese Pharmaceutical Sciences》2022年第12期963-966,共4页 
黄芪皂苷是一类结构特异、活性明确的中药来源天然产物。2022年,北京大学药学院天然药物及仿生药物国家重点实验室叶敏/乔雪团队在黄芪皂苷生物合成研究中取得了系列进展,部分成果发表在AngewandteChemieInternational Edition (IF=16.8...
关键词:黄芪皂苷 中药来源 北京大学药学院 生物合成 天然产物 团队 
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