Toxic leukoencephalopathy is an important complication of heroin abuse and has mostly been described after inhaling heroin vapor, known as “chasing the dragon syndrome” or heroin inhalation leukoencephalopathy (HIL)...
Background: Whilst several studies have demonstrated poor cardiovascular health in opiate dependence, its role as a cardiovascular risk factor has not been considered. Methods: Pulse wave analysis was undertaken by ra...
This work was supported hy grants from Ministry of Science and Technology (G1999053907 and G1999054003), Chinces Academy of Sciences (KSCX2-2-02), the National Natural Science Foundation of China (39825110 and 30024003). and the German Max-Planck Society. We greatly thank Dr. M.-m. Poo for his critical comments on this manuscript and Drs. S.-m, Duan, B,-m, Li, and P. Xia for their technical help.
The present study was designed to determine the changes of phosphorylation of cAMP- response ele-ment binding protein (CREB) in hippocampus induced by ohmefentanyl stereoisomers (F9202 and F9204)in conditioned place p...
Many opioids-mediated responses, including the inhibition of forskolin-stimulated cyclic-AMP accumulation, the activation of an inwardly rectifying K^+ channel, and antinociception, are diminished by repeated exposure...
The multiplicity of opiate receptors has turned out to be the most attractive to workers in this field, since Martin et al. (1976) pointed out the possible existence of more than one subtypes Of opiate receptors. Rat ...