OPTOGENETICS

作品数：74被引量：138H指数：7
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相关领域：医药卫生生物学更多>>
相关作者：黄志力王立平更多>>
相关机构：上海医学院香港理工大学中国科学院南洋理工大学更多>>
相关期刊：《National Science Review》《Engineering》《Journal of Innovative Optical Health Sciences》《aBIOTECH》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划以色列科学基金中国博士后科学基金更多>>
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Optogenetic activation of glutamatergic neu⁃rons in somatosensory cortex promotes remy⁃elination in ischemic vascular dementia
《中国药理学与毒理学杂志》2021年第9期696-697,共2页ZHOU Yi-ting AN Da-dao XU Yi-xin ZHOU Ying LI Qing-qing ZHANG Xiang-nan WANG Yi LOU Min CHEN Zhong HU Wei-wei 
OBJECTIVE Chronic cerebral hy⁃poperfusion can lead to progressive demyelin⁃ation and ischemic vascular dementia,yet there are no effective treatments.METHODS Magnetic resonance imaging was employed in patients with wh...
关键词：OPTOGENETICS glutamatergic neurons ischemic vascular dementia 
Optogenetic dissection of neuronal circuit underlying temporal lobe epilepsy
《中国药理学与毒理学杂志》2018年第9期736-736,共1页WANG Yi CHEN Zhong 
National Natural Science Foundation of China(91332202;81221003;81603084).
Temporal lobe epilepsy(TLE) is a common type of epilepsy and is not well controlled by current treatments.The frequent failure to treat TLE may be due to our lack of precise cellular/circuit mechanisms underlying TLE....
关键词：EPILEPSY NEURONAL CIRCUIT depolarized GABAERGIC signaling OPTOGENETICS 
Genetically engineered systems revealed the roles of basal ganglia in sleep-wake regulation被引量：1
《中国药理学与毒理学杂志》2017年第5期470-470,共1页黄志力 
The basal ganglia(BG) act as a cohesive functional unit that regulates motor function,habit formation,and reward/addictive behaviors. However,it is still not well understood how the BG maintains wakefulness and suppre...
关键词：adeno-associated virus OPTOGENETICS DREADD basal ganglia sleep-wake regulation 
颞叶癫痫异常神经环路分析(英文)
《中国药理学与毒理学杂志》2017年第5期451-451,共1页汪仪 徐层林 陈忠 
The project supported by National Natural Science Foundation of China(91332202,81630098)
OBJECTIVE Temporal lobe epilepsy(TLE) is one of the most common types of human epilepsy,and they are often resistant to current treatments. METHODS By using optogenetic,electrophysiological,imaging and pharmacology st...
关键词：EPILEPSY neural circuits brain stimulation OPTOGENETICS electro-responsive 
Modulation of abnormal neuronal circuit in temporal lobe epilepsy
《中国药理学与毒理学杂志》2016年第10期1026-1027,共2页WANG Yi YING Xiao-ying CHEN Bin XU Ceng-lin CHEN Zhong 
The project supportedp by National Natural Science Foundation of China(91332202,81221003)
OBJECTIVE Temporal lobe epilepsy(TLE)is one of the most common types of human epilepsy,and they are often resistant to current treatments.METHODS By using optogenetic,electrophysiological,imaging and pharmacology stra...
关键词：EPILEPSY neural circuits brain stimulation OPTOGENETICS electro-responsive 
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