MABS

作品数:40被引量:45H指数:3
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相关领域:医药卫生农业科学更多>>
相关作者:任秉银任阳李文博任亮余卓平更多>>
相关机构:宁波坚锋新材料有限公司哈尔滨工业大学威高集团有限公司长春工业大学更多>>
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相关基金:国家自然科学基金中国石油天然气集团公司科技项目上海市教育委员会重点学科基金更多>>
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Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1
《hLife》2024年第10期527-541,共15页Qi Pan Xiaomin Xing Jianhai Yu Qiang Chen Haizhan Jiao Wanqin Zhang Yingfen Wen Ming Gao Wei Zhao Lei Yu Hongli Hu 
supported by grants from the National Natural Science Foundation of China(81971924 to L.Y.and 32370146 to W.Z.);Guangzhou Municipal Science and Technology Bureau(2023A03J0791 to L.Y.);Guangdong Science and Technology Program(2021B1212030014 to W.Z.);Guangdong Basic and Applied Basic Research Fund Enterprise Joint Fund(2021A1515220017 to W.Z.);Medical Scientific Research Foundation of Guangdong Province(B2022112 to J.Y.),Shenzhen Science and Technology Innovation Committee(JCYJ20210324131802008 to H.H.);Ganghong Young Scholar Development Fund(to H.H.);the Shenzhen-Hong Kong Cooperation Zone for Technology and Innovation(HZQB-KCZYB-2020056 to H.H.);the Kobilka Institute of Innovative Drug Discovery and Presidential Fellowship and University Development Fund at the Chinese University of Hong Kong,Shenzhen(to H.H.,H.J.,and Q.C.);Presidential Fellowship at the Chinese University of Hong Kong,Shenzhen(to Q.P.and W.Z.)。
Antibodies targeting non-structural protein 1(NS1)confer protection against Zika virus(ZIKV).Although monoclonal an-tibodies(MAbs)3G2 and 4B8 are more potent than MAb 4F10 in suppressing ZIKV infection in neonatal mic...
关键词:Zika virus(ZIKV) non-structural protein 1(NS1) monoclonal antibodies(MAbs) EPITOPES 
CGRP-mAbs预防和治疗难治性偏头痛疗效与安全性的Meta分析
《现代医学》2024年第8期1179-1186,共8页周璐瑶 李斌 李媛媛 毕晓莹 黎佳思 
国家自然科学基金面上项目(81971242);长海医院教学成果立项培育项目(CHPY2021B03)。
目的:系统评价3种降钙素基因相关肽单克隆抗体(CGRP-mAbs)在真实世界研究和随机对照试验(RCT)中预防性治疗难治性偏头痛的有效性和安全性。方法:计算机检索中国知网、万方、PubMed、Cochrane Library、Embase,收集关于CGRP-mAbs治疗难...
关键词:CGRP-mAbs 降钙素基因相关肽 偏头痛 META分析 
TPU/MABS合金的耐乙醇和耐碘伏性能研究
《橡胶工业》2024年第7期500-506,共7页尹云山 陈帅 李晓明 尹立刚 任方正 陈家悦 胡水 
国家重点研发计划项目(2020YFC1106901)。
制备不同共混比的聚醚型和聚酯型聚氨酯(TPU)/甲基丙烯酸甲酯-丙烯腈-丁二烯-苯乙烯共聚物(MABS)合金,对TPU/MABS合金的耐乙醇和耐碘伏性能进行研究。结果表明:经乙醇和碘伏浸泡24 h的MABS在垂直于应力方向出现大量的裂纹甚至断裂;随着...
关键词:聚氨酯 甲基丙烯酸甲酯-丙烯腈-丁二烯-苯乙烯共聚物 耐乙醇性能 耐碘伏性能 
胶含量对本体MABS树脂结构性能的影响被引量:2
《塑料科技》2023年第4期30-35,共6页李欣 王雅群 宋任展 朱坤良 刘丰嘉 杨俊晖 王益波 林润雄 
采用溶聚丁苯橡胶、苯乙烯、丙烯腈、甲基丙烯酸甲酯单体,通过本体聚合制备MABS树脂,调整配方中橡胶含量,探究胶含量对制品的微观结构、力学性能、加工流动性以及透明性的影响,以期得到合适的胶含量。结果表明:胶含量的增加使体系黏度...
关键词:本体聚合 MABS树脂 胶含量 力学性能 加工流动性 透明性 
Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine
《Medicine in Novel Technology and Devices》2022年第3期144-147,共4页Yuyan Ling Yuxuan Dong Qirui Li Doudou Huang Zhihui Li Meijuan Chen 
Traditional Chinese and Western Medicine Clinical Medicine Brand Construction Project of Jiangsu Higher Education Institutions(Phase II),No:2020PPZXL261.
