CHECKPOINT

作品数:720被引量:1395H指数:15
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相关领域:医药卫生自动化与计算机技术更多>>
相关作者:段红刘穆进张彩田志刚景年财更多>>
相关机构:上海大学华中科技大学国防科学技术大学CheckPoint软件技术有限公司更多>>
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相关基金:国家自然科学基金中国博士后科学基金广东省自然科学基金国家重点基础研究发展计划更多>>
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Vitiligo-like rash in a patient with lung cancer caused by sintilimab: A case report
《World Journal of Clinical Cases》2025年第14期32-37,共6页Xiao-Ming Mao Wei-Hua Wang 
BACKGROUND This article discusses a case involving a 63-year-old man with non-small cell lung cancer,who was treated with a combination of chemotherapy and immunothe-rapy.The patient was treated with five cycles of ch...
关键词:Lung cancer VITILIGO Immune checkpoint inhibitor Sintilimab Case report 
Systemic chemotherapy improves outcome of hepatocellular carcinoma patients treated with transarterial chemoembolization
《Hepatobiliary & Pancreatic Diseases International》2025年第2期157-163,共7页Wei-Chen Zhang Ke-Yi Du Song-Feng Yu Xue-E Guo Han-Xi Yu Dong-Yan Wu Cheng Pan Cheng Zhang Jian Wu Li-Fang Bian Lin-Ping Cao Jun Yu 
supported by grants from the National Natural Science Foundation of China(82270682);the Natural Science Foundation of Zhejiang Province(LQ21H030007 and LQ20H30006)。
Background:Transarterial chemoembolization(TACE)based neoadjuvant therapy was proven effective in hepatocellular carcinoma(HCC).Recently,tyrosine kinase inhibitors(TKIs)and immune checkpoint inhibitors(ICIs)also showe...
关键词:Neoadjuvant therapy Hepatocellular carcinoma Major pathologic response Transarterial chemoembolization Tyrosine kinase inhibitors Immune checkpoint inhibitors 
Lycii Radicis Cortex suppresses the growth of non-small cell lung cancer via enhancing the anti-tumor immunity
《Food Science and Human Wellness》2025年第2期651-661,共11页Heng Yin Meng Liu Yaling Zhao Haitao Wu Danna Zheng Zhenhui Guo Ying Zhou Shaofeng Wu Chuanbing Chen Lei Zhang Shanshan Song Yanli He Ren Zhang 
supported by Natural Science Foundation of Guangdong Province,China(2022A1515011575);National Natural Science Foundation of China,China(81873154);President Foundation of Integrated Hospital of Traditional Chinese Medicine,Southern Medical University,China(1202103010)。
Lycii Radicis Cortex(LRC)is a medicinal and food homologous plant with various pharmacological activities,including anti-tumor effects.This study explores the anti-tumor effect of LRC on non-small cell lung cancer(NSC...
关键词:Lycii Radicis Cortex Non-small cell lung cancer PD-L1 Immune checkpoint 
Combining anti-PD-1 antibodies with surufatinib for gastrointestinal neuroendocrine carcinoma: Two cases report and review of literature
《World Journal of Clinical Oncology》2025年第4期298-311,共14页Lou-Lu Gao Dong-Ni Gao Hong-Tu Yuan Wen-Qiang Chen Jing Yang Jie-Qiong Peng 
BACKGROUNDGastrointestinal neuroendocrine carcinoma (GI NEC) has a low incidence rate andpoor prognosis. Most patients already have metastatic disease when they arediagnosed. Platinum chemotherapy is the main means of...
关键词:Gastrointestinal neuroendocrine carcinoma Immune checkpoint inhibitors Angiogenesis inhibitors Combination therapy Case report 
Efficacy and safety of radiotherapy in patients with microsatellite stable or proficient mismatch repair colorectal cancer liver metastasis
《World Journal of Gastrointestinal Oncology》2025年第3期59-68,共10页Jie Ni Chu-Gen Wan Zi-Qi Sui 
BACKGROUND Colorectal cancer is one of the malignant tumors with a high incidence and mortality rate globally,and the occurrence of liver metastasis significantly affects patient survival prognosis.In recent years,the...
