ULCERATIVE

作品数：349被引量：1915H指数：22
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Regulatory effects of the p38 mitogen-activated protein kinase-myosin light chain kinase pathway on the intestinal epithelial mechanical barrier and the mechanism of modified Pulsatilla decoction(加味白头翁汤)in the treatment of ulcerative colitis
《Journal of Traditional Chinese Medicine》2024年第5期885-895,共11页WU Tingting YANG Xin ZHU Huiping GUO Jinwei ZHU Hui ZHANG Peipei WANG Meng LIANG Guoqiang SUN Hongwen 
Natural Science Foundation of Jiangsu Province-funded Project:Regulation of Intestinal Epithelial Tight Junction Proteins Through the p38 Mitogen-activated Protein Kinase-Myosin Light Chain kinase Signaling Pathway in Ulcerative Colitis Treatment by Modified Pulsatilla Decoction(No.BK20201179);Jiangsu Health Commission-funded Project:Study on the Prevention of Postoperative Recurrence in Patients with Colorectal Adenoma and High Triglyceride based on the Theory of“Treating the Disease Before It Gets Worse”by Modified Jisheng Wumei Pill(BJ23039);Suzhou Health Commission-funded Project:Study on the Technical Application of Xu Jingfan's“Eliminating Stasis and Protecting Membrane”Method to Regulate Recombinant NLR Family,Pyrin Domain Containing Protein 3 to Repair Esophageal Mucosa in Reflux Esophagitis treatment(SS202080),Suzhou Health Commission-funded Project:(SKY2022015),and Suzhou Health Commission-funded Project:Clinical Diagnostic and Therapeutic Techniques for Reflux Esophagitis Treatment with Graded Step-down Therapy by Combining Traditional Chinese and Western medicine(LCZX201817)。
OBJECTIVE:To investigate the mechanism of the protective effect of modified Pulsatilla decoction(加味白头翁汤,MPD)on the mechanical barrier of the ulcerative colitis(UC)intestinal epithelium in vitro and in vivo.METHO...
关键词：COLITIS ULCERATIVE mitogen-activated protein kinase 14 myosin-light-chain kinase modified pulsatilla decoction intestinal epithelial mechanical barrier experimental verification 
Investigation of the active ingredients and mechanism of Shuangling extract in dextran sulfate sodium salt induced ulcerative colitis mice based on network pharmacology and experimental verification
《Journal of Traditional Chinese Medicine》2024年第3期478-488,共11页CHU Mengzhen WANG Yu LIN Zhijian Lyu Jintao ZHANG Xiaomeng ZHANG Bing 
the Innovation Team and Talents Support Program of National Administration of Traditional Chinese Medicine:Construction and Practice of Pharmacovigilance Theory System in Line with the Characteristics of Traditional Chinese Medicine (No. ZYYCXTD-C-202005-11);the National Leading Talents Support Plan of Traditional Chinese Medicine 'Qihuang Scholar' Plan:Chinese Medicine Inheritance and Innovation "One Hundred Million" Talent Project (Qihuang Project) Qihuang Scholars (No. 1040063320004)。
OBJECTIVE: To explore the pharmacodynamic effects and potential mechanisms of Shuangling extract against ulcerative colitis(UC). METHODS: The bioinformatics method was used to predict the active ingredients and action...
关键词：COLITIS ULCERATIVE pharmacodynamic study network pharmacology molecular docking simulation Shuangling extract 
Qingchang suppositry(清肠栓)induced remission in patients with mild-to-moderate ulcerative proctitis:a multicenter,prospective,randomized,parallel-controlled clinical trial被引量：5
《Journal of Traditional Chinese Medicine》2024年第1期156-162,共7页DAI Xiaoling ZHANG Anming LIN Hui SHI Bei REN Yi WEN Hongzhu FEI Xiaoyan LIN Jiang 
Shanghai Municipal Administration of Traditional Chinese Medicine:Leadship Training Program of Inheritance and Innovation Team of Shanghai School of Traditional Chinese Medicine(No.2021WXGLP-007)。
OBJECTIVE:To evaluate the efficacy and safety of Qingchang suppository(清肠栓,QCS),a preparation of Chinese herbal medicine,in the induction of remission in patients with mild-to-moderate ulcerative proctitis(UP).METH...
关键词：ulcerative proctitis salicylazosulfapyridine suppository Qingchang suppositry randomized controlled trial 
Aeromonas veronii isolated from climbing perch(Anabas testudineus)suffering from epizootic ulcerative syndrome(EUS)
《Aquaculture and Fisheries》2023年第3期288-295,共8页Rakib Ehsan Ashikur Rahman Sulav Indra Paul Md.Ali Arman Ador Md.Shameul Haque Tasmina Akter Md.Mahbubur Rahman 
Motile Aeromonads are responsible for various diseases in fishes that cause significant economic losses in aquaculture.Aeromonas spp.are also frequently isolated from fish suffering from Epizootic Ulcerative Syndrome(...