The mortality rate of the recent global pandemic corona virus disease 2019(COVID-19)is currently as high as 7%.The SARS-CoV-2 virus is the culprit behind COVID-19.SARS-CoV-2 is an enveloped single-stranded RNA virus,t...
关键词:Monoclonal antibody(mAbs) Corona virus disease 2019(COVID-19) S protein N protein Traditional Chinese medicine 
抗GⅡ.3型诺如病毒阻断型单克隆抗体的制备和鉴定
《病毒学报》2022年第1期98-105,共8页霍玉奇 郑礼钧 刘金瑾 
诺如病毒(norovirus,NoV)是引起非细菌性急性肠胃炎的主要病原体之一。目前国内外还没有关于抗GⅡ.3NoV组织血型抗原(histo-blood group antigens,HBGAs)阻断型单克隆抗体(monoclonal antibody,mAb)的报道,本研究制备了抗GⅡ.3型NoV HBG...
关键词:GⅡ.3型诺如病毒(NoV) 组织血型抗原(HBGAs) 阻断型单克隆抗体(blocking mAbs) 多肽 表位 
Pushing the limit of thermal conductivity of MAX borides and MABs被引量:2
《Journal of Materials Science & Technology》2022年第2期79-88,共10页Shaohan Li Weiwei Sun Yi Luo Jin Yu Litao Sun Bao-Tian Wang Ji-Xuan Liu Guo-Jun Zhang Igor Di Marco 
the National Natural Science Foundation of China(No.51902052);partially supported by“the Fundamental Research Funds for the Central Universities”;supported by appointments to the JRG program at the APCTP through the Science and Technology Promotion Fund and Lottery Fund of the Korean Government,the Korean Local Governments,Gyeongsangbuk-do Province and Pohang City;partially funded by the Swedish Research Council through grant agreement no.2018-05973 for providing the facility support on the numerical calculations in this paper。
The emergence of MAX borides as well as MAB phases attracted great attention because of the renewable developments of ternary ceramics and offering great opportunities in potential applications.However,the number of b...
关键词:MAX and MAB phases Density functional theory calculation Structure searching Thermal conductivity 
TPU增韧MABS的研究被引量:1
《化学研究》2021年第1期68-71,77,共5页宋修山 尹云山 尹立刚 陈家悦 李晓明 
利用双螺杆挤出机制备聚氨酯和甲基丙烯酸甲酯—丙烯腈-丁二烯-苯乙烯树脂熔融共混物(合金)。研究TPU的类型以及含量对TPU/MABS合金的透光率、力学性能和缺口冲击强度影响。结果表明:TPU/MABS合金可以保持较好透明性,随TPU含量的增加,...
关键词:聚氨酯 甲基丙烯酸甲酯-丙烯腈-丁二烯-苯乙烯 增韧 
Human Monoclonal Antibodies: On the Menu of Targeted Therapeutics Against COVID-19被引量:1
《Virologica Sinica》2020年第6期713-724,共12页Junsen Chen Rui Huang Yiwen Nie Xinyue Wen Ying Wu 
supported by Grants from the National Science and Technology Major Project (Grant No.2018ZX10733403)。
Coronavirus disease 2019(COVID-19), reminiscent of the severe acute respiratory syndrome(SARS) outbreak in 2003,has been a tragic disaster to people all over the world. As there is no specific drug for COVID-19, neutr...
关键词:COVID-19 MABS S glycoprotein EPITOPES 
Applications of M/N/C analogue catalysts in PEM fuel cells and metal-air/oxygen batteries:Status quo,challenges and perspectives
《Progress in Natural Science:Materials International》2020年第6期807-814,共8页Bin Chi Xiaorong Zhang Mingrui Liu Shijie Jiang Shijun Liao 
supported by the National Key Research and Development Program of China(Project Nos.2017YFB0102900 and 2016YFB0101201);the National Natural Science Foundation of China(NSFC Project Nos.21476088 and 21776105);the Guangdong Provincial Department of Science and Technology(Project No.2015B010106012);the Guangzhou Science,Technology and Innovation Committee(Project Nos.201504281614372 and 2016GJ006)。
To meet the sharp increase in demand for clean and renewable energy,it is necessary to develop new energyconversion and storage technologies,such as proton exchange membrane fuel cells(PEMFCs)and metal-air/oxygen batt...
关键词:PEM fuel cell MABS M/N/C catalysts Oxygen reaction 
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