云南高校图书馆联盟文献共享服务平台- PRUCALOPRIDE

PRUCALOPRIDE: 作品数：10被引量：18H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：关奇刘冰李军涛曹凌薛靖更多>>; 相关机构：邯郸市中心医院首都医科大学附属北京佑安医院沈阳药科大学更多>>; 相关期刊：《World Journal of Gastrointestinal Endoscopy》《World Journal of Gastroenterology》《山东医药》《World Journal of Gastrointestinal Pharmacology and Therapeutics》更多>>

Prucalopride (Motegrity): 《中国药物化学杂志》2019年第6期498-498,共1页马德翊(编译) 关奇(审校); Prucalopride是由爱尔兰夏尔(Shire)公司研发的一种用于治疗成人慢性特发性便秘(CIC)的口服药物,于2018年12月14日获得美国FDA批准上市,其商品名为Motegrity[1]。Prucalopride的中文化学名称:4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)...; 关键词：治疗组安慰剂 PRUCALOPRIDE Motegrity

FDA咨询委员会支持批准夏尔慢性特发性便秘药物Prucalopride: 《临床合理用药杂志》2019年第2期172-172,共1页药品资讯网; 夏尔旗下Prucalopride获得美国FDA慢性特发性便秘咨询委员会的支持。FDA胃肠道药物咨询委员会一致投票认为,该药物的风险一收益结果支持其获批用于该适应证。咨询委员会还一致投票认为,Prucalopride治疗的心血管不良事件潜在风险已被夏...; 关键词：慢性特发性便秘美国FDA 药物咨询委员会心血管不良事件潜在风险胃肠道适应证

Prucalopride通过促进自噬抑制胶质瘤细胞U251增殖: 《现代肿瘤医学》2018年第9期1340-1344,共5页霍会永刘冰曹凌赵现曹妍薛靖王如科李军涛; 目的:研究Prucalopride对胶质瘤U251细胞增殖、自噬、凋亡的影响,并探讨其相关信号通路。方法:通过CCK8检测细胞增殖的变化;Transwell检测迁移和侵袭的变化;细胞流式实验、Western blot检测细胞凋亡的变化;Western blot检测自噬相关蛋白...; 关键词：PRUCALOPRIDE 脑胶质细胞瘤自噬 AKT/mTOR信号通路

5-羟色胺4受体激动剂Prucalopride对胃癌细胞增殖、迁移、侵袭、凋亡的影响: 《山东医药》2018年第2期30-32,共3页刘源王璐马超武聚山; 目的观察5-羟色胺(5-HT)4受体激动剂Prucalopride对胃癌细胞增殖、迁移、侵袭、凋亡的影响,并探讨其机制。方法将胃癌细胞MKN28随机分为观察组和对照组,分别予以10μmol/L的Prucaloprid及等体积DMSO处理24 h,分别采用CCK8、Transwell、...; 关键词：胃癌 PRUCALOPRIDE 5-羟色胺4受体激动剂细胞增殖细胞凋亡 PI3K信号通路

Efficacy of Prucalopride in bowel cleansing before colonoscopy:Results of a pilot study: 《World Journal of Gastrointestinal Endoscopy》2017年第11期558-560,共3页Vito Domenico Corleto Giulio Antonelli Chiara Coluccio Lucia D'Alba Emilio di Giulio; Colonoscopy is a crucial diagnostic instrument for colorectal cancer screening and an adequate bowel preparation is definitely decisive for the success of the procedure. Especially in elderly patients, bowel cleansing...; 关键词：Bowel cleansing COLONOSCOPY PRUCALOPRIDE Screening Colorectal cancer

Review of efficacy and safety of laxatives use in geriatrics被引量：5: 《World Journal of Gastrointestinal Pharmacology and Therapeutics》2016年第2期334-342,共9页Manhal Izzy Anju Malieckal Erin Little Sury Anand; AIM:To study the efficacy and safety of pharmacolo-gical treatment of constipation in geriatrics.METHODS:Pub Med,MEDLINE,google scholar,and Ovid were searched to identify human studies performed on the use of laxative...; 关键词：Chronic CONSTIPATION LAXATIVES ELDERLY LUBIPROSTONE Linaclotide PRUCALOPRIDE

Prucalopride-associated acute tubular necrosis被引量：2: 《World Journal of Clinical Cases》2014年第8期380-384,共5页Vithika Sivabalasundaram Flavio Habal David Cherney; Supported by A Kidney Foundation of Canada Scholarship and a Canadian Diabetes Association-KRESCENT Program Joint New Investigator Award and receives operating support from the Canadian Institutes of Health Research and the Heart and Stroke Foundation of Canada to Cherney D; We report the first case of acute renal failure secondary to prucalopride, a novel agent for the treatment of chronic constipation. The 75 years old male patient was initiated on prucalopride after many failed treatme...; 关键词：PRUCALOPRIDE Acute kidney tubular NECROSIS RENAL INSUFFICIENCY CONSTIPATION ADVERSE drug event

Novel therapies for constipation被引量：6: 《World Journal of Gastroenterology》2013年第45期8247-8251,共5页Sreedhari Thayalasekeran Hani Ali Her-Hsin Tsai; Constipation is a common medical problem and when standard laxatives fail it can be difficult to treat.Different aetiologies require tailored therapeutic approaches.Simple constipation may only require dietary manipul...; 关键词：CONSTIPATION PRUCALOPRIDE Linaclotide

Management of constipation in the elderly: Emerging therapeutic strategies被引量：5: 《World Journal of Gastroenterology》2008年第33期5226-5227,共2页Shailendra Kapoor; A number of new, novel strategies for managing constipation in the elderly have emerged over the past few years. Prucalopride is one such new agent that is highly effi cacious in managing chronic constipation. In fact...; 关键词：CONSTIPATION PRUCALOPRIDE LUBIPROSTONE NEOSTIGMINE METHYLNALTREXONE

Effect of enterokinetic prucalopride on intestinal motility in fast rats被引量：1: 《World Journal of Gastroenterology》2003年第9期2065-2067,共3页Hui-Bin Qi Jin-Yan Luo Xin Liu Department of Gastroenterology,Second Hospital of Xi’an Jiaotong University,Xi’an 710004,Shannxi Province,China; AIM: To evaluate the effects of prucalopride on intestinal prokinetic activity in fast rats and to provide experimental basis for clinical treatrnent of gastrointestinal motility diseases.METHODS: Gastrointestinal pro...; 关键词：普鲁必利胃肠运动性疾病药物治疗动物实验

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