GLYCOSYLATED

作品数:37被引量:79H指数:5
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相关领域:医药卫生生物学更多>>
相关作者:黄刚良更多>>
相关机构:北京大学中国农业科学院重庆师范大学更多>>
相关期刊:《Chinese Medical Journal》《World Journal of Diabetes》《Chemical Research in Chinese Universities》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
相关基金:国家自然科学基金上海市自然科学基金高等学校学科创新引智计划中国博士后科学基金更多>>
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Syntheses and Anti-cancer Activities of Glycosylated Derivatives of Diosgenin被引量:1
《Chemical Research in Chinese Universities》2017年第1期80-86,共7页TAN Yonghua XIAO Xiao YAO Jianing HAN Fei LOU Huayong LUO Heng LIANG Guangyi BEN-DAVID Yaacov PAN Weidong 
Supported by the National Natural Science Foundation of China(Nos.81360479, 81472609) and the Project of the Science and Technology Department of Guizhou Province, China(Nos.QKHRC[2016]4037,QKHRCTD[2015]4026, QKHJZ[2014]2099).
In order to obtain better anti-cancer compounds, nine glycosylated derivatives were designed and synthe- sized using diosgenin as starting material. Their structures were confn-med by 1H NMR, 13C NMR and MS spectra. T...
关键词:DIOSGENIN GLYCOSYLATION Anti-cancer activity 
Design and Synthesis of Glycosylated Aromatic Nitrogen Mustard Derivatives被引量:5
《Chemical Research in Chinese Universities》2007年第3期300-302,共3页LIU Tie-mei WANG Shu-sheng ZHU Guang-ze LI Ming-yang ZHANG Li-ping 
Supported by the National Natural Science Foundation of China(No20030708);the Natural Science Foundation of JinlinProrince, P R China(No20050702-4)
Antibody-directed enzyme prodrug therapy(ADEPT) is a new strategy for the treatment of cancer that has arisen in recent twenty years, the main merits of which are that it can improve the selectivity of anticancer dr...
关键词:GLYCOSYLATION Nitrogen mustard derivative PRODRUG ADEPT 
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