关键词:Microsatellite stability Proficient mismatch repair Colorectal cancer Liver metastasis RADIOTHERAPY Immune checkpoint inhibitors Tyrosine kinase inhibitor Efficacy Safety 
Neoadjuvant therapy:Dawn of reducing the high post-surgery recurrence rate of hepatocellular carcinoma
《World Journal of Gastrointestinal Surgery》2025年第3期57-68,共12页Xiao-Dong Zhang Lu-Yi Zhang Jia-Liang Luo Ke-Heng Yu Ke-Lei Zhu 
Supported by the Zhejiang Provincial Medical and Health Science and Technology Plan,No.2022ZH050;the Health Science and Technology Project of Yinzhou District,No.2023Y03.
The high postoperative recurrence rate remains a major challenge in the treatment of hepatocellular carcinoma(HCC)following resection.Increasing research has been delved into investigating the role of neoadjuvant ther...
关键词:Hepatocellular carcinoma Neoadjuvant therapy Locoregional therapy Molecularly targeted drug Immune checkpoint inhibitor 
Mapping the landscape of gastric cancer immunotherapy:Bibliometric insights into advances and hotspots
《World Journal of Gastrointestinal Oncology》2025年第3期349-370,共22页Zhen Yuan Jing-Hang Wang Hao Cui Shu-Yuan Wang Bo Wei Jian-Xin Cui 
National Natural Science Foundation of China,No.82073192 and No.82273231;Beijing Science and Technology Program,No.Z221100007422125;The Chinese People's Liberation Army General Hospital Medical Engineering Laboratory Project,No.2022SYSZZKY16.
BACKGROUND Immunotherapy has surfaced as a promising therapeutic modality for gastric cancer(GC).A comprehensive review of advancements,current status,and research trends in GC immunotherapy is essential to inform fut...
关键词:BIBLIOMETRICS Gastric cancer IMMUNOTHERAPY Immune checkpoint inhibitor Tumor microenvironment 
Safety and effectiveness of induction chemoimmunotherapy followed by definitive radiotherapy or concurrent chemoradiotherapy in esophageal squamous cell carcinoma
《World Journal of Clinical Oncology》2025年第3期30-39,共10页Zhuo-Jun Wei Lin Wang Rui-Qi Wang Yu Wang Huan Chen Hong-Lian Ma Yu-Jin Xu 
Supported by Natural Science Foundation of Zhejiang Province,China,No.LGF21H160005;Zhejiang Medical and Health Science and Technology Project,China,No.2024KY049.
BACKGROUND Esophageal squamous cell carcinoma(ESCC)is a common malignancy in China,often diagnosed at an advanced stage,with poor prognosis.Standard treatments such as definitive chemoradiotherapy offer limited surviv...
关键词:Esophageal squamous cell carcinoma RADIOTHERAPY Immune checkpoint inhibitors CHEMOTHERAPY Patient safety Treatment outcome 
Multiple sclerosis is at a checkpoint: advancing the program
《Neural Regeneration Research》2025年第3期811-812,共2页Brandon C.Smith Jessica L.Williams 
Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(CNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b...
关键词:Hauser SCLEROSIS DAMAGE 
Immune checkpoint inhibitor therapy as a neoadjuvant treatment for muscle-invasive bladder carcinoma:A narrative review
《Current Urology》2025年第1期39-42,共4页Sentai Ding Chenrui Wu Jishuang Cao Jiaju Lyu 
supported by Shandong Provincial Natural Science Foundation(ZR2023LZL005);Jinan Science and Technology Development Foundation.
Immunotherapy has become a standard treatment for patients with advanced urothelial carcinoma,and neoadjuvant immunotherapy is currently being extensively explored.This reviewhighlights the initial findings and key cl...
关键词:Muscle-invasive bladder cancer Immune checkpoint inhibitor Tislelizumab Neoadjuvant immunotherapy 
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