SHANK

作品数:27被引量:37H指数:3
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相关领域:医药卫生更多>>
相关作者:张磊刘伟费舟盛树力田金洲更多>>
相关机构:第四军医大学西京医院北京中医药大学首都医科大学宣武医院安徽应流航源动力科技有限公司更多>>
相关期刊:《Chinese Journal of Traumatology》《Science China(Life Sciences)》《中学生英语(中旬刊)》《大众软件》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金福建省自然科学基金更多>>
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Matrine promotes colorectal cancer apoptosis by downregulating shank-associated RH domain interactor expression
《World Journal of Gastrointestinal Oncology》2024年第12期4700-4715,共16页Yuan-Chen Zhou Qian-Qian Wang Ge-Yu-Jia Zhou Teng-Fei Yin Dong-Yan Zhao Xi-Zhen Sun Chang Tan Lei Zhou Shu-Kun Yao 
Supported by National Key Development Plan for Precision Medicine Research,No.2017YFC0910002.
BACKGROUND The 5-year survival rate of patients with colorectal cancer(CRC)in China is only 56.9%,highlighting the need for new therapeutic drugs.Previous studies have shown that matrine exhibits antitumor effects by ...
关键词:Colorectal cancer Proteomics Shank-associated RH domain interactor MATRINE Apoptosis 
Anisotropy measurements and characterization of the Qingshankou shale
《Applied Geophysics》2024年第3期468-478,617,共12页Li Qing-feng Yan Xue-hong Yan Wei-lin Ren Li Wang Peng Han Jian-qiang Xia Xue Chen Hao 
supported by Major Science and Technology Special Project of China National Petroleum Corporation"Research on Large scale Storage and Production Increase and Exploration and Development Technology of Continental Shale Oil"(2023ZZ15)。
Qingshankou shale(Gulong area,China)exhibits strong acoustic anisotropy characteristics,posing significant challenges to its exploration and development.In this study,the five full elastic constants and multipole resp...
关键词:Transverse isotropy anisotropy parameter sonic logging group velocity phase velocity 
Primary repair for concurrent bilateral intertrochanteric fracture and femoral head necrosis with prolonged shank biologic total hip replacement: A case report and surgical techniques
《Chinese Journal of Traumatology》2023年第3期183-186,共4页Yuan-Jie Liu Jun-Tan Li Yu-Yang Gao Pei-Yan Guo Tian-Xu Dou Xu Li 
For the treatment of an intertrochanteric fracture combined with femoral head necrosis in middle-age patients,it has been controversial whether to perform fracture reduction and fixation first then total hip replaceme...
关键词:BILATERAL Primary hip replacement Femoral head necrosis Intertrochanteric fracture Greater trochanteric plate 
Dietary aflatoxin B1 induces abnormal deposition of melanin in the corium layer of the chicken shank possibly via promoting the expression of melanin synthesis-related genes
《Journal of Integrative Agriculture》2023年第6期1847-1856,共10页WANG Yong-li HUANG Chao YU Yang CAI Ri-chun SU Yong-chun CHEN Zhi-wu ZHENG Mai-qing CUI Huan-xian 
funded by the grants from the China Agriculture Research System of MOF and MARA (CARS-41);the Agricultural Science and Technology Innovation Program, China (ASTIP-IAS04)。
San-Huang chicken is a high-quality breed in China with yellow feather, claw and break. However, the abnormal phenomenon of the yellow shank turning into green shank of San-Huang chicken has been a concern, as it seri...
关键词:aflatoxin B1 melanin deposition skin color in shank CHICKEN negative effect 
突触后骨架蛋白与阿尔茨海默病被引量:1
《神经疾病与精神卫生》2022年第11期798-803,共6页王倩 霍明轩 赵瑞清 冯波 
山东省中医药科技发展计划(2019-0502)。
阿尔茨海默病(AD)是老年期最常见的慢性疾病之一,其患病率与年龄密切相关。突触作为神经元间信息传递的关键部位,与AD密切相关。突触结构与功能的丧失被认为是AD早期的标志。突触后密度蛋白-95、Shank和Homer蛋白是突触后主要骨架蛋白,...
关键词:阿尔茨海默病 突触后骨架蛋白 突触后密度蛋白-95 SHANK HOMER 综述 
NRXN-NLGN-SHANK通路基因变异在自闭症谱系障碍发病机制中的作用被引量:7
《中华医学遗传学杂志》2018年第5期753-756,共4页何龙楷 刘晓萍 宋燕燕 唐亚平 
国家自然科学基金(31671098)
自闭症谱系障碍(autism spectrum disorders,ASDs)是一种常见的神经发育障碍性疾病,发病机制不明。目前已知有超过100个基因与ASDs相关,其中一部分参与调控神经元突触的发展和功能。突触是神经元间进行信息传递的关键部位。ASDs患...
关键词:自闭症谱系障碍 突触 NRXN基因 NLGN基因 SHANK基因 
Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate被引量:12
《Cell Research》2017年第10期1293-1297,共5页Jiezhao Zheng Zhujun Li Rui Tian Youming Lu Xiangyu Guo Yong-hui Jiang Xiao-Jiang Li Yong Q Zhang 
We thank Drs Weixiang Guo, Xiaoming Wang and Zhiheng Xu for discussion, Ruxiao Xing, Xudong Liu and Jinquan Gao for technical assistance, Yafeng Luo (Guangzhou Yuanxi Biotech Co., Ltd) for animal resource and care, and Samuel Hulbert for critical reading of the manuscript. The project was supported by the Min- istry of Science and Technology of China (2014CB942803 and 2016YFA0501000), the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020400), and the National Natural Science Foundation of China (31110103907, 91332206 and 31490592).
Dear Editor, Despite substantial progress made toward under- standing the molecular changes contributing to autism spectrum disorders (ASD), the neuropathophysiology underlying ASD remains poorly understood [1, 2]....
关键词:非人灵长类动物 额叶皮层 神经 分子生物学 蛋白 突触 中断 水平分辨率 
SHANK家族与孤独症谱系障碍的关系研究进展
《中国儿童保健杂志》2016年第9期937-939,945,共4页孙志刚 李素水 薛曼 赵瑞申 
河北省科学技术研究与发展计划项目(122777118)
本文综述了SHANK家族与孤独症谱系障碍(ASD)的关系,主要是SHANK家族突变基因对突触功能的影响,尤其对兴奋性突触功能的影响。
关键词:孤独症谱系障碍 SHANK家族 突触功能 
Experimental and Numerical Investigation of an End Plate Connection with Using Long Shank SMA Bolts被引量:2
《Journal of Harbin Institute of Technology(New Series)》2015年第3期22-30,共9页Hongwei Ma Yongbing Zhu Michael C.H.Yam Yang Wang 
Sponsored by the National Natural Science Foundation of China(Grant No.50808084)
Superelastic shape memory alloys( SMAs) have the ability to recover their original shape after experiencing large strains. End-plate connection with using superelastic long shank SMA bolts is proposed in this paper. B...
关键词:finite element connection shape memory alloy DUCTILITY SELF-CENTERING 
The Redemption Hope and Persistence of Life on Shaw shank
《校园英语》2015年第20期253-253,共1页罗莎莎 
The film was about the caring and smart banker Andy Dufresne,who is falsely accused and convicted of the murder of his wife and her lover.He is sent to Shawshank prison in 1940,he met many fellow prisoners,including R...
关键词:ANDY HOPE PERSISTENCE REDEMPTION 
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