云南高校图书馆联盟文献共享服务平台- FMOC

FMOC: 作品数：71被引量：205H指数：9; 导出分析报告; 相关作者：甘一如王晓莺朱颐申黄鹤沈树宝更多>>; 相关机构：南京肽业生物科技有限公司南京工业大学天津大学军事医学科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金天津市自然科学基金国家高技术研究发展计划广西壮族自治区科技攻关计划更多>>

Fmoc-protected amino acids as luminescent and circularly polarized luminescence materials based on charge transfer interaction被引量：1: 《Chinese Chemical Letters》2022年第11期4918-4923,共6页Yiran Xia Aiyou Hao Pengyao Xing; supported by the Qilu Young Scholarship Funding of Shandong University;supported by the National Natural Science Foundation of China(Nos.21901145,22171165);Natural Science Foundation of Jiangsu Province(No.BK20190209);the financial support from Youth cross-scientific innovation group of Shandong University(No.2020QNQT003)。; Fluorenylmethyloxycarbonyl(Fmoc)-protected amino acids are effective building blocks in self-assembled architectures at hierarchical levels,which however show limited luminescent properties and chiroptical activities....; 关键词：Fmoc-amino acids Charge-transfer interaction Supramolecular chirality Multiple component coassembly

基于基金项目的药学创新实验设计——以“Fmoc固相合成多肽”为例被引量：1: 《嘉兴学院学报》2019年第6期136-141,共6页孙李丹黄嬛; 国家自然科学基金青年基金项目(81703346);浙江省公益技术应用研究计划项目(LGD19H070002);嘉兴市科技局项目(2017AY33074); 在基金科研成果的基础上,利用固相合成技术,设计了以9-芴甲氧羰基(Fmoc)固相多肽合成S1肽序的创新实验项目.实验采用简单易得和安全性更高的试剂,并使用高效液相色谱和质谱对合成的粗品进行纯度检测和结构确证,形成了对活性多肽合成和...; 关键词：固相合成多肽药学研究性教学

Fmoc(S)2-氨基-2-甲基戊-4-烯酸的合成路线改进被引量：1: 《当代化工》2018年第11期2285-2287,2292,共4页夏亮彭涛张首国王刚温晓雪刘曙晨王林; 国家自然科学基金,项目号:81273431,81072531,30770655,21272273和21102176; 设计合成手性非天然氨基酸。制备了五元内酯环,亲电取代后得到差相异构体。通过重结晶得到单一构型的产物,经酸水解制备得到目标产物。结果得到的非天然氨基酸经1H NMR鉴定、旋光鉴定并与标准值比对。对于已有的氨基酸合成路线进行优化...; 关键词：手性合成位阻效应新戊醛 PCC氧化一步法合成

Chemical synthesis and structural analysis of guanylate cyclase C agonist linaclotide被引量：1: 《Chinese Chemical Letters》2018年第7期1135-1138,共4页Chenchen Chen Shuai Gao Qian Qu Pengcheng Mi Anjin Tao Yi-Ming Li; supported by the National Natural Science Foundation of China (NSFC No. 21572043);the Fundamental Research Funds for the Central Universities (No. PA2017GDQT0021); Guanylate cyclase C(GC-C) is an important receptor protein expressed by intestinal epithelial cells, and its dysregulation leads to severe intestinal diseases. Linaclotide is a 14-amino acid peptide approved by the FD...; 关键词：Linaclotide Guanylyl cyclase Protein chemical synthesis Fmoc solid phase peptide synthesis Racemic crystallization

Design and Fabrication of Functional Hydrogels through Interfacial Engineering被引量：3: 《Chinese Journal of Polymer Science》2017年第10期1181-1193,共13页Lie Chen Yong-ai Yin Yu-xia Liu Ling Lin 刘明杰; financially supported by the National Natural Science Foundation of China(No.21574004);Xiamen Southern Oceanographic Center(No.14GQT61HJ31);the 111 project(No.B14009);the Fundamental Research Funds for the Central Universities;the National ‘Young Thousand Talents Program’;the Academic Excellence Foundation of BUAA for PHD Students; Hydrogels have drawn considerable attention in the past two decades due to their excellent biocompatibility and multi-stimuli responsiveness. They have a wide range of applications in the fields related to tissue engi...; 关键词：assembly bonding intermolecular aromatic stacking inherent biomedical representative Fmoc directional

