This research was supported by the National Natural Science Foundation of China(Nos.81603121,81673444,81973332);the Key Projects of Natural Science Research of Anhui Colleges and Universities(No.KJ2020A0158).
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovitis and the destruction of small joints. Emerging evidence shows that immunoglobulin D (IgD) stimulation induces T-cell activat...