CHECKPOINT

作品数:720被引量:1395H指数:15
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相关领域:医药卫生自动化与计算机技术更多>>
相关作者:段红刘穆进张彩田志刚景年财更多>>
相关机构:上海大学华中科技大学国防科学技术大学CheckPoint软件技术有限公司更多>>
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相关基金:国家自然科学基金中国博士后科学基金广东省自然科学基金国家重点基础研究发展计划更多>>
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  • 期刊=World Journal of Clinical Casesx
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Vitiligo-like rash in a patient with lung cancer caused by sintilimab: A case report
《World Journal of Clinical Cases》2025年第14期32-37,共6页Xiao-Ming Mao Wei-Hua Wang 
BACKGROUND This article discusses a case involving a 63-year-old man with non-small cell lung cancer,who was treated with a combination of chemotherapy and immunothe-rapy.The patient was treated with five cycles of ch...
关键词:Lung cancer VITILIGO Immune checkpoint inhibitor Sintilimab Case report 
Cytokine release syndrome induced by anti-programmed death-1 treatment in a psoriasis patient:A dark side of immune checkpoint inhibitors
《World Journal of Clinical Cases》2024年第35期6782-6790,共9页JoséLuis Maldonado-García Ana Fragozo Lenin Pavón 
Supported by Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz,No.NC23189.0.
In recent years,cancer immunotherapy has introduced novel treatments,such as monoclonal antibodies,which have facilitated targeted therapies against tumor cells.Programmed death-1(PD-1)is an immune checkpoint expresse...
关键词:Immune checkpoints inhibitors Programmed death-1 Cancer immunotherapy PSORIASIS Cytokine release syndrome Immune-related adverse events 
Toripalimab in combination with chemotherapy effectively suppresses local recurrence and metastatic sarcomatoid renal cell carcinoma:A case report
《World Journal of Clinical Cases》2024年第28期6230-6236,共7页Ming-Zhu Gao Nian-Fei Wang Jin-You Wang Li Ma Yu-Cai Yang 
The Health Research Program of Anhui Province,China,No.AHWJ2022b048;The Research Foundation of Anhui Medical University,China,No.2021xkj164;The Clinical Scientific Research Cultivation Project of the Second Affiliated Hospital of Anhui Medical University,China,No.2021LCZD04.
BACKGROUND Sarcomatoid renal cell carcinoma(SRCC)is a rare variant of renal cell carcinoma associated with an unfavorable prognosis.The efficacy of conventional chemo-therapy and targeted therapies are limited,whereas...
关键词:Renal cell carcinoma Sarcomatoid dedifferentiation Immune checkpoint inhibitor CHEMOTHERAPY Case report 
New strategies in the diagnosis and treatment of immune-checkpoint inhibitor-mediated colitis
《World Journal of Clinical Cases》2024年第6期1050-1062,共13页Tsvetelina Velikova Boris Krastev Milena Gulinac Miroslav Zashev Vasko Graklanov Milena Peruhova 
Supported by the European Union-NextGenerationEU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,No.BG-RRP-2.004-0008.
Immune-checkpoint inhibitor-mediated colitis(IMC)is an increasingly recognized adverse event in cancer immunotherapy,particularly associated with immune checkpoint inhibitors(ICIs)such as anti-cytotoxic T-lymphocyte a...
关键词:Immune-checkpoint inhibitors Immune-checkpoint inhibitor-mediated colitis Inhibitor-mediated colitis management Immunotherapy-associated colitis Checkpoint inhibitor-induced colitis Gastrointestinal adverse effects Checkpoint inhibitor toxicity Inhibitor-mediated colitis therapy 
Pulmonary reversed halo cycles and consolidations after immunotherapy:A case report
《World Journal of Clinical Cases》2023年第28期6938-6942,共5页Hong Suo Yu-Jie Shi Zhao-Di Huang Kai Xu Hui Huang 
Supported by National High Level Hospital Clinical Research Funding,No.2022-PUMCH-C-069 and No.2022-PUMCH-A-009.
BACKGROUND Immune checkpoint inhibitor-associated interstitial lung disease(ICI-ILD)and opportunistic pneumonias are the main pulmonary complications during immunotherapy for malignancies.The organizing pneumonia(OP)p...