Rapid and sensitive method for determining free amino acids in plant tissue by high-performance liquid chromatography with fluorescence detection被引量：1: 《Acta Geochimica》2017年第4期680-696,共17页Nengjian Zheng Huayun Xiao Zhongyi Zhang Xiaofei Gao Jingjing Zhao; financially supported by the National Key Research and Development Program of China through Grant 2016YFA0601000(H.Y.Xiao);National Natural Science Foundation of China through Grants 41425014,41273027 and 41173027(H.Y.Xiao);by the National Basic Research Program of China through Grants 2013CB956703(H.Y.Xiao); This paper describes a reliable and rapid method for the complete separation and quantitation of twenty-five amino acids typically found in plants, based on reversed phase high-performance liquid chromatography–linke...; 关键词：HPLC OPA FMOC Free amino acids PLANT PLS-DA

Synthesis and Gelation Capability of Fmoc and Boc Mono-substituted Cyclo（L-Lys-L-Lys）s: 《Chemical Research in Chinese Universities》2016年第3期484-492,共9页ZONG Qianying GENG Huimin YE Lin ZHANG Aiying SHAO Ziqiang FENG Zengguo; Supported by the National Natural Science Foundation of China（No.21174018）.; Fmoc or Boc mono-substituted cyclo（L-Lys-L-Lys）s were synthesized via the reaction of lysine cyclic dipeptide with Fmoc N-hydroxysuccinimide este（Fmoc-OSu） and di-tert-butyl dicarbonate[（Boc）20], respectively. T...; 关键词：Lysine cyclic dipeptide Low molecular weight gelator π-π Stacking NANOTUBE

Gelation capability of cysteine-modified cyclo(L-Lys-L-Lys)s dominated by Fmoc and Trt protecting groups: 《Science China Chemistry》2016年第3期293-302,共10页Huimin Geng Qianying Zong Jie You Lin Ye Aiying Zhang Ziqiang Shao Zengguo Feng; the National Natural Science Foundation of China (21174018); A series of symmetrical peptidomimetics （3-8） based on cysteine-modified cyclo（L-Lys-L-Lys）s were synthesized, and their gelation capability in organic solvents was dominated by fluorenylmethyloxycarbonyl （Fmoc）...; 关键词：ORGANOGEL cyclic dipeptide SELF-ASSEMBLY CYSTEINE β-turn

Fmoc-FF二肽分子自组装过程的分子动力学研究被引量：4: 《高等学校化学学报》2015年第11期2171-2178,共8页郭凯张恒孙继超苑世领刘成卜; 国家自然科学基金(批准号:21173128)资助~~; 采用分子动力学方法模拟研究了Fmoc-FF二肽分子在溶液中的自组装过程,探究了自组装过程中的驱动力及水桥结构对聚集体稳定性的影响.结果表明,Fmoc-FF二肽分子可以在水溶液中自组装形成结构规整的圆柱形纳米棒;根据Fmoc环间的径向分布函...; 关键词：Fmoc—FF二肽分子自组装水凝胶 Π-Π作用氢键分子动力学模拟

Recent progress of sugar amino acids: Synthetic strategies and applications as glycomimetics and peptidomimetics被引量：1: 《Chinese Chemical Letters》2015年第8期922-930,共9页Guang-Zong Tian Xiao-Li Wang Jing Hu Xue-Bin Wang Xiao-Qiang Guo Jian Yin; supported by the National Science Foundation for Young Scientists of China(No.21302068);the Natural Science Foundation of Jiangsu Province,China(No.BK20130127);Jiangsu Province‘‘Six Summit Talent’’Foundation(No.2012-SWYY-009);the Specialized Research Fund for the Doctoral Program of Higher Education(No.20120093120002);the Fundamental Research Funds for the Central Universities(Nos.JUSRP51319B,JUSRP51411B); In order to meet the increasing demands for the development of large varieties of new molecules for discovering new drugs and materials, organic chemists are developing many novel multifunctional building blocks, whic...; 关键词：structurally carboxylic oligomer blocks assembled Fmoc amide carbohydrate diverse protected

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