Background:With functionally heterogeneous cells,tumors comprise a complex ecosystem to promote tumor adaptability and evolution under strong selective pressure from the given microenvironment.Diversifying tumor cells...
Single-cell sequencing data has transformed the understanding of biological heterogeneity.While many flavors of single-cell sequencing have been developed,single-cell RNA sequencing(scRNA-seq)is currently the most pro...
supported by the Deutsche Forschungsgemeinschaft(MA6473/1-1,MA6473/2-1)
Many of our major crop species are polyploids, containing more than one genome or set of chromosomes. Polyploid crops present unique challenges, including difficulties in genome assembly, in discriminating between mul...
This research was funded in part by the National Natural Science Foundation of China(81602343 to Xin Wang);the Chinese Academy of Medical Sciences(CAMS)initiative Fund for Medical Sciences,China(2016-I2M-1-001 to Xiang Wang,2017-I2M-3-004 to Xin Wang);the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences,China(2018PT32013,2017PT32001 and 2016ZX310178 to Xin Wang);the Beijing Hope Run Special Fund,China(LC2017B15 to Xin Wang);the Capital’s Funds for Health Improvement and Research,China(2016-4-4026 to Xin Wang);Youth Research Fund of Beijing Tiantan Hospital,China(2017-YQN-09 to Wenyan Wang).
Breast cancer is one of the most common malignant tumors in women all over the world.Metastasis represents a major adverse progression of breast cancer,resulting in poor survival duration.Axillary lymph node metastasi...
Supported by the Ministry of Science and Technology Taiwan grant,No.MOST 106-2314-B-182A-019-MY3;the Chang Gung Foundation,No.CMRPG3E1321-2,No.IRB201601916B0,and No.IRB103-7448B
AIM To explore the correlation of metabolomics profiles ofgastric cancer(GC) with its chromosomal instability(CIN) status.METHODS Nineteen GC patients were classified as CIN and nonCIN type by The Cancer Genome Atlas ...
supported by the National Institutes of Health,USA (MH101054)
Schizophrenia(SCZ) is a complex and heterogeneous mental disorder that affects about 1% of global population. In recent years,considerable progress has been made in genetic studies of SCZ. A number of common variant...
The rationale of this work is based on recent evidences suggesting that: 1) both qualitative and quantitative β-lactoglobulin (β-LG) polymorphism may be found in bovine milk;2) quantitative polymorphisms are often t...