关键词:Reversed halo cycles Consolidations IMMUNOTHERAPY TUBERCULOSIS Checkpoint inhibitor associated interstitial lung disease Case report 
Zimberelimab plus chemotherapy as the first-line treatment of malignant peritoneal mesothelioma:A case report and review of literature
《World Journal of Clinical Cases》2023年第22期5296-5302,共7页Xiao-Dong Peng Zhen-Yu You Lian-Xiang He Qi Deng 
BACKGROUND Malignant peritoneal mesothelioma(MPeM)is a rare cancer with a poor prognosis at advanced stage,and the standard first-line treatment for inoperable patients is chemotherapy.Although combining programmed ce...
关键词:Malignant peritoneal mesothelioma Immune checkpoint inhibitors IMMUNOTHERAPY Zimberelimab CHEMOTHERAPY Case report 
Nivolumab-induced tumour-like gastritis:A case report
《World Journal of Clinical Cases》2023年第18期4350-4359,共10页Elena Cijauskaite Edita Kazenaite Sandra Strainiene Goda Sadauskaite Benediktas Kurlinkus 
BACKGROUND Immune checkpoint inhibitors are one of the modern treatment methods for advanced malignancies.However,this group of medications is also associated with various immune-related adverse events,such as colitis...
关键词:Nivolumab Immune checkpoint inhibitors Tumour-like gastritis Proton pump inhibitors Case report 
Immune checkpoint inhibitor therapy-induced autoimmune polyendocrine syndrome typeⅡand Crohn's disease:A case report
《World Journal of Clinical Cases》2023年第14期3267-3274,共8页Mei-Juan Gao Yan Xu Wen-Bo Wang 
BACKGROUND The development of immune checkpoint inhibitors(ICIs)has heralded a new era in cancer treatment,enabling the possibility of long-term survival in patients with metastatic disease.Unfortunately,ICIs are incr...
关键词:Immune checkpoint inhibitor Programmed cell death protein 1 ligand Autoimmune polyendocrine syndrome type II Type 1 diabetes mellitus Thyroiditis Crohn’s disease Case report 
Immune-related adverse events induced by programmed death protein-1 inhibitors from the perspective of lymphoma immunotherapy
《World Journal of Clinical Cases》2023年第7期1458-1466,共9页Yong-Zhe Hou Qin Zhang Hai Bai Tao Wu Ya-Jie Chen 
the 2022 Project of Innovation Foundation of Outstanding Graduate Students of Gansu Province;the Graduate Innovation Foundation of Major Project of Education Department of Gansu Province,No.lccx2021001;the Gansu Provincial Science and Technology Plan Project Assignment(Innovation Base and Talent Plan),No.21JR7RA013;the Gansu Province Innovation Base and Talent Plan(Gansu Province Leukemia Clinical Research Center),No.21JR7RA015;the 2022 Hospital Project of The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army,No.2022yxky015.
Lymphoma,which is highly malignant,stems from lymph nodes and lymphoid tissue.Lymphoma cells express programmed death-ligand 1/2(PD-L1/PD-L2),which binds with programmed cell death 1 protein(PD-1)to establish inhibito...
关键词:LYMPHOMA Programmed cell death 1 receptor Immune checkpoint inhibitors Immune-related adverse events Nivolumab Pembrolizumab 
Multidisciplinary treatment of a patient with severe immune checkpoint inhibitor-induced colitis:A case report
《World Journal of Clinical Cases》2022年第35期13108-13114,共7页Lu Lu Li Sha Yu Feng Liang Yan 
Shanghai Municipal Health Commission,Shanghai Municipal Administrator of Traditional Chinese Medicine,No.ZY(2021-2023)-0201-02.
BACKGROUND Immune checkpoint inhibitors(ICIs)are a new class of antitumor drugs that have been approved to treat a variety of malignant tumors.However,the occurrence of immune related adverse events(irAEs)has become a...
关键词:Immune checkpoint inhibitor COLITIS Programmed cell death ligand 1 INFLIXIMAB Laparoscopic surgery Case report 
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