关键词：Aeromonas veronii Anabas testudineus Epizootic ulcerative SYNDROME ANTIBIOGRAM Medicinal plant extracts 
Efficacy of Qifu Lizhong enema prescription(芪附理中灌肠方)on intestinal mucosal tight junction function modulation of ulcerative colitis rat model被引量：3
《Journal of Traditional Chinese Medicine》2023年第2期303-311,共9页CHENG Jing Lü Shangbin ZHANG Yi HU Shuangyuan WEI Pengfei ZHOU Wenhua SHI Junfeng 
Supported by National Natural Science Foundation of China:Research on the Biological Mechanism of Nourishing Fire and Nourishing Soil Building Muscle Regeneration in Repairing Intestinal Mucosal Barrier Damage in UC Based on MLCK/Rho/PKC-Crosstalk(No.81973821)。
OBJECTIVE:To investigate the efficacy and mechanism of Qifu Lizhong enema prescription(芪附理中灌肠方,QFLZ)on intervening ulcerative colitis(UC)rat model with TCM spleen and kidney Yang insufficiency syndrome METHODS:...
关键词：COLITIS ULCERATIVE CLAUDIN-1 claudin-2 zonula occludens-1 protein ACTINS Qifulizhong enema prescription 
Efficacy of active ingredients in Qingdai(Indigo Naturalis)on ulcerative colitis:a network pharmacology-based evaluation被引量：1
《Journal of Traditional Chinese Medicine》2023年第1期124-133,共10页LI Yue WEN Shuting ZHAO Runyuan FAN Dongmei ZHAO Dike LIU Fengbin MI Hong 
Supported by Natural Science Foundation of Guangdong Province:Mechanism of Chang-An Decotion in Neuropeptide Spexin related GSK-3βRegulating Intestinal Nerve Immune Network in Ulcerative Colitis(No.2018A030310614);National Natural Science Foundation of China:Mchanism of Chang-An Decotion in Intestinal Mucosal Immunity of Ulcerative Colitis on Exocrine Mediated Rab27(No.81903963);Department of Education of Guangdong Province Project:Mchanism of Chang-An decotion of Ulcerative Colitis on Exocrine Mediated GSK-3βRegulating Th17/Treg in Ulcerative Colitis(No.2017KQNCX045)。
OBJECTIVE:To elucidate the protective effect of Qingdai(Indigo Naturalis,QD)on ulcerative colitis(UC)by means of in silico and in vivo approaches.METHODS:A systems pharmacology analysis was performed to predict the ac...
关键词：Qingdai(Indigo Naturalis) colitis ulcerative glycogen synthase kinase 3 beta signaling transduction forkhead transcription factors network pharmacology 
Diagnostic dilemma in a patient with chronic non-healing ulcer on leg:A case report
《Asian Pacific Journal of Tropical Medicine》2022年第12期568-570,共3页Mendiratta Vibhu Meena Amit Singh Smita 
Rationale:Though cutaneous tuberculosis accounts for a small proportion of all tuberculosis cases,it becomes an important health issue considering its high prevalence in tropical countries.Due to its myriad clinical m...
关键词：Cutaneous tuberculosis Mantoux Ulcerative Lupus vulgaris 
Schistosoma japonicum Eggs Exerts Protective Effects in an Experimental Ulcerative Colitis Model被引量：1
《Biomedical and Environmental Sciences》2022年第11期1085-1089,共5页MA Zhen Rong SUN Xi ZHENG Wen Xiao LI Xuan Wu ZHANG Ni HUANG Ye Hong LU Bin LI Zhuo Lin NOUHOUM Di Bo YU Xin Ling ZHOU Jie CHEN Hong Zhi YANG Xue Xian WU Xiang 
supported in part by grants from National Natural Sciences Foundation of China[grant nos.82072306 and 81828004 to XW]。
Ulcerative colitis(UC)is a chronic inflammatory disease affecting the colon,with an increasing incidence worldwide.Disease pathogenesis is multifactorial and involves genetic predisposition,epithelial barrier defects,...
关键词：SCHISTOSOMA COLON ULCERATIVE 
Efficacy of Sishen Wan(四神丸) on dinitrobenzene sulfonic acid-induced ulcerative colitis and its effect on toll-like receptor 2/interleukin-1 receptor-associated kinase-4/nuclear factor-κB signal pathway被引量：8
《Journal of Traditional Chinese Medicine》2022年第4期565-575,共11页ZHANG Zhaohua LIU Rong DU Nana ZHU Xiangdong 
Supported by the National Natural Science Foundation of China:to Explore the Immune Mechanism of Treating Ulcerative Colitis by Regulating Treg/Th17 Cell Imbalance by Warming the Kidney and Invigorating the Spleen through Intestinal Flora(No.81960826)
OBJECTIVE:To investigate the therapeutic effect of Sishen Wan(四神丸,SSW)on ulcerative colitis(UC)induced by dinitrobenzene sulfonic acid and its effect on toll-like receptor 2/interleukin-1 receptor-associated kinase...
关键词：colitis ulcerative toll-like receptor 2 interleukin-1 receptor-associated kinases NF-kappa B signal transduction therapeutic uses Sishen Wan 
How has the disease course of pediatric ulcerative colitis changed throughout the biologics era?A comparison with the IBSEN study被引量：1
《World Journal of Gastroenterology》2022年第28期3666-3681,共16页Yiyoung Kwon Eun Sil Kim Yon Ho Choe Mi Jin Kim 
BACKGROUND In Korea,infliximab was approved for use in children with ulcerative colitis(UC)in October 2012.AIM To compare the clinical course of UC before and after the introduction of biological agents,and to compare...
关键词：Colitis ULCERATIVE Children INFLIXIMAB RELAPSE STEROID 
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