INTERFERON-ALPHA

作品数：52被引量：295H指数：10
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相关领域：医药卫生更多>>
相关作者：陈光慧郭艳红沈冬张国华杨文艺更多>>
相关机构：北京大学同济医科大学附属协和医院中山大学上海赛伦生物技术股份有限公司更多>>
相关期刊：《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《Virologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金吉林省卫生厅科研基金国家重点基础研究发展计划广西壮族自治区自然科学基金更多>>
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Successful treatment of depressed esophageal squamous papilloma with interferon-alpha 2a:A case report
《World Journal of Clinical Cases》2025年第19期38-42,共5页Jiong Jiang Hai-Tao Shi Jie Wu Su-Mei Sha Shang-Xuan Cai Xin Liu 
Supported by Key Research&Development Program of Shaanxi Province,No.2021SF-221.
BACKGROUND Esophageal squamous papilloma(ESP)is a rare benign tumor of the esophagus,typically characterized by an exophytic and warty appearance,with a diameter of less than 5 mm.Endoscopic resection is considered th...
关键词：PAPILLOMA ESOPHAGUS Interferon-alpha 2a Human papillomavirus Case report 
C-X-C chemokine receptor type 5+CD8+T cells as immune regulators in hepatitis Be antigen-positive chronic hepatitis B under interferonalpha treatment
《World Journal of Gastroenterology》2025年第3期73-83,共11页Zhen-Yu Xu Zhong-Shang Dai Guo-Zhong Gong Min Zhang 
Supported by Changsha Science and Technology Program,No.kq2022397;Natural Science Foundation of Hunan Province(Departmental Joint Fund),No.2023JJ60440;Research Program of Health Commission of Hunan Province,No.202303088786;Clinical Medical Research Center for Viral Hepatitis of Hunan Province,No.2023SK4009;the Scientific Research Program of FuRong Laboratory,No.2023SK2108.
BACKGROUND C-X-C chemokine receptor type 5(CXCR5)^(+)CD8^(+)T cells represent a unique immune subset with dual roles,functioning as cytotoxic cells in persistent viral infections while promoting B cell responses.Despi...
关键词：C-X-C chemokine receptor type 5 Programmed death-ligand 1 INTERLEUKIN-21 Pegylated interferon-alpha Chronic hepatitis B 
Consolidation treatment needed for sustained HBsAg-negative response induced by interferon-alpha in HBeAg positive chronic hepatitis B patients被引量：13
《Virologica Sinica》2022年第3期390-397,共8页Minghui Li Fangfang Sun Xiaoyue Bi Yanjie Lin Liu Yang Yao Lu Lu Zhang Gang Wan Wei Yi Linqing Zhao Yao Xie 
funded in part by the Beijing Municipal Science and Technology Commission(No.Z151100004015122);Beijing Municipal Administration of Hospitals’Clinical Medicine Development of special funding support(No.XMLX 201706 and XMLX202127);National Science and Technology Major Project of China(2017ZX10203202-003,2017ZX10201201-001-006,and 2017ZX10201201-002-006);Beijing Science and Technology Commission(No.D161100002716002);Digestive Medical Coordinated Development Center of Beijing Municipal Administration of Hospitals(No.XXZ0302 and XXT28);Special public health project of Capital health development(2021-1G-4061 and 2022-1-2172)。
Hepatitis B surface antigen(HBsAg)clearance is considered as functional cure in patients with chronic hepatitis B(CHB).This study aimed to assess the durability of HBsAg clearance achieved by interferon-based therapie...
关键词：Chronic hepatitis B(CHB) Functional cure HBeAg positive HBsAg loss Interferon(IFN) 
Innate Immune Response in Human Kidney Transplantation: IRF3 and IRF7 Together with Interferon-Alpha Are Significantly Up-Regulated in Acute Rejection
《Open Journal of Nephrology》2021年第3期379-396,共18页Paula Xavier Dias-Pinto José Gerardo G. Oliveira 
Background: Ischemia-reperfusion injury of organ transplantation activates several mediators which may link the innate to the adaptive immune response. Down the cascade of TLRs, we selected to study t...
关键词：Kidney Transplants Aspiration Biopsies Innate Immunity IRF IFN-α 
Role of interferons in diabetic retinopathy被引量：1
《World Journal of Diabetes》2021年第7期939-953,共15页Bing-Yan Li Wei Tan Jing-Ling Zou Yan He Shigeo Yoshida Bing Jiang Ye-Di Zhou 
Supported by National Natural Science Foundation of China,No.81800855 and No.82070967;Natural Science Foundation of Hunan Province,No.2018JJ3765.
Diabetic retinopathy(DR)is one of the major causes of visual impairment and irreversible blindness in developed regions.Aside from abnormal angiogenesis,inflammation is the most specific and might be the initiating fa...
关键词：INTERFERONS CYTOKINES Diabetic retinopathy INTERFERON-ALPHA Interferongamma INFLAMMATION 
Comparative effectiveness and safety of ribavirin plus interferon-alpha,lopinavir/ritonavir plus interferon-alpha,and ribavirin plus lopinavir/ritonavir plus interferon-alpha in patients with mild to moderate novel coronavirus disease 2019:study protocol被引量：2
《Chinese Medical Journal》2020年第9期1132-1134,共3页Yan-Ming Zeng Xiao-Lei Xu Xiao-Qing He Sheng-Quan Tang Yao Li Yin-Qiu Huang Vijay Harypursat Yao-Kai Chen 
This work was supported by the Chongqing Special Research Project for Prevention and Control of Novel Coronavirus Pneumonia(No.cstc2020jscx-fyzx0074)。
To the Editor:At the end of 2019,an outbreak of novel coronavirus disease 2019(COVID-19),caused by 2019-nCov,causing widespread novel coronavirus disease.This outbreak of COVID-19 occurred during the period of the 202...
关键词：PATIENTS RIBAVIRIN INTERFERON 
Effects of hepatitis E virus infection on interferon production via ISG15被引量：2
《World Journal of Gastroenterology》2018年第20期2173-2180,共8页Min Wang Ying Huang Man He Wen-Ju Peng De-Ying Tian 
Supported by the National Natural Science Foundation of China,No.81570540
AIM To assess the effects of hepatitis E virus(HEV) on the production of type Ⅰ interferons(IFNs) and determine the underlying mechanisms.METHODS We measured the production of interferon(IFN)-alpha and-beta(-α/β) i...
关键词：open reading frame 3 interferon-stimulated gene 15 INTERFERON-ALPHA HEPATITIS E virus interferonbeta 
Clinical correlations between chronic hepatitis C infection and decreasing bone mass density after treatment with interferon-alpha被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2017年第2期161-165,共5页Vahid Babaei Masoud Ghorbani Nastaran Mohseni Hojjat Afraid Yassaman Saghaei Shahram Teimourian 
Supported by Iran National Science Foundation(Grant No.91002993)
Objective: To compare the bone mass density in chronic hepatitis patients before and after interferon-a treatment.Methods: A total of 70 patients with chronic hepatitis C were treated with interferon-a and were evalua...
关键词：Hepatitis C Interferon alpha Bone mass density Liver fibrosis Bone mass loss 
Psychosocial assessment and monitoring in the new era of non-interferon-alpha hepatitis C virus treatments被引量：1
《World Journal of Hepatology》2015年第19期2209-2213,共5页Paul J Rowan Nizar Bhulani 
Chronic hepatitis C virus(HCV) is a global concern. With the 2014 Food and Drug Administration approvals of two direct-acting antiviral(DAA) regimens, ledipasvir/sofosbuvir regimen and the ombitasvir/paritaprevir/rito...
关键词：DEPRESSION Therapy PSYCHIATRY Clinical Direct-acti 
A Follow-up Study for Chinese Chronic Hepatitis C Patients Treated with the Combination of PEG-IFNα-2a(PEGASYS) and Ribavirin
《国际感染病学（电子版）》2014年第3期103-107,共5页Zhu Chen Yi-lan Zeng Li Wang Rong Hu Yan Wang Yu-zhen Tang Li Zhu Bei Wu 
Objective To compare the efficacy of peginterferon alfa-2a(PEGASYS) plus ribavirin(RBV) with interferon alfa-2a plus RBV, and evaluate the safety. Methods Total of 117 patients with chronic hepatitis C were enrolled t...
关键词：Chronic hepatitis C Interferon-alpha Ribavirin Treatment outcome 
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