A catalytic two-component three-centered(2C3C)Ugi-type reaction was developed for the synthesis of L-1-deoxynojirimycin(DNJ)isomers using a chiron approach.This new and quite mild catalytic system,comprised of phenylp...
Financial support from National Basic Research Program of China(No.2012CB822101);the National Natural Science Foundation of China(No.21272240);National Science and Technology Major Projects for "Major New Drugs Innovation and Development"(No.2013ZX09508104);National Engineering Research Center for Carbohydrate Synthesis of Jiangxi Normal University
A novel C-branched polyhydroxylated cyclic nitrone 25.which could be a valuable intermediate for the synthesis of C-branched pyrrolidine iminosugars,was synthesized starting from the commercially available i.-arabinos...
Project support by the National Natural Science Foundation of China (No. 20272054).
Imino sugars, sometimes called azasugars, are an important class of natural and unnatural compounds that have activity to selectively inhibit glycohydrolases responsible for the cleavage of glycosidic bonds.[1,2] ...