This work was supported by the Ministry of Education(MOE)of Singapore(no.R-143-000-A93-112).
Chiral amines are synthetically versatile intermedi-ates used for the preparation of a wide range of biologically active compounds and drugs.Compared with the well-developed synthesis ofα-stereogenic amines,the estab...
A new protocol that enables asymmetric hydroaminomethylation of styrenes to afford chiral amines has been developed. Catalysed by an Rh-phosphine species and a chiral phosphoric acid, styrenes are converted into β-ch...
The hydroaminomethylation of 1-dodecene catalyzed by water soluble rhodium complex RhCl(CO)(TPPTS)2 in the presence of surfactant CTAB was investigated. High reactivity and selectivity for tertiary amine were achieved...