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Transient chemical-mediated epigenetic modulation confers unrestricted lineage potential on human primed pluripotent stem cells: 《Science China(Life Sciences)》2025年第4期1084-1101,共18页Shi Chen Yuanyuan He Lejun Lv Bei Liu Cheng Li Hongkui Deng Jun Xu; supported by the National Key Research and Development Program of China(2021YFA1100300);the National Natural Science Foundation of China(32288102,32370843 and 32025006)Part of the data analysis was performed on the High Performance Computing Platform of the Center for Life Sciences,Peking University。; Human primed pluripotent stem cells are capable of generating all the embryonic lineages.However,their extraembryonic trophectoderm potentials are limited.It remains unclear how to expand their developmental potential...; 关键词：trophectoderm lineages human primed pluripotent stem cells epigenetic regulation small molecules

Mitogenomic variation in the Black-throated Tit(Aegithalos concinnus):Conserved structure,concerted evolution of duplicate control regions and multiple distinct evolutionary lineages: 《Avian Research》2024年第4期422-430,共9页Chuanyin Dai Fumin Lei; financially supported by the National Natural Science Foundation of China(Grant No.32060310);a grant from the Department of Education of Guangxi.; The mitochondrial genome is a prominent research topic due to its indispensable role in organisms and its application in many research disciplines.However,few studies have investigated intraspecies mitogenomic variati...; 关键词：Aegithalos concinnus Concerted evolution Intraspecies variation Lineage diversification Mitochondrial genome

Shifts in reproductive strategies in the evolutionary trajectory of plant lineages: 《Science China(Life Sciences)》2024年第11期2499-2510,共12页Xin-Jian Zhang Xian-Han Huang Jacob BLandis Quan-Sheng Fu Jun-Tong Chen Peng-Rui Luo Li-Juan Li Heng-Yi Lu Hang Sun Tao Deng; supported by the Second Tibetan Plateau Scientific Expedition and Research(STEP)program(2019QZKK0502);the National Natural Science Foundation of China(32322006);the Key Projects of the Joint Fund of the National Natural Science Foundation of China(U1802232);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2019382);the International Partnership Program of Chinese Academy of Sciences(151853KYSB20180009);Yunnan Science and Technology Project(YNWR-QNBJ-2019-033,202103AF140005,202305AM070005);Project of Background Resources Survey in Shennongjia National Park(SNJNP2022003).; Understanding the maintenance and shift in reproductive strategies is a fundamental question in evolutionary research.Although many efforts have been made to compare different reproductive strategies,the association b...; 关键词：SAXIFRAGACEAE DIVERSIFICATION reproduction CLONALITY phenotype NICHE

A bivalent Delta/BA.5 mRNA vaccine elicits broad immune responses against various lineages of SARS-CoV-2 including JN.1: 《Virologica Sinica》2024年第5期833-835,共3页Kangyin Li Qi Liu Yan Wu Bihao Wu Shaohong Chen Xinghai Zhang Xiaoying Jia Rui Gong Yucai Peng Huajun Zhang Sandra Chiu; Dear Editor,The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has posed a continuous threat to global public health.A number of vaccines,such as inactivated vaccines,mRNA vaccines,recombinant ade...; 关键词：acute RESPIRATORY

Cretaceous crown male ant reveals the rise of modern lineages: 《Zoological Research》2024年第5期983-989,共7页Qiong Wu Alexander G.Radchenko Michael S.Engel Xiao-Qin Li Hong-Ru Yang Xing-Ru Li Chung-Kun Shih Dong Ren Tai-Ping Gao; supported by the National Natural Science Foundation of China(32270467,32020103006);National Research Foundation of Ukraine(2020/02/0369 to A.G.R.);CONCYTEC through the PROCIENCIA“Interinstitutional Alliances for Doctorate Programs”(PE501084299-2023-PROCIENCIA-BM to M.S.E.)。; Most described Mesozoic ants belong to stem groups that existed only during the Cretaceous period.Previously,the earliest known crown ants were dated to the Turonian(Late Cretaceous,ca.94-90 million years ago(Ma))depo...; 关键词：FORMICIDAE FORMICINAE Morphology Taxonomy Antiquiformica alata PALEONTOLOGY Kachin amber

Computational insights into CRISP3 downregulation in cervical cancer and its cervical lineages pattern: 《Precision Clinical Medicine》2024年第3期246-256,共11页Ricardo Cesar Cintra Andres Galindo Céspedes Mércia Patricia Ferreira Conceicao Maiza Vitoria Aguiar Silva OliveiraAlessandro Buron Deisiane Rodrigues das Neves Fabio Alves Moraes Olinda Maria Gamarra Daniel Rodrigues de Bastos; Background:Cysteine-rich secretory protein 3(CRISP3)emerges as a potential biomarker in the study of many cancers,including cervical cancer(CC).This study aimed to analyze the expression pattern of CRISP3 in CC patien...; 关键词：cervical cancer uterine cervical carcinoma CRISP3 biomarkers in cancer PROGNOSIS

Genetic and pathogenic characterization of new infectious bronchitis virus strains in the GVI-1 and GI-19 lineages isolated in central China: 《Journal of Integrative Agriculture》2024年第7期2407-2420,共14页Yuhan Yang Dou Wang Yaning Bai Wenyan Huang Shimin Gao Xingchen Wu Ying Wang Jianle Ren Jinxin He Lin Jin Mingming Hu Zhiwei Wang Zhongbing Wang Haili Ma Junping Li Libin Liang; supported by the National Natural Science Foundation of China(32202788);the Special Research Fund of Shanxi Agricultural University for High-level Talents,China(2021XG004);the Fund for Shanxi“1331 Project”,China(20211331-13);the Shanxi Province Excellent Doctoral Work Award-Scientific Research Project,China(SXBYKY2021063,SXBYKY2021005,and SXBYKY 2022014);the earmarked fund for Modern Agro-industry Technology Research System of Shanxi Province,China(2023CYJSTX15-13);the Fundamental Research Program of Shanxi Province,China(202103021224156)。; Avian infectious bronchitis(IB)is a highly contagious infectious disease caused by infectious bronchitis virus(IBV),which is prevalent in many countries worldwide and causes serious harm to the poultry industry.At pre...; 关键词：infectious bronchitis virus GI-19 lineage GVI-1 lineage complete genome recombination PATHOGENICITY

Safety,immunogenicity,and preliminary efficacy of a randomized clinical trial ofomicron XBB.1.5-containing bivalent mRNA vaccine: 《hLife》2024年第3期113-125,共13页Xuanjing Yu Wei Yang Wei Li Na Wan Guanghong Yan Zumi Zhou Xiao Zhu Wei Su Yani Li Chenyu Xing Sifan Duan Houze Yu Xinshuai Zhao Chunmei Li Taicheng Zhou Dingyun You Jia Wei Zijie Zhang; supported by a grant(2023YFC2307600,to Z.J.Z.)from the Na-tional Key Research and Development Program of China;a grant(202102AA100051,to Z.J.Z.)from the Yunnan Provincial Sci-ence and Technology Department,China;a grant(H-2018102,to J.W.)from the High-level Health Technical Personnel Project of Yunnan Province,China;a grant(2022SCP001,to Z.J.Z.)from the Spring City Plan:The High-level Talent Promotion and Training Project of Kunming;and a grant(32371000,to C.M.L.)from the National Natural Science Foundation of China.; Periodically updating coronavirus disease 19(COVID-19)vaccines that offer broad-spectrum protection is needed giventhe strong immune evasion by the circulating omicron sublineages.The effectiveness of prototype and BA...; 关键词：severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) JN.1 XBB lineages coronavirus disease19(COVID-19)vaccine mRNA bivalent vaccine randomized clinical trial

Highly divergent sympatric lineages of Leptotila verreauxi(Aves:Columbidae)suggest a secondary contact area in the Isthmus of Tehuantepec,Mexico: 《Avian Research》2024年第1期12-21,共10页Orlando J.Espinosa-Chávez Adolfo G.Navarro-Sigüenza Hernando Rodríguez-Correa Luis A.Sánchez-González; the financial support for this study by PAPIIT-UNAM grant(IN222817)to LAS-G;the Fran?ois Vuilleumier Fund for Neotropical Bird Research from the Neotropical Ornithological Society(NOS)awarded to OJE-C。; Due to a complex geological and biotic history,the Isthmus of Tehuantepec(IT),has been long recognized as a driver for the evolutionary divergence of numerous lowland and highland taxa.Widely distributed in the lowlan...; 关键词：Biogeographical boundary Humid and dry forests Isthmus of Tehuantepec PHYLOGEOGRAPHY Secondary contact

Dynamic transcriptional programs define distinct mammalian cortical lineages: 《Neural Regeneration Research》2024年第2期387-389,共3页Tanzila Mukhtar Verdon Taylor; supported by the SystemsX-NeuroStemX and Swiss National Science Foundation,No.51RT-0_145728(to VT and TM)。; The cerebral cortex is composed of billions of neurons and glia that are generated sequentially during corticogenesis.These cells are generated in an organized fashion during development.At early stages of brain devel...; 关键词：CORTEX cerebral